2024

最新文章

• Country-specific net-zero strategies of the pulp and paper industry AI翻译
  作者：Dai, Min; Sun, Mingxing; Chen, Bin; Shi, Lei; Jin, Mingzhou; Man, Yi; Liang, Ziyang; de Almeida, Cecilia Maria Villas Boas; Li, Jiashuo; Zhang, Pengfei; Chiu, Anthony S. F.; Xu, Ming; Yu, Huajun; Meng, Jing; Wang, Yutao
  作者单位：Fudan University; Fudan University; Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS; Nanchang University; University of Tennessee System; University of Tennessee Knoxville; South China University of Technology; Universidade Paulista; Shandong University; De La Salle University; Tsinghua University; University of London; University College London; Fudan University; Fudan University
  摘要：The pulp and paper industry is an important contributor to global greenhouse gas emissions1,2. Country-specific strategies are essential for the industry to achieve net-zero emissions by 2050, given its vast heterogeneities across countries3,4. Here we develop a comprehensive bottom-up assessment of net greenhouse gas emissions of the domestic paper-related sectors for 30 major countries from 1961 to 2019-about 3.2% of global anthropogenic greenhouse gas emissions from the same period5-and exp...
• A glacier's 'memory' is fading because of climate change AI翻译
  作者：[Anonymous]
• 7-Dehydrocholesterol dictates ferroptosis sensitivity AI翻译
  作者：Li, Yaxu; Ran, Qiao; Duan, Qiuhui; Jin, Jiali; Wang, Yanjin; Yu, Lei; Wang, Chaojie; Zhu, Zhenyun; Chen, Xin; Weng, Linjun; Li, Zan; Wang, Jia; Wu, Qi; Wang, Hui; Tian, Hongling; Song, Sihui; Shan, Zezhi; Zhai, Qiwei; Qin, Huanlong; Chen, Shili; Fang, Lan; Yin, Huiyong; Zhou, Hu; Jiang, Xuejun; Wang, Ping
  作者单位：Tongji University; Tongji University; Chinese Academy of Sciences; Shanghai Institute of Materia Medica, CAS; Chinese Academy of Sciences; Shanghai Institute of Nutrition & Health, CAS; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS; University of Chinese Academy of Sciences, CAS; Shanghai Jiao Tong University; City University of Hong Kong; Memorial Sloan Kettering Cancer Center
  摘要：Ferroptosis, a form of regulated cell death that is driven by iron-dependent phospholipid peroxidation, has been implicated in multiple diseases, including cancer1-3, degenerative disorders4 and organ ischaemia-reperfusion injury (IRI)5,6. Here, using genome-wide CRISPR-Cas9 screening, we identified that the enzymes involved in distal cholesterol biosynthesis have pivotal yet opposing roles in regulating ferroptosis through dictating the level of 7-dehydrocholesterol (7-DHC)-an intermediate me...
• No 'easy' weight loss: don't overlook the social cost of anti-obesity drugs AI翻译
  作者：Brewis, Alexandra; Trainer, Sarah
  作者单位：Arizona State University; Arizona State University-Tempe; Arizona State University; Arizona State University-Tempe; Seattle University
• Clinical trials: Japan's opt-out policy raises risks of adverse drug responses AI翻译
  作者：Namba, Mira; Kaneda, Yudai; Ozaki, Akihiko; Tanimoto, Tetsuya
  作者单位：Keio University; Hokkaido University
  摘要：Letter to the Editor
• Where I work Heather Middleton AI翻译
  作者：Pells, Rachael
• Structures, functions and adaptations of the human LINE-1 ORF2 protein AI翻译
  作者：Baldwin, Eric T.; van Eeuwen, Trevor; Hoyos, David; Zalevsky, Arthur; Tchesnokov, Egor P.; Sanchez, Roberto; Miller, Bryant D.; Di Stefano, Luciano H.; Ruiz, Francesc Xavier; Hancock, Matthew; Isik, Esin; Mendez-Dorantes, Carlos; Walpole, Thomas; Nichols, Charles; Wan, Paul; Riento, Kirsi; Halls-Kass, Rowan; Augustin, Martin; Lammens, Alfred; Jestel, Anja; Upla, Paula; Xibinaku, Kera; Congreve, Samantha; Hennink, Maximiliaan; Rogala, Kacper B.; Schneider, Anna M.; Fairman, Jennifer E.; Christensen, Shawn M.; Desrosiers, Brian; Bisacchi, Gregory S.; Saunders, Oliver L.; Hafeez, Nafeeza; Miao, Wenyan; Kapeller, Rosana; Zaller, Dennis M.; Sali, Andrej; Weichenrieder, Oliver; Burns, Kathleen H.; Goette, Matthias; Rout, Michael P.; Arnold, Eddy; Greenbaum, Benjamin D.; Romero, Donna L.; Lacava, John; Taylor, Martin S.
  作者单位：Rockefeller University; Memorial Sloan Kettering Cancer Center; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of Alberta; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard Medical School; University of Groningen; Rutgers University System; Rutgers University New Brunswick; Rutgers University System; Rutgers University New Brunswick; Massachusetts Institute of Technology (MIT); Whitehead Institute; Stanford University; Stanford University; Stanford Cancer Institute; Stanford University; Max Planck Society; Johns Hopkins University; University of Texas System; University of Texas Arlington; Cornell University; Weill Cornell Medicine; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital
  摘要：The LINE-1 (L1) retrotransposon is an ancient genetic parasite that has written around one-third of the human genome through a 'copy and paste' mechanism catalysed by its multifunctional enzyme, open reading frame 2 protein (ORF2p)1. ORF2p reverse transcriptase (RT) and endonuclease activities have been implicated in the pathophysiology of cancer2,3, autoimmunity4,5 and ageing6,7, making ORF2p a potential therapeutic target. However, a lack of structural and mechanistic knowledge has hampered ...
• Bacterial prey turns the tables on predator AI翻译
  作者：Mitchinson, Andrew
• Laser pulses engrave an unlikely surface: soap films AI翻译
  作者：[Anonymous]
• Forget lung, breast or prostate cancer: why tumour naming needs to change AI翻译
  作者：Andre, Fabrice; Rassy, Elie; Marabelle, Aurelien; Michiels, Stefan; Besse, Benjamin
  作者单位：UNICANCER; Gustave Roussy; Universite Paris Saclay; Universite Paris Saclay; Institut National de la Sante et de la Recherche Medicale (Inserm); UNICANCER; Gustave Roussy; UNICANCER; Gustave Roussy; Universite Paris Saclay; Institut National de la Sante et de la Recherche Medicale (Inserm); UNICANCER; Gustave Roussy; Institut National de la Sante et de la Recherche Medicale (Inserm)