8063期

最新文章

• Blood of man who's had 200 snake bites helps make a potent antivenom AI翻译
  作者：Bourzac, Katherine
• How science and international cooperation closed the ozone hole AI翻译
  作者：[Anonymous]
• Highly sensitive method captures rare RNAs in blood to search for disease AI翻译
  作者：Rounge, Trine B.; Paulsen, Jonas
  作者单位：University of Oslo; University of Oslo; Norwegian Institute of Public Health (NIPH); University of Oslo
• A Jurassic acanthocephalan illuminates the origin of thorny-headed worms AI翻译
  作者：Luo, Cihang; Parry, Luke A.; Boudinot, Brendon E.; Wang, Shengyu; Jarzembowski, Edmund A.; Zhang, Haichun; Wang, Bo
  作者单位：Chinese Academy of Sciences; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Leibniz Association; Senckenberg Gesellschaft fur Naturforschung (SGN); University of Oxford; Natural History Museum London
  摘要：Acanthocephala (thorny-headed worms), characterized by the presence of an eversible proboscis with hooks, are a diverse endoparasitic group that infect a wide range of vertebrates and invertebrates1. Although long regarded as a separate phylum, they have several putative sister taxa based on morphological features, including Platyhelminthes (flatworms)2, Priapulida (penis worms)3 and Rotifera (wheel animals)4. Molecular phylogenies have instead recovered them within rotifers5, 6, 7, 8, 9-10, s...
• irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA AI翻译
  作者：Ducoli, Luca; Zarnegar, Brian J.; Porter, Douglas F.; Meyers, Robin M.; Miao, Weili; Riley, Nicholas M.; Srinivasan, Suhas; Jackrazi, Leandra V.; Yang, Yen-Yu; Li, Zhouxian; Wang, Yinsheng; Bertozzi, Carolyn R.; Flynn, Ryan A.; Khavari, Paul A.
  作者单位：Stanford University; Stanford University; Howard Hughes Medical Institute; Stanford University; University of California System; University of California Riverside; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard University; Stanford University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Palo Alto Health Care System
  摘要：RNA-binding proteins (RBPs) control varied processes, including RNA splicing, stability, transport and translation1, 2-3. Dysfunctional RNA-RBP interactions contribute to the pathogenesis of human disease1,4,5; however, characterizing the nature and dynamics of multiprotein assemblies on RNA has been challenging. Here, to address this, non-isotopic ligation-based ultraviolet-light-induced cross-linking and immunoprecipitation6 was combined with mass spectrometry (irCLIP-RNP) to identify RNA-de...
• Wireless transmission of internal hazard signals in Li-ion batteries AI翻译
  作者：Fan, Jinbao; Liu, Chenchen; Li, Na; Yang, Le; Yang, Xiao-Guang; Dou, Bowen; Hou, Shujuan; Feng, Xuning; Jiang, Hanqing; Li, Hong; Song, Wei-Li; Sun, Lei; Chen, Hao-Sen; Gao, Huajian; Fang, Daining
  作者单位：Beijing Institute of Technology; University of Science & Technology Beijing; Beijing Institute of Technology; Beijing Institute of Technology; Tsinghua University; Westlake University; Chinese Academy of Sciences; Institute of Physics, CAS; Beijing Institute of Technology; Tsinghua University
  摘要：High-capacity lithium-ion batteries (LIBs) play a critical role as power sources across diverse applications, including portable electronics, electric vehicles (EVs) and renewable-energy-storage systems1. However, there is growing concern about the safety of integrated LIB systems, with reports of up to 9,486 incidents between 2020 and 2024 (ref. 2). To ensure the safe application of commercial LIBs, it is essential to capture internal signals that enable early failure diagnosis and warning. M...
• Earth's climatic past illuminates future South Asian monsoon patterns AI翻译
  作者：Pausata, Francesco S. R.; Tharammal, Thejna
  作者单位：University of Quebec; University of Quebec Montreal; University of Quebec; University of Quebec Montreal; Indian Institute of Science (IISC) - Bangalore
• Emergence of Calabi-Yau manifolds in high-precision black-hole scattering AI翻译
  作者：Driesse, Mathias; Jakobsen, Gustav Uhre; Klemm, Albrecht; Mogull, Gustav; Nega, Christoph; Plefka, Jan; Sauer, Benjamin; Usovitsch, Johann
  作者单位：Humboldt University of Berlin; Max Planck Society; University of Bonn; University of Bonn; University of London; Queen Mary University London; University College London; Technical University of Munich
  摘要：When two massive objects (black holes, neutron stars or stars) in our universe fly past each other, their gravitational interactions deflect their trajectories1,2. The gravitational waves emitted in the related bound-orbit system-the binary inspiral-are now routinely detected by gravitational-wave observatories3. Theoretical physics needs to provide high-precision templates to make use of unprecedented sensitivity and precision of the data from upcoming gravitational-wave observatories4. Motiv...
• An ultrasensitive method for detection of cell-free RNA AI翻译
  作者：Nesselbush, Monica C.; Luca, Bogdan A.; Jeon, Young-Jun; Jabara, Isabel; Meador, Catherine B.; Garofalo, Andrea; Binkley, Michael S.; Hui, Angela B.; van 't Erve, Iris; Xu, Nova; Shi, William Y.; Liu, Kevin J.; Sugio, Takeshi; Kastelowitz, Noah; Hamilton, Emily G.; Liu, Chih Long; Olsen, Mari; Bonilla, Rene F.; Wang, Yi Peng; Jiang, Alice; Lau, Brianna; Eichholz, Jordan; Banwait, Mandeep; Schroers-Martin, Joseph; Boegeholz, Jan; King, Daniel A.; Luikart, Helen; Esfahani, Mohammad S.; Mehrmohamadi, Mahya; Stehr, Henning; Raclin, Tyler; Tibshirani, Robert; Khush, Kiran; Srinivas, Sandy; Yu, Helena; Rogers, Angela J.; Nair, Viswam S.; Isbell, James M.; Li, Bob T.; Piotrowska, Zofia; Sequist, Lecia V.; Hata, Aaron N.; Neal, Joel W.; Wakelee, Heather A.; Gentles, Andrew J.; Alizadeh, Ash A.; Diehn, Maximilian
  作者单位：Stanford University; Stanford Cancer Institute; Stanford University; Stanford University; Stanford University; Sungkyunkwan University (SKKU); Stanford University; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Stanford University; Memorial Sloan Kettering Cancer Center; Stanford University; Stanford University; Stanford University; Memorial Sloan Kettering Cancer Center; Stanford University; Fred Hutchinson Cancer Center; University of Washington; University of Washington Seattle; Memorial Sloan Kettering Cancer Center; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Stanford University
  摘要：Sensitive methods for detection of cell-free RNA (cfRNA) could facilitate non-invasive gene expression profiling and monitoring of diseases1, 2, 3, 4, 5-6. Here we describe RARE-seq (random priming and affinity capture of cfRNA fragments for enrichment analysis by sequencing), a method optimized for cfRNA analysis. We demonstrate that platelet contamination can substantially confound cfRNA analyses and develop an approach to overcome it. In analytical validations, we find RARE-seq to be approx...
• Basis functions for complex social decisions in dorsomedial frontal cortex AI翻译
  作者：Wittmann, Marco K.; Lin, Yongling; Pan, Deng; Braun, Moritz N.; Dickson, Cormac; Spiering, Lisa; Luo, Shuyi; Harbison, Caroline; Abdurahman, Ayat; Hamilton, Sorcha; Faber, Nadira S.; Khalighinejad, Nima; Lockwood, Patricia L.; Rushworth, Matthew F. S.
  作者单位：University of London; University College London; University of London; University College London; University of Oxford; Beijing Normal University; Saarland University; University of Oxford; University of Bath; University of Bremen; University of Oxford; University of Birmingham; University of Birmingham; University of Oxford
  摘要：Navigating social environments is a fundamental challenge for the brain. It has been established that the brain solves this problem, in part, by representing social information in an agent-centric manner; knowledge about others' abilities or attitudes is tagged to individuals such as 'oneself' or the 'other'1, 2, 3, 4, 5-6. This intuitive approach has informed the understanding of key nodes in the social parts of the brain, the dorsomedial prefrontal cortex (dmPFC) and the anterior cingulate c...