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作者：Kwon, Diana
摘要：Half a dozen drugs are in trials for conditions of the brain, but success is not guaranteed.
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作者：Vandekar, Simon
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作者：[Anonymous]
摘要：Analysis of neuroimaging studies shows that close attention to experimental design can increase the statistical robustness of research results.
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作者：Sass, Frederike; Ma, Tao; Ekberg, Jeppe H.; Kirigiti, Melissa; Urena, Mario G.; Dollet, Lucile; Brown, Jenny M.; Basse, Astrid L.; Yacawych, Warren T.; Burm, Hayley B.; Andersen, Mette K.; Nielsen, Thomas S.; Tomlinson, Abigail J.; Dmytiyeva, Oksana; Christensen, Dan P.; Bader, Lindsay; Vo, Camilla T.; Wang, Yaxu; Rausch, Dylan M.; Kristensen, Cecilie K.; Gestal-Mato, Maria; Panhuis, Wietse In Het; Sjoberg, Kim A.; Kernodle, Stace; Petersen, Jacob E.; Pavlovskyi, Artem; Sandhu, Manbir; Moltke, Ida; Jorgensen, Marit E.; Albrechtsen, Anders; Grarup, Niels; Babu, M. Madan; Rensen, Patrick C. N.; Kooijman, Sander; Seeley, Randy J.; Worthmann, Anna; Heeren, Joerg; Pers, Tune H.; Hansen, Torben; Gustafsson, Magnus B. F.; Tang-Christensen, Mads; Kilpelainen, Tuomas O.; Myers Jr, Martin G.; Kievit, Paul; Schwartz, Thue W.; Hansen, Jakob B.; Gerhart-Hines, Zachary
作者单位：University of Copenhagen; University of Southern Denmark; Oregon Health & Science University; Oregon National Primate Research Center; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; St Jude Children's Research Hospital; Leiden University - Excl LUMC; Leiden University; Leiden University Medical Center (LUMC); Leiden University; Leiden University Medical Center (LUMC); Leiden University - Excl LUMC; University of Michigan System; University of Michigan; University of Copenhagen; Steno Diabetes Center; University of Copenhagen; Copenhagen University Hospital; University of Southern Denmark; University of Hamburg; University Medical Center Hamburg-Eppendorf; Monash University
摘要：The combination of decreasing food intake and increasing energy expenditure represents a powerful strategy for counteracting cardiometabolic diseases such as obesity and type 2 diabetes1. Yet current pharmacological approaches require conjugation of multiple receptor agonists to achieve both effects2-4, and so far, no safe energy-expending option has reached the clinic. Here we show that activation of neurokinin 2 receptor (NK2R) is sufficient to suppress appetite centrally and increase energy...
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作者：Li, Shunde; Xiao, Yun; Su, Rui; Xu, Weidong; Luo, Deying; Huang, Pengru; Dai, Linjie; Chen, Peng; Caprioglio, Pietro; Elmestekawy, Karim A.; Dubajic, Milos; Chosy, Cullen; Hu, Juntao; Habib, Irfan; Dasgupta, Akash; Guo, Dengyang; Boeije, Yorrick; Zelewski, Szymon J.; Lu, Zhangyuchang; Huang, Tianyu; Li, Qiuyang; Wang, Jingmin; Yan, Haoming; Chen, Hao-Hsin; Li, Chunsheng; Lewis, Barnaby A. I.; Wang, Dengke; Wu, Jiang; Zhao, Lichen; Han, Bing; Wang, Jianpu; Herz, Laura M.; Durrant, James R.; Novoselov, Kostya S.; Lu, Zheng-Hong; Gong, Qihuang; Stranks, Samuel D.; Snaith, Henry J.; Zhu, Rui
作者单位：Peking University; Peking University; Tsinghua University; Collaborative Innovation Center of Quantum Matter; University of Oxford; University of Cambridge; University of Cambridge; Beihang University; National University of Singapore; Institute for Functional Intelligent Materials (I-FIM); Yunnan University; Wroclaw University of Science & Technology; Nanjing Tech University; Nanjing Tech University; Peking University; Eastern Institute of Technology, Ningbo; Eastern Institute for Advanced Study; Changzhou University; Changzhou University; Imperial College London; Imperial College London; Swansea University; University of Toronto; Shanxi University
摘要：Obtaining micron-thick perovskite films of high quality is key to realizing efficient and stable positive (p)-intrinsic (i)-negative (n) perovskite solar cells1,2, but it remains a challenge. Here we report an effective method for producing high-quality, micron-thick formamidinium-based perovskite films by forming coherent grain boundaries, in which high-Miller-index-oriented grains grow on the low-Miller-index-oriented grains in a stabilized atmosphere. The resulting micron-thick perovskite f...
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作者：[Anonymous]
摘要：Stimulating certain brain cells in mice seems to ease anxiety without causing hallucination-like effects.
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作者：Modi, Gaurav; Parate, Shubham K.; Kwon, Choah; Meng, Andrew C.; Khandelwal, Utkarsh; Tullibilli, Anudeep; Horwath, James; Davies, Peter K.; Stach, Eric A.; Li, Ju; Nukala, Pavan; Agarwal, Ritesh
作者单位：University of Pennsylvania; Indian Institute of Science (IISC) - Bangalore; Massachusetts Institute of Technology (MIT)
摘要：Electrically induced amorphization is uncommon and has so far been realized by pulsed electrical current in only a few material systems, which are mostly based on the melt-quench process1. However, if the melting step can be avoided and solid-state amorphization can be realized electrically, it opens up the possibility for low-power device applications2-5. Here we report an energy-efficient, unconventional long-range solid-state amorphization in a new ferroic beta ''-phase of indium selenide n...
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作者：Driscoll, Don A.; Macdonald, Kristina J.; Gibson, Rebecca K.; Doherty, Tim S.; Nimmo, Dale G.; Nolan, Rachael H.; Ritchie, Euan G.; Williamson, Grant J.; Heard, Geoffrey W.; Tasker, Elizabeth M.; Bilney, Rohan; Porch, Nick; Collett, Rachael A.; Crates, Ross A.; Hewitt, Alison C.; Pendall, Elise; Boer, Matthias M.; Gates, Jody; Boulton, Rebecca L.; Mclean, Christopher M.; Groffen, Heidi; Maisey, Alex C.; Beranek, Chad T.; Ryan, Shelby A.; Callen, Alex; Hamer, Andrew J.; Stauber, Andrew; Daly, Garry J.; Gould, John; Klop-Toker, Kaya L.; Mahony, Michael J.; Kelly, Oliver W.; Wallace, Samantha L.; Stock, Sarah E.; Weston, Christopher J.; Volkova, Liubov; Black, Dennis; Gibb, Heloise; Grubb, Joshua J.; McGeoch, Melodie A.; Murphy, Nick P.; Lee, Joshua S.; Dickman, Chris R.; Neldner, Victor J.; Ngugi, Michael R.; Miritis, Vivianna; Kohler, Frank; Perri, Marc; Denham, Andrew J.; Mackenzie, Berin D. E.; Reid, Chris A. M.; Rayment, Julia T.; Arriaga-Jimenez, Alfonsina; Hewins, Michael W.; Hicks, Andrew; Melbourne, Brett A.; Davies, Kendi F.; Bitters, Matthew E.; Linley, Grant D.; Greenville, Aaron C.; Webb, Jonathan K.; Roberts, Bridget; Letnic, Mike; Price, Owen F.; Walker, Zac C.; Murray, Brad R.; Verhoeven, Elise M.; Thomsen, Alexandria M.; Keith, David; Lemmon, Jedda S.; Ooi, Mark K. J.; Allen, Vanessa L.; Decker, Orsi T.; Green, Peter T.; Moussalli, Adnan; Foon, Junn K.; Bryant, David B.; Walker, Ken L.; Bruce, Matthew J.; Madani, George; Tscharke, Jeremy L.; Wagner, Benjamin; Nitschke, Craig R.; Gosper, Carl R.; Yates, Colin J.; Dillon, Rebecca; Barrett, Sarah; Spencer, Emma E.; Wardle, Glenda M.; Newsome, Thomas M.; Pulsford, Stephanie A.; Singh, Anu; Roff, Adam; Marsh, Karen J.; Mcdonald, Kye; Howell, Lachlan G.; Lane, Murraya R.; Cristescu, Romane H.; Witt, Ryan R.; Cook, Emma J.; Grant, Felicity; Law, Bradley S.; Seddon, Julian; Berris, Karleah K.; Shofner, Ryan M.; Barth, Mike; Welz, Torran; Foster, Alison; Hancock, David; Beitzel, Matthew; Tan, Laura X. L.; Waddell, Nathan A.; Fallow, Pamela M.; Schweickle, Laura; Le Breton, Tom D.; Dunne, Craig; Green, Mikayla; Gilpin, Amy-Marie; Cook, James M.; Power, Sally A.; Hogendoorn, Katja; Brawata, Renee; Jolly, Chris J.; Tozer, Mark; Reiter, Noushka; Phillips, Ryan D.
作者单位：Deakin University; University of Sydney; Charles Sturt University; Western Sydney University; University of Tasmania; University of Queensland; University of Queensland; Australian National University; University of Adelaide; La Trobe University; University of Newcastle; HUN-REN; HUN-REN Centre for Ecological Research; University of Melbourne; University of New South Wales Sydney; Australian Museum; University of Wollongong; University of New England; University of Colorado System; University of Colorado Boulder; University of Technology Sydney; Arthur Rylah Institute for Environmental Research (ARI); University of Melbourne; Bush Heritage Australia; Australian National University; University of the Sunshine Coast; University of Adelaide; University of Canberra; Macquarie University
摘要：With large wildfires becoming more frequent(1,2), we must rapidly learn how megafires impact biodiversity to prioritize mitigation and improve policy. A key challenge is to discover how interactions among fire-regime components, drought and land tenure shape wildfire impacts. The globally unprecedented(3,4) 2019-2020 Australian megafires burnt more than 10 million hectares(5), prompting major investment in biodiversity monitoring. Collated data include responses of more than 2,000 taxa, provid...
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作者：Mallapaty, Smriti
摘要：The largest scholarly search engine is celebrating its 20th birthday, but AI-driven competitors offer advantages.
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作者：Shahandeh, Michael P.; Abuin, Liliane; De Decker, Lou Lescuyer; Cergneux, Julien; Koch, Rafael; Nagoshi, Emi; Benton, Richard
作者单位：University of Lausanne; University of Geneva; University of Geneva; Hofstra University
摘要：Many organisms, including cosmopolitan drosophilids, show circadian plasticity, varying their activity with changing dawn-dusk intervals1. How this behaviour evolves is unclear. Here we compare Drosophila melanogaster with Drosophila sechellia, an equatorial, ecological specialist that experiences minimal photoperiod variation, to investigate the mechanistic basis of circadian plasticity evolution2. D. sechellia has lost the ability to delay its evening activity peak time under long photoperio...
