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作者：Conroy, Gemma
摘要：The US$5 billion facility would be cheaper, bigger and faster to build than a similar one proposed by European scientists.
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作者：Holmes, K. John
作者单位：National Academies of Sciences, Engineering & Medicine
摘要：Science and reason underpinned early surveys, but sociopolitical ideals left their mark on the nation too, a historical account concludes.
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作者：Jaffe, Yitzchak; Caramanica, Ari; Price, Max
作者单位：University of Haifa; Vanderbilt University; Durham University
摘要：Letter to the Editor
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作者：Tschitschko, Bernhard; Esti, Mertcan; Philippi, Miriam; Kidane, Abiel T.; Littmann, Sten; Kitzinger, Katharina; Speth, Daan R.; Li, Shengjie; Kraberg, Alexandra; Tienken, Daniela; Marchant, Hannah K.; Kartal, Boran; Milucka, Jana; Mohr, Wiebke; Kuypers, Marcel M. M.
作者单位：Max Planck Society; University of Vienna; Helmholtz Association; Alfred Wegener Institute, Helmholtz Centre for Polar & Marine Research; University of Bremen; Constructor University; University of Innsbruck
摘要：Nitrogen (N2) fixation in oligotrophic surface waters is the main source of new nitrogen to the ocean 1 and has a key role in fuelling the biological carbon pump 2 . Oceanic N2 fixation has been attributed almost exclusively to cyanobacteria, even though genes encoding nitrogenase, the enzyme that fixes N2 into ammonia, are widespread among marine bacteria and archaea 3-5 . Little is known about these non-cyanobacterial N2 fixers, and direct proof that they can fix nitrogen in the ocean has so...
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作者：Yang, Yonghang; Liang, Baokun; Kreie, Jakob; Hambsch, Mike; Liang, Zihao; Wang, Cheng; Huang, Senhe; Dong, Xin; Gong, Li; Liang, Chaolun; Lou, Dongyang; Zhou, Zhipeng; Lu, Jiaxing; Yang, Yang; Zhuang, Xiaodong; Qi, Haoyuan; Kaiser, Ute; Mannsfeld, Stefan C. B.; Liu, Wei; Goelzhaeuser, Armin; Zheng, Zhikun
作者单位：Sun Yat Sen University; Sun Yat Sen University; Guangdong University of Technology; Ulm University; University of Bielefeld; Technische Universitat Dresden; Technische Universitat Dresden; Shanghai Jiao Tong University; Sun Yat Sen University; Southern Marine Science & Engineering Guangdong Laboratory; Southern Marine Science & Engineering Guangdong Laboratory (Guangzhou)
摘要：The properties of polycrystalline materials are often dominated by defects; two-dimensional (2D) crystals can even be divided and disrupted by a line defect1-3. However, 2D crystals are often required to be processed into films, which are inevitably polycrystalline and contain numerous grain boundaries, and therefore are brittle and fragile, hindering application in flexible electronics, optoelectronics and separation1-4. Moreover, similar to glass, wood and plastics, they suffer from trade-of...
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作者：Tou, Connor J.; Kleinstiver, Benjamin P.
作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Massachusetts Institute of Technology (MIT); Harvard University; Harvard Medical School
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作者：de la Gandara, Alvaro; Spinola-Amilibia, Mercedes; Araujo-Bazan, Lidia; Nunez-Ramirez, Rafael; Berger, James M.; Arias-Palomo, Ernesto
作者单位：Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro de Investigaciones Biologicas (CIB); Johns Hopkins University
摘要：Transposases drive chromosomal rearrangements and the dissemination of drug-resistance genes and toxins1-3. Although some transposases act alone, many rely on dedicated AAA+ ATPase subunits that regulate site selectivity and catalytic function through poorly understood mechanisms. Using IS21 as a model transposase system, we show how an ATPase regulator uses nucleotide-controlled assembly and DNA deformation to enable structure-based site selectivity, transposase recruitment, and activation an...
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作者：Gebel, Luka; Velu, Chander; Vidal-Puig, Antonio
作者单位：University of London; King's College London; University of London; University College London; University of Cambridge; University of Cambridge
摘要：One UK institute has produced a dozen Nobel laureates and biomedical breakthroughs across the board. How does Cambridge's Laboratory of Molecular Biology do it? Our study found out.
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作者：Yang, Joshua; Van Gasse, Kasper; Lukin, Daniil M.; Guidry, Melissa A.; Ahn, Geun Ho; White, Alexander D.; Vuckovic, Jelena
作者单位：Stanford University; Interuniversity Microelectronics Centre; Ghent University
摘要：Titanium:sapphire (Ti:sapphire) lasers have been essential for advancing fundamental research and technological applications, including the development of the optical frequency comb1, two-photon microscopy2 and experimental quantum optics3,4. Ti:sapphire lasers are unmatched in bandwidth and tuning range, yet their use is restricted because of their large size, cost and need for high optical pump powers5. Here we demonstrate a monocrystalline titanium:sapphire-on-insulator (Ti:SaOI) photonics ...
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作者：Durrant, Matthew G.; Perry, Nicholas T.; Pai, James J.; Jangid, Aditya R.; Athukoralage, Januka S.; Hiraizumi, Masahiro; McSpedon, John P.; Pawluk, April; Nishimasu, Hiroshi; Konermann, Silvana; Hsu, Patrick D.
作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of California San Francisco; University of Tokyo; University of Tokyo; University of Tokyo; Japan Science & Technology Agency (JST); Stanford University; University of California System; University of California Berkeley
摘要：Genomic rearrangements, encompassing mutational changes in the genome such as insertions, deletions or inversions, are essential for genetic diversity. These rearrangements are typically orchestrated by enzymes that are involved in fundamental DNA repair processes, such as homologous recombination, or in the transposition of foreign genetic material by viruses and mobile genetic elements1,2. Here we report that IS110 insertion sequences, a family of minimal and autonomous mobile genetic elemen...
