作者：Gao, Wenqing; Kim, Min Woo; Dykstra, Taitea; Du, Siling; Boskovic, Pavle; Lichti, Cheryl F.; Ruiz-Cardozo, Miguel A.; Gu, Xingxing; Weizman Shapira, Tal; Rustenhoven, Justin; Molina, Camilo; Smirnov, Igor; Merbl, Yifat; Ray, Wilson Z.; Kipnis, Jonathan
作者单位：Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Saint Louis University; Washington University (WUSTL); Weizmann Institute of Science
摘要：Traumatic injuries to the central nervous system (CNS) afflict millions of individuals worldwide1, yet an effective treatment remains elusive. Following such injuries, the site is populated by a multitude of peripheral immune cells, including T cells, but a comprehensive understanding of the roles and antigen specificity of these endogenous T cells at the injury site has been lacking. This gap has impeded the development of immune-mediated cellular therapies for CNS injuries. Here, using singl...
