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作者：Arrick, G.; Sticker, D.; Ghazal, A.; Lu, Y.; Duncombe, T.; Gwynne, D.; Mouridsen, B.; Wainer, J.; Jepsen, J. P. H.; Last, T. S.; Schultz, D.; Hess, K.; Medina De Alba, E.; Min, S.; Poulsen, M.; Anker, C.; Karandikar, P.; Pedersen, H. D.; Collins, J.; Egecioglu, N. E.; Tamang, S.; Cleveland, C.; Ishida, K.; Uhrenfeldt, A. H.; Kuosmanen, J.; Pereverzina, M.; Hayward, A.; Kirk, R. K.; You, S.; Dalsgaard, C. M.; Gunnarsson, S. B.; Patsi, I.; Bohr, A.; Azzarello, A.; Frederiksen, M. R.; Herskind, P.; Li, J.; Roxhed, N.; Rahbek, U. L.; Water, J. J.; Buckley, S. T.; Traverso, G.
作者单位：Massachusetts Institute of Technology (MIT); Novo Nordisk; Massachusetts Institute of Technology (MIT); Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard Medical School; Royal Institute of Technology; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
摘要：Needle-based injections currently enable the administration of a wide range of biomacromolecule therapies across the body, including the gastrointestinal tract(1-3), through recent developments in ingestible robotic devices(4-7). However, needles generally require training, sharps management and disposal, and pose challenges for autonomous ingestible systems. Here, inspired by the jetting systems of cephalopods, we have developed and evaluated microjet delivery systems that can deliver jets in...
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作者：Castelvecchi, Davide
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作者：Chen, Cheng; Nuckolls, Kevin P.; Ding, Shuhan; Miao, Wangqian; Wong, Dillon; Oh, Myungchul; Lee, Ryan L.; He, Shanmei; Peng, Cheng; Pei, Ding; Li, Yiwei; Hao, Chenyue; Yan, Haoran; Xiao, Hanbo; Gao, Han; Li, Qiao; Zhang, Shihao; Liu, Jianpeng; He, Lin; Watanabe, Kenji; Taniguchi, Takashi; Jozwiak, Chris; Bostwick, Aaron; Rotenberg, Eli; Li, Chu; Han, Xu; Pan, Ding; Liu, Zhongkai; Dai, Xi; Liu, Chaoxing; Bernevig, B. Andrei; Wang, Yao; Yazdani, Ali; Chen, Yulin
作者单位：ShanghaiTech University; ShanghaiTech University; University of Oxford; Princeton University; Princeton University; Emory University; University of California System; University of California Santa Barbara; Wuhan University; Beijing Normal University; National Institute for Materials Science; National Institute for Materials Science; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Hong Kong University of Science & Technology; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Basque Foundation for Science; Clemson University; Massachusetts Institute of Technology (MIT); Pohang University of Science & Technology (POSTECH)
摘要：The unusual properties of superconductivity in magic-angle twisted bilayer graphene (MATBG) have sparked considerable research interest(1-13). However, despite the dedication of intensive experimental efforts and the proposal of several possible pairing mechanisms(14-24), the origin of its superconductivity remains elusive. Here, by utilizing angle-resolved photoemission spectroscopy with micrometre spatial resolution, we reveal flat-band replicas in superconducting MATBG, where MATBG is unali...
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作者：Lu, Peng; Xu, Jiaoyan; Sun, Yiqing; Guillet-Nicolas, Remy; Willhammar, Tom; Fahda, Mohammad; Dib, Eddy; Wang, Bo; Qin, Zhengxing; Xu, Hongyi; Cho, Jung; Liu, Zhaopeng; Yu, Haijun; Yang, Xiaobo; Lang, Qiaolin; Mintova, Svetlana; Zou, Xiaodong; Valtchev, Valentin
作者单位：Chinese Academy of Sciences; Qingdao Institute of Bioenergy & Bioprocess Technology, CAS; Stockholm University; Universite de Caen Normandie; Centre National de la Recherche Scientifique (CNRS); China University of Petroleum
摘要：Zeolites are crystalline microporous materials constructed by corner-sharing tetrahedra (SiO4 and AlO4), with many industrial applications as ion exchangers, adsorbents and heterogeneous catalysts(1-4). However, the presence of micropores impedes the use of zeolites in areas dealing with bulky substrates. Introducing extrinsic mesopores, that is, intercrystal/intracrystal mesopores, in zeolites is a solution to overcome the diffusion barrier(5-8). Still, those extrinsic mesopores are generally...
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作者：[Anonymous]
摘要：AI companies want to give machines human-level intelligence. The safest and best results will come when academic and industry scientists oversee it together.
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作者：[Anonymous]
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作者：[Anonymous]
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作者：Jones, Nicola
摘要：AI developers are rapidly picking the Internet clean to train large language models such as those behind ChatGPT. Here's how they are trying to get around the problem.
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作者：Qvarnstrom, Martin; Wernstrom, Joel Vikberg; Wawrzyniak, Zuzanna; Barbacka, Maria; Pacyna, Grzegorz; Gorecki, Artur; Ziaja, Jadwiga; Jarzynka, Agata; Owocki, Krzysztof; Sulej, Tomasz; Marynowski, Leszek; Pienkowski, Grzegorz; Ahlberg, Per E.; Niedzwiedzki, Grzegorz
作者单位：Uppsala University; UiT The Arctic University of Tromso; University of Silesia in Katowice; Polish Academy of Sciences; W. Szafer Institute of Botany of the Polish Academy of Sciences; Jagiellonian University; Polish Academy of Sciences; Institute of Geological Sciences of the Polish Academy of Sciences; Polish Academy of Sciences; Institute of Paleobiology of the Polish Academy of Sciences; Polish Geological Institute - National Research Institute
摘要：The early radiation of dinosaurs remains a complex and poorly understood evolutionary event(1-4). Here we use hundreds of fossils with direct evidence of feeding to compare trophic dynamics across five vertebrate assemblages that record this event in the Triassic-Jurassic succession of the Polish Basin (central Europe). Bromalites, fossil digestive products, increase in size and diversity across the interval, indicating the emergence of larger dinosaur faunas with new feeding patterns. Well-pr...
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作者：Sonke, Gabe S.; van Ommen-Nijhof, Annemiek; Wortelboer, Noor; van der Noort, Vincent; Swinkels, Astrid C. P.; Blommestein, Hedwig M.; Paez, Cristina Guerrero; Mol, Linda; Beeker, Aart; Beelen, Karin; Hamming, Lisanne C.; Heijns, Joan B.; Honkoop, Aafke H.; de Jong, Paul C.; van Rossum-Schornagel, Quirine C.; van Schaik-van de Mheen, Christa; Tol, Jolien; Tromp-van Driel, Cathrien S.; Vrijaldenhoven, Suzan; van Leeuwen-Stok, A. Elise; Konings, Inge R.; Jager, Agnes; de Jong, Paul C.
作者单位：Netherlands Cancer Institute; Erasmus University Rotterdam; Erasmus MC; Erasmus MC Cancer Institute; Netherlands Cancer Institute; Erasmus University Rotterdam - Excl Erasmus MC; Erasmus University Rotterdam; Spaarne Hospital; Rijnstate Hospital; Medical Center Leeuwarden; Amphia Hospital; Isala Clinics; St. Antonius Hospital Utrecht; Franciscus Gasthuis; Meander Medisch Centrum; Jeroen Bosch Ziekenhuis; Gelre Hospitals; Medical Center Of Alkmaar; Vrije Universiteit Amsterdam; University of Amsterdam
摘要：Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) in combination with endocrine therapy improve the outcomes of patients with hormone-receptor (HR)-positive, HER2-negative advanced breast cancer and can be used early as first-line treatment or deferred to second-line treatment(1-7). Randomized data comparing the use of CDK4/6i in the first- and second-line setting are lacking. The phase 3 SONIA trial (NCT03425838) randomized 1,050 patients who had not received previous therapy for advanced ...
