2024

最新文章

• Meaningfulness in a scientific career is about more than tangible outputs AI翻译
  作者：Alexandrova, Anna
  作者单位：University of Cambridge
  摘要：Letter to the Editor
• Could AI-designed proteins be weaponized? Scientists lay out safety guidelines AI翻译
  作者：Callaway, Ewen
  摘要：AI tools that can come up with protein structures at the push of a button should be used safely and ethically, say researchers in the field.
• So...you've been hacked AI翻译
  作者：Brooks, Michael
  摘要：Research institutions are under siege from cybercriminals and other digital assailants. How do you make sure you don't let them in?
• Non-reciprocal topological solitons in active metamaterials AI翻译
  作者：Veenstra, Jonas; Gamayun, Oleksandr; Guo, Xiaofei; Sarvi, Anahita; Meinersen, Chris Ventura; Coulais, Corentin
  作者单位：University of Amsterdam
  摘要：From protein motifs1 to black holes2, topological solitons are pervasive nonlinear excitations that are robust and can be driven by external fields3. So far, existing driving mechanisms all accelerate solitons and antisolitons in opposite directions3,4. Here we introduce a local driving mechanism for solitons that accelerates both solitons and antisolitons in the same direction instead: non-reciprocal driving. To realize this mechanism, we construct an active mechanical metamaterial consisting...
• Photonic chip-based low-noise microwave oscillator AI翻译
  作者：Kudelin, Igor; Groman, William; Ji, Qing-Xin; Guo, Joel; Kelleher, Megan L.; Lee, Dahyeon; Nakamura, Takuma; Mclemore, Charles A.; Shirmohammadi, Pedram; Hanifi, Samin; Cheng, Haotian; Jin, Naijun; Wu, Lue; Halladay, Samuel; Luo, Yizhi; Dai, Zhaowei; Jin, Warren; Bai, Junwu; Liu, Yifan; Zhang, Wei; Xiang, Chao; Chang, Lin; Iltchenko, Vladimir; Miller, Owen; Matsko, Andrey; Bowers, Steven M.; Rakich, Peter T.; Campbell, Joe C.; Bowers, John E.; Vahala, Kerry J.; Quinlan, Franklyn; Diddams, Scott A.
  作者单位：National Institute of Standards & Technology (NIST) - USA; University of Colorado System; University of Colorado Boulder; California Institute of Technology; University of California System; University of California Santa Barbara; University of Virginia; Yale University; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); California Institute of Technology; University of Colorado System; University of Colorado Boulder
  摘要：Numerous modern technologies are reliant on the low-phase noise and exquisite timing stability of microwave signals. Substantial progress has been made in the field of microwave photonics, whereby low-noise microwave signals are generated by the down-conversion of ultrastable optical references using a frequency comb1-3. Such systems, however, are constructed with bulk or fibre optics and are difficult to further reduce in size and power consumption. In this work we address this challenge by l...
• I study small organisms to tackle big climate problems AI翻译
  作者：Forrester, Nikki; Castro, Gabriel Renato
  摘要：Marine biologist Gabriel Renato Castro cultivates compounds from cyanobacteria to support agriculture and the environment.
• Oxidative cyclization reagents reveal tryptophan cation-π interactions AI翻译
  作者：Xie, Xiao; Moon, Patrick J.; Crossley, Steven W. M.; Bischoff, Amanda J.; He, Dan; Li, Gen; Dao, Nam; Gonzalez-Valero, Angel; Reeves, Audrey G.; McKenna, Jeffrey M.; Elledge, Susanna K.; Wells, James A.; Toste, F. Dean; Chang, Christopher J.
  作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Novartis; Novartis USA; University of California System; University of California San Francisco; University of California System; University of California San Francisco
  摘要：Methods for selective covalent modification of amino acids on proteins can enable a diverse array of applications, spanning probes and modulators of protein function to proteomics(1, 2-3). Owing to their high nucleophilicity, cysteine and lysine residues are the most common points of attachment for protein bioconjugation chemistry through acid-base reactivity(3,4). Here we report a redox-based strategy for bioconjugation of tryptophan, the rarest amino acid, using oxaziridine reagents that mim...
• China's medical-device industry gets a makeover AI翻译
  作者：Ong, Sandy
  摘要：The country is keen to boost its production of medical technology to reduce its reliance on imports. Analysts discuss the impact of policies.
• Climate models can't explain 2023's huge heat anomaly - we could be in uncharted territory AI翻译
  作者：Schmidt, Gavin
  作者单位：National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Goddard Institute for Space Studies
  摘要：Taking into account all known factors, the planet warmed 0.2 degrees C more last year than climate scientists expected. More and better data are urgently needed.
• Bumblebees socially learn behaviour too complex to innovate alone AI翻译
  作者：Bridges, Alice D.; Royka, Amanda; Wilson, Tara; Lockwood, Charlotte; Richter, Jasmin; Juusola, Mikko; Chittka, Lars
  作者单位：University of London; Queen Mary University London; University of Sheffield; University of Sheffield; Yale University
  摘要：Culture refers to behaviours that are socially learned and persist within a population over time. Increasing evidence suggests that animal culture can, like human culture, be cumulative: characterized by sequential innovations that build on previous ones1. However, human cumulative culture involves behaviours so complex that they lie beyond the capacity of any individual to independently discover during their lifetime1-3. To our knowledge, no study has so far demonstrated this phenomenon in an...