作者：Tomar, A.; Gomez-Velazquez, M.; Gerlini, R.; Comas-Armangue, G.; Makharadze, L.; Kolbe, T.; Boersma, A.; Dahlhoff, M.; Burgstaller, J. P.; Lassi, M.; Darr, J.; Toppari, J.; Virtanen, H.; Kuehnapfel, A.; Scholz, M.; Landgraf, K.; Kiess, W.; Vogel, M.; Gailus-Durner, V.; Fuchs, H.; Marschall, S.; Hrabe de Angelis, M.; Kotaja, N.; Koerner, A.; Teperino, R.
作者单位：Helmholtz Association; Helmholtz-Center Munich - German Research Center for Environmental Health; German Center for Diabetes Research (DZD); University of Veterinary Medicine Vienna; BOKU University; University of Veterinary Medicine Vienna; BOKU University; University of Turku; University of Turku; University of Turku; Leipzig University; Leipzig University; Leipzig University; Helmholtz Association; Helmholtz-Center Munich - German Research Center for Environmental Health; Technical University of Munich; Helmholtz Association; Helmholtz-Center Munich - German Research Center for Environmental Health; Leipzig University; Leipzig University
摘要：Spermatozoa harbour a complex and environment-sensitive pool of small non-coding RNAs (sncRNAs)(1), which influences offspring development and adult phenotypes(1-7). Whether spermatozoa in the epididymis are directly susceptible to environmental cues is not fully understood(8). Here we used two distinct paradigms of preconception acute high-fat diet to dissect epididymal versus testicular contributions to the sperm sncRNA pool and offspring health. We show that epididymal spermatozoa, but not ...
作者：Eisenstein, Michael
摘要：A steadily growing toolbox is giving researchers the ability to monitor and measure the physical forces that shape embryonic development.
作者：Lewis, Dyani; Abbott, Alison
