作者:de Leaniz, Carlos Garcia; Mouchlianitis, Foivos A.
作者单位:Universidade de Vigo
作者:Rodrigues, Meghie
摘要:Four Latin American researchers reflect on their experiences bridging the gap between science and policy in the region.
作者:Comfort, Nathaniel
作者单位:University of California System; University of California Berkeley; Johns Hopkins University
作者:Yang, Ran; Hunker, Olivia; Wise, Marleigh; Bleichert, Franziska
作者单位:Yale University
摘要:Loading of replicative helicases is obligatory for the assembly of DNA replication machineries. The eukaryotic MCM2-7 replicative helicase motor is deposited onto DNA by the origin recognition complex (ORC) and co-loader proteins as a head-to-head double hexamer to license replication origins. Although extensively studied in budding yeast(1-4), the mechanisms of origin licensing in multicellular eukaryotes remain poorly defined. Here we use biochemical reconstitution and electron microscopy to...
作者:Baker, Simon
摘要:Many of the solutions to global challenges are coming from this expanding field.
作者:Crow, James Mitchell
摘要:Finding answers to climate problems - and the financial benefits this might bring - is driving advances.
作者:Sundaram, Subramanian; Lee, Joshua H.; Bjorge, Isabel M.; Michas, Christos; Kim, Sudong; Lammers, Alex; Mano, Joao F.; Eyckmans, Jeroen; White, Alice E.; Chen, Christopher S.
作者单位:Boston University; Boston University; Harvard University; Universidade de Aveiro; Boston University; Boston University; Boston University
摘要:Natural tissues are composed of diverse cells and extracellular materials whose arrangements across several length scales-from subcellular lengths(1) (micrometre) to the organ scale(2) (centimetre)-regulate biological functions. Tissue-fabrication methods have progressed to large constructs, for example, through stereolithography(3) and nozzle-based bioprinting(4,5), and subcellular resolution through subtractive photoablation(6-8). However, additive bioprinting struggles with sub-nozzle/voxel...
作者:Heidt, Amanda
摘要:How scientific 'shorthand' could be introducing data distortions into published papers