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作者:Lenharo, Mariana
摘要:Machine-learning system trained on millions of human audio clips shows promise for detecting COVID-19 and tuberculosis.
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作者:Mitchard, Edward; Ellis, Peter; Patton, Susan Cook; Adjei, Roselyn Fosuah
作者单位:Nature Conservancy
摘要:Letter to the Editor
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作者:Kelvington, Benjamin A.; Abel, Ted
作者单位:University of Iowa
摘要:A population of neurons that engages mechanisms of the innate immune system during memory formation has been uncovered in mice. Surprisingly, inflammatory signalling might pave the way for long-term memory.
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作者:Docter-Loeb, Hannah
摘要:As X wanes, researchers are turning to Reddit for insights and data, and to better connect with the public.
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作者:Odgers, Candice L.
作者单位:University of California System; University of California Irvine
摘要:The evidence is equivocal on whether screen time is to blame for rising levels of teen depression and anxiety - and rising hysteria could distract us from tackling the real causes.
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作者:Zhang, Binbin; Li, Jiyu; Zhou, Jingkun; Chow, Lung; Zhao, Guangyao; Huang, Ya; Ma, Zhiqiang; Zhang, Qiang; Yang, Yawen; Yiu, Chun Ki; Li, Jian; Chun, Fengjun; Huang, Xingcan; Gao, Yuyu; Wu, Pengcheng; Jia, Shengxin; Li, Hu; Li, Dengfeng; Liu, Yiming; Yao, Kuanming; Shi, Rui; Chen, Zhenlin; Khoo, Bee Luan; Yang, Weiqing; Wang, Feng; Zheng, Zijian; Wang, Zuankai; Yu, Xinge
作者单位:City University of Hong Kong; City University of Hong Kong; Southwest Jiaotong University; Hong Kong Polytechnic University; Hong Kong Polytechnic University
摘要:Wearable electronics with great breathability enable a comfortable wearing experience and facilitate continuous biosignal monitoring over extended periods1-3. However, current research on permeable electronics is predominantly at the stage of electrode and substrate development, which is far behind practical applications with comprehensive integration with diverse electronic components (for example, circuitry, electronics, encapsulation)4-8. Achieving permeability and multifunctionality in a s...
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作者:Ross, Jason B.; Myers, Lara M.; Noh, Joseph J.; Collins, Madison M.; Carmody, Aaron B.; Messer, Ronald J.; Dhuey, Erica; Hasenkrug, Kim J.; Weissman, Irving L.
作者单位:Stanford University; Stanford University; Stanford University; Stanford Cancer Institute; Stanford University; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Stanford University; Montana State University System; Montana State University Billings; Montana State University Bozeman
摘要:Ageing of the immune system is characterized by decreased lymphopoiesis and adaptive immunity, and increased inflammation and myeloid pathologies(1,2). Age-related changes in populations of self-renewing haematopoietic stem cells (HSCs) are thought to underlie these phenomena(3). During youth, HSCs with balanced output of lymphoid and myeloid cells (bal-HSCs) predominate over HSCs with myeloid-biased output (my-HSCs), thereby promoting the lymphopoiesis required for initiating adaptive immune ...
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作者:Shioi, Takuro; Hatazawa, Suguru; Oya, Eriko; Hosoya, Noriko; Kobayashi, Wataru; Ogasawara, Mitsuo; Kobayashi, Takehiko; Takizawa, Yoshimasa; Kurumizaka, Hitoshi
作者单位:University of Tokyo; University of Tokyo; University of Tokyo; University of Tokyo
摘要:RAD51 is the central eukaryotic recombinase required for meiotic recombination and mitotic repair of double-strand DNA breaks (DSBs)(1,2). However, the mechanism by which RAD51 functions at DSB sites in chromatin has remained elusive. Here we report the cryo-electron microscopy structures of human RAD51-nucleosome complexes, in which RAD51 forms ring and filament conformations. In the ring forms, the N-terminal lobe domains (NLDs) of RAD51 protomers are aligned on the outside of the RAD51 ring...
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作者:Han, Guangchun; Sinjab, Ansam; Rahal, Zahraa; Lynch, Anne M.; Treekitkarnmongkol, Warapen; Liu, Yuejiang; Serrano, Alejandra G.; Feng, Jiping; Liang, Ke; Khan, Khaja; Lu, Wei; Hernandez, Sharia D.; Liu, Yunhe; Cao, Xuanye; Dai, Enyu; Pei, Guangsheng; Hu, Jian; Abaya, Camille; Gomez-Bolanos, Lorena I.; Peng, Fuduan; Chen, Minyue; Parra, Edwin R.; Cascone, Tina; Sepesi, Boris; Moghaddam, Seyed Javad; Scheet, Paul; Negrao, Marcelo V.; Heymach, John V.; Li, Mingyao; Dubinett, Steven M.; Stevenson, Christopher S.; Spira, Avrum E.; Fujimoto, Junya; Solis, Luisa M.; Wistuba, Ignacio I.; Chen, Jichao; Wang, Linghua; Kadara, Humam
作者单位:University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; Baylor College of Medicine; University of Pennsylvania; University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; University of California System; University of California Los Angeles; Johnson & Johnson; Johnson & Johnson USA; Boston University
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作者:Delgado-Ramos, Gian C.; Lucatello, Simone; Ley, Debora; Ivanova, Antonina; Romo-Aguilar, Ma de Lourdes; Conde, Cecilia; Imaz-Lamadrid, Miguel
作者单位:Universidad Nacional Autonoma de Mexico; Universidad Autonoma de Baja California; Universidad Autonoma de Baja California; Universidad Nacional Autonoma de Mexico; Universidad Autonoma de Baja California
摘要:Hurricane Otis yields lessons for researchers and policymakers on how to reduce risks in the face of inequality.