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作者：Xia, Huan; Zhang, Dongju; Wang, Jian; Fagernaes, Zandra; Li, Ting; Li, Yuanxin; Yao, Juanting; Lin, Dongpeng; Troche, Gaudry; Smith, Geoff M.; Chen, Xiaoshan; Cheng, Ting; Shen, Xuke; Han, Yuanyuan; Olsen, Jesper V.; Shen, Zhongwei; Pei, Zhiqi; Hublin, Jean-Jacques; Chen, Fahu; Welker, Frido
作者单位：Lanzhou University; Chinese Academy of Sciences; Lanzhou University; Lanzhou University; University of Copenhagen; University of Kent; University of Reading; University of Copenhagen; Universite PSL; College de France; Institut National de la Sante et de la Recherche Medicale (Inserm); Max Planck Society; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
摘要：Genetic and fragmented palaeoanthropological data suggest that Denisovans were once widely distributed across eastern Eurasia1-3. Despite limited archaeological evidence, this indicates that Denisovans were capable of adapting to a highly diverse range of environments. Here we integrate zooarchaeological and proteomic analyses of the late Middle to Late Pleistocene faunal assemblage from Baishiya Karst Cave on the Tibetan Plateau, where a Denisovan mandible and Denisovan sedimentary mitochondr...
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作者：Dong, Bowei; Brueckerhoff-Plueckelmann, Frank; Meyer, Lennart; Dijkstra, Jelle; Bente, Ivonne; Wendland, Daniel; Varri, Akhil; Aggarwal, Samarth; Farmakidis, Nikolaos; Wang, Mengyun; Yang, Guoce; Lee, June Sang; He, Yuhan; Gooskens, Emmanuel; Kwong, Dim-Lee; Bienstman, Peter; Pernice, Wolfram H. P.; Bhaskaran, Harish
作者单位：University of Oxford; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Microelectronics (IME); Ruprecht Karls University Heidelberg; University of Munster; Ghent University; Interuniversity Microelectronics Centre
摘要：Advancements in optical coherence control1-5 have unlocked many cutting-edge applications, including long-haul communication, light detection and ranging (LiDAR) and optical coherence tomography6-8. Prevailing wisdom suggests that using more coherent light sources leads to enhanced system performance and device functionalities9-11. Our study introduces a photonic convolutional processing system that takes advantage of partially coherent light to boost computing parallelism without substantiall...
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作者：Gibney, Elizabeth
摘要：Researchers gave successive versions of a large language model information produced by previous generations of the AI - and observed rapid collapse.
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作者：[Anonymous]
摘要：Early-career researchers are being targeted by organizers of exploitative meetings. There needs to be more awareness and perhaps legal redress over this dangerous development.
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作者：Aidukas, Tomas; Phillips, Nicholas W.; Diaz, Ana; Poghosyan, Emiliya; Mueller, Elisabeth; Levi, A. F. J.; Aeppli, Gabriel; Guizar-Sicairos, Manuel; Holler, Mirko
作者单位：Swiss Federal Institutes of Technology Domain; Paul Scherrer Institute; University of Southern California; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Federal Institutes of Technology Domain; ETH Zurich; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Mineral Resources
摘要：Advances in science, medicine and engineering rely on breakthroughs in imaging, particularly for obtaining multiscale, three-dimensional information from functional systems such as integrated circuits or mammalian brains. Achieving this goal often requires combining electron- and photon-based approaches. Whereas electron microscopy provides nanometre resolution through serial, destructive imaging of surface layers1, ptychographic X-ray computed tomography2 offers non-destructive imaging and ha...
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作者：Fava, S.; De Vecchi, G.; Jotzu, G.; Buzzi, M.; Gebert, T.; Liu, Y.; Keimer, B.; Cavalleri, A.
作者单位：Max Planck Society; Max Planck Society; University of Oxford
摘要：Coherent optical driving in quantum solids is emerging as a research frontier, with many reports of interesting non-equilibrium quantum phases(1-4) and transient photo-induced functional phenomena such as ferroelectricity(5,6), magnetism(7-10) and superconductivity(11-14). In high-temperature cuprate superconductors, coherent driving of certain phonon modes has resulted in a transient state with superconducting-like optical properties, observed far above their transition temperature T-c and th...
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作者：Miller, Richard A.
作者单位：University of Michigan System; University of Michigan; University of Michigan System; University of Michigan
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作者：Morffy, Nicholas; Van den Broeck, Lisa; Miller, Caelan; Emenecker, Ryan J.; Bryant, John A., Jr.; Lee, Tyler M.; Sageman-Furnas, Katelyn; Wilkinson, Edward G.; Pathak, Sunita; Kotha, Sanjana R.; Lam, Angelica; Mahatma, Saloni; Pande, Vikram; Waoo, Aman; Wright, R. Clay; Holehouse, Alex S.; Staller, Max V.; Sozzani, Rosangela; Strader, Lucia C.
作者单位：Duke University; North Carolina State University; Washington University (WUSTL); Washington University (WUSTL); Virginia Polytechnic Institute & State University; University of California System; University of California Berkeley
摘要：Gene expression in Arabidopsis is regulated by more than 1,900 transcription factors (TFs), which have been identified genome-wide by the presence of well-conserved DNA-binding domains. Activator TFs contain activation domains (ADs) that recruit coactivator complexes; however, for nearly all Arabidopsis TFs, we lack knowledge about the presence, location and transcriptional strength of their ADs(1). To address this gap, here we use a yeast library approach to experimentally identify Arabidopsi...
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作者：Ro, Christine
摘要：Researchers who have fallen prey to predatory conferences share the tell-tale signs of a dud event.
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作者：Widjaja, Anissa A.; Lim, Wei-Wen; Viswanathan, Sivakumar; Chothani, Sonia; Ben Corden; Dasan, Cibi Mary; Goh, Joyce Wei Ting; Lim, Radiance; Singh, Brijesh K.; Tan, Jessie; Pua, Chee Jian; Lim, Sze Yun; Adami, Eleonora; Schafer, Sebastian; George, Benjamin L.; Sweeney, Mark; Xie, Chen; Tripathi, Madhulika; Sims, Natalie A.; Huebner, Norbert; Petretto, Enrico; Withers, Dominic J.; Ho, Lena; Gil, Jesus; Carling, David; Cook, Stuart A.
作者单位：National University of Singapore; National Heart Centre Singapore; Barts Health NHS Trust; Helmholtz Association; Max Delbruck Center for Molecular Medicine; St. Vincent's Institute of Medical Research; St Vincent's Health; St Vincent's Hospital Melbourne; NSW Health; St Vincents Hospital Sydney; University of Melbourne; German Centre for Cardiovascular Research; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; China Pharmaceutical University; Imperial College London
摘要：For healthspan and lifespan, ERK, AMPK and mTORC1 represent critical pathways and inflammation is a centrally important hallmark(1-7). Here we examined whether IL-11, a pro-inflammatory cytokine of the IL-6 family, has a negative effect on age-associated disease and lifespan. As mice age, IL-11 is upregulated across cell types and tissues to regulate an ERK-AMPK-mTORC1 axis to modulate cellular, tissue- and organismal-level ageing pathologies. Deletion of Il11 or Il11ra1 protects against metab...
