Science

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• White House defangs NSF watchdog unit AI翻译
  作者：Mervis, Jeffrey
• How making art freed my science AI翻译
  作者：Liu, Shelley H.
  作者单位：Icahn School of Medicine at Mount Sinai
• Tuft dendrites in frontal motor cortex enable flexible learning AI翻译
  作者：Maristany de las Casas, Eduardo; Killmann, Kris; Druke, Moritz; Munster, Lukas; Ebner, Christian; Sachdev, Robert; Jaeger, Dieter; Larkum, Matthew E.
  作者单位：Humboldt University of Berlin; University of Hamburg; University Medical Center Hamburg-Eppendorf; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Emory University
• Sea ice artificially thickened, but concept may not scale AI翻译
  作者：Richter, Hannah
• Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape AI翻译
  作者：Springstein, Benjamin L.; Javoor, Manjunath G.; Megrian, Daniela; Hajdu, Roman; Hanke, Dustin M.; Zens, Bettina; Weiss, Gregor L.; Schur, Florian K. M.; Loose, Martin
  作者单位：Institute of Science & Technology - Austria; Pasteur Network; Institut Pasteur de Montevideo; University of Kiel; University of Zurich
  摘要：Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low-copy number plasmids. In multicellular cyanobacteria such as Anabaena sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal system named CorMR with a function in cell shape control rather than DNA segregation. Live-cell imaging, in vitro reconstitution, and cryo-electron microscopy reveale...
• Cumulative pressures threaten the Red Sea AI翻译
  作者：Adombi, Adoubi Vincent De Paul; Yaseen, Zaher Mundher
  作者单位：University of Quebec; University of Quebec Chicoutimi; King Fahd University of Petroleum & Minerals
• Protein and genomic language models uncover the unexplored diversity of bacterial immunity AI翻译
  作者：Mordret, Ernest; Herve, Alexandre; Tesson, Florian; Vaysset, Hugo; Clabby, Tyler; Loubat, Arthur; Shomar, Helena; Planel, Remi; Lavenir, Rachel; Cury, Jean; Bernheim, Aude
  作者单位：Universite Paris Cite; Pasteur Network; Centre National de la Recherche Scientifique (CNRS); Institut Pasteur Paris; CNRS - National Institute for Biology (INSB); Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; AgroParisTech; Universite Paris Saclay; Universite Paris Cite; Pasteur Network; Institut Pasteur Paris
  摘要：The bacterial pangenome contains a vast diversity of antiphage systems, whose overall extent is still unknown. In this study, we developed complementary machine learning approaches to systematically predict antiphage function from genomic context, protein sequence, or their combination, achieving up to 99% precision and 92% recall. We validated these models experimentally in Escherichia and Streptomyces with the discovery of 12 antiphage systems. Applied to over 32,000 bacterial genomes, these...
• 'Morning sickness hormone' may help reduce alcohol intake AI翻译
  作者：Offord, Catherine
• First science from private Moon lander challenges picture of lunar volcanism AI翻译
  作者：Voosen, Paul
• A global methane observation system to track climate feedbacks for verifiable climate impact AI翻译
  作者：Watts, Jennifer D.; Ordway, Elsa; Malone, Sparkle L.; Zhu, Qing; Palmer, Paul I.; Patel-Tupper, Dhruv; Ciais, Philippe; Li, Fa; Monteverde, Danielle R.; Arndt, Kyle A.; Bruhwiler, Lori; Buma, Brian; Cadillo-Quiroz, Hinsby; Euskirchen, Eugenie; Hoyt, Alison M.; Holgerson, Meredith; Hugelius, Gustaf; Jackson, Robert B.; Jacob, Daniel; Kuhn, Mckenzie; Natali, Susan M.; Peng, Shushi; Perryman, Clarice R.; Poulter, Benjamin; Rey-Sanchez, Camilo; Sagang, Le Bienfaiteur; Schuur, Edward A. G.; Varner, Ruth K.; Vargas, Rodrigo
  作者单位：University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Yale University; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of Edinburgh; Universite Paris Saclay; University of Texas System; University of Texas Austin; National Oceanic Atmospheric Admin (NOAA) - USA; Environmental Defense Fund; Arizona State University; Arizona State University-Tempe; University of Alaska System; University of Alaska Fairbanks; University of Alaska System; University of Alaska Fairbanks; Stanford University; Cornell University; Stockholm University; Harvard University; University of British Columbia; Peking University; North Carolina State University; Northern Arizona University; University System Of New Hampshire; University of New Hampshire; Stockholm University