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作者：[Anonymous]
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作者：Shi, Xianxian; Wen, Zhilin; Gu, Qingqing; Jiao, Long; Jiang, Hai-Long; Lv, Haifeng; Wang, Hengwei; Ding, Jiani; Lyons, Mason P.; Chang, Alvin; Feng, Zhenxing; Chen, Si; Lin, Yue; Xu, Xiaoyan; Du, Pengfei; Xu, Wenlong; Sun, Mei; Li, Yin; Yang, Bing; Zhang, Tao; Wu, Xiaojun; Lu, Junling
作者单位：Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; National University of Defense Technology - China; Chinese Academy of Sciences; Dalian Institute of Chemical Physics, CAS; Oregon State University; Oregon State University; Hefei National Laboratory; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Suzhou Laboratory
摘要：Single-atom catalysts (SACs) with maximized metal use and discrete energy levels hold promise for broad applications in heterogeneous catalysis, energy conversion, environmental science and biomedicine1, 2, 3, 4, 5, 6-7. The activity and stability of SACs are governed by the pair of metal-adsorbate and metal-support interactions8, 9-10. However, the understanding of these interactions with their catalytic performance in nature is challenging. Correlations of activity with the charge state of m...
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作者：Giovanniello, Jacqueline R.; Paredes, Natalie; Wiener, Anna; Ramirez-Armenta, Kathia; Oragwam, Chukwuebuka; Uwadia, Hanniel O.; Yu, Abigail L.; Lim, Kayla; Pimenta, Jenna S.; Vilchez, Gabriela E.; Nnamdi, Gift; Wang, Alicia; Sehgal, Megha; Reis, Fernando M. C., V; Sias, Ana C.; Silva, Alcino J.; Adhikari, Avishek; Malvaez, Melissa; Wassum, Kate M.
作者单位：University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles
摘要：Chronic stress can change how we learn and, thus, how we make decisions1, 2, 3, 4-5. Here we investigated the neuronal circuit mechanisms that enable this. Using a multifaceted systems neuroscience approach in male and female mice, we reveal a dual-pathway, amygdala-striatal neuronal circuit architecture by which a recent history of chronic stress disrupts the action-outcome learning underlying adaptive agency and promotes the formation of inflexible habits. We found that the projection from t...
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作者：Archer, Matthew; Wang, Jinbo; Klein, Patrice; Dibarboure, Gerald; Fu, Lee-Lueng
作者单位：California Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); Texas A&M University System; Texas A&M University College Station; California Institute of Technology; Institut Polytechnique de Paris; Ecole Polytechnique; Sorbonne Universite; Ecole des Ponts ParisTech; Universite PSL; Ecole Normale Superieure (ENS)
摘要：Ocean submesoscale (1-100 km) processes and their substantial impact on Earth's climate system have been increasingly emphasized in recent decades by high-resolution numerical models and regional observations1, 2, 3, 4, 5, 6, 7, 8, 9, 10-11. However, the dynamics and energy associated with these processes, including submesoscale eddies and nonlinear internal waves, have never been observed from a global perspective. Where, when and how much do these submesoscale processes contribute to the lar...
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作者：Maji, Arun; Burke, Martin D.
作者单位：University of Kentucky; University of Illinois System; University of Illinois Urbana-Champaign
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作者：Fletcher Jr, Robert J.
作者单位：University of Cambridge
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作者：Zhi, Xiaofei; Wu, Feijing; Qian, Jin; Ochiai, Yosuke; Lian, Guodong; Malagola, Ermanno; Zheng, Biyun; Tu, Ruhong; Zeng, Yi; Kobayashi, Hiroki; Xia, Zhangchuan; Wang, Ruizhi; Peng, Yueqing; Shi, Qiongyu; Chen, Duan; Ryeom, Sandra W.; Wang, Timothy C.
作者单位：Columbia University; Nantong University; Fujian Medical University; Columbia University; NewYork-Presbyterian Hospital; Columbia University; Columbia University; Norwegian University of Science & Technology (NTNU); Columbia University; NewYork-Presbyterian Hospital
摘要：Cancer cells have been shown to exploit neurons to modulate their survival and growth, including through the establishment of neural circuits within the central nervous system1, 2-3. Here we report a distinct pattern of cancer-nerve interactions between the peripheral nervous system and gastric cancer. In multiple mouse models of gastric cancer, nociceptive nerves demonstrated the greatest degree of nerve expansion in an NGF-dependent manner. Neural tracing identified CGRP+ peptidergic neurons...
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作者：Meza, Arismel Tena; Rivera, Christina A.; Shao, Huiling; Kelleghan, Andrew V.; Houk, K. N.; Garg, Neil K.
作者单位：University of California System; University of California Los Angeles
摘要：The development of new synthetic methodologies is instrumental for enabling the discovery of new medicines. The methods that provide efficient access to structural alternatives for aromatic compounds (that is, saturated arene bioisosteres) have become highly coveted1, 2, 3-4. The incorporation of these bioisosteres typically leads to favourable drug-like properties and represents an emerging field of research. Here we report a new synthetic method that furnishes a coveted motif, the bicyclo[2....
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作者：Garisto, Dan
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作者：Hafner, Danijar; Pasukonis, Jurgis; Ba, Jimmy; Lillicrap, Timothy
作者单位：Alphabet Inc.; DeepMind; University of Toronto
摘要：Developing a general algorithm that learns to solve tasks across a wide range of applications has been a fundamental challenge in artificial intelligence. Although current reinforcement-learning algorithms can be readily applied to tasks similar to what they have been developed for, configuring them for new application domains requires substantial human expertise and experimentation(1,2). Here we present the third generation of Dreamer, a general algorithm that outperforms specialized methods ...
