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作者:Zou, Yimin; Poo, Mu-Ming; Tessier-Lavigne, Marc
作者单位:University of California System; University of California San Diego; Chinese Academy of Sciences; Stanford University
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作者:Lee, Brian K.; Mayhew, Emily J.; Sanchez-Lengeling, Benjamin; Wei, Jennifer N.; Qian, Wesley W.; Little, Kelsie A.; Andres, Matthew; Nguyen, Britney B.; Moloy, Theresa; Yasonik, Jacob; Parker, Jane K.; Gerkin, Richard C.; Mainland, Joel D.; Wiltschko, Alexander B.
作者单位:Alphabet Inc.; Google Incorporated; Monell Chemical Senses Center; Michigan State University; University of Illinois System; University of Illinois Urbana-Champaign; University of Reading; Arizona State University; Arizona State University-Tempe; University of Pennsylvania
摘要:Mapping molecular structure to odor perception is a key challenge in olfaction. We used graph neural networks to generate a principal odor map (POM) that preserves perceptual relationships and enables odor quality prediction for previously uncharacterized odorants. The model was as reliable as a human in describing odor quality: On a prospective validation set of 400 out-of-sample odorants, the model-generated odor profile more closely matched the trained panel mean than did the median panelis...
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作者:Speakman, John R.; Sorensen, Thorkild I. A.; Hall, Kevin D.; Allison, David B.
作者单位:Chinese Academy of Sciences; Shenzhen Institute of Advanced Technology, CAS; University of Aberdeen; Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; China Medical University; University of Copenhagen; University of Copenhagen; Novo Nordisk Foundation; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK); Indiana University System; Indiana University Bloomington
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作者:Tran, Huy Cuong; Schmitt, Vivian; Lama, Sbatie; Wang, Chuande; Launay-Avon, Alexandra; Bernfur, Katja; Sultan, Kristin; Khan, Kasim; Brunaud, Veronique; Liehrmann, Arnaud; Castandet, Benoit; Levander, Fredrik; Rasmusson, Allan G.; Mireau, Hakim; Delannoy, Etienne; Van Aken, Olivier
作者单位:Lund University; Universite Paris Saclay; INRAE; AgroParisTech; Universite Paris Saclay; INRAE; Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); Universite Paris Saclay; INRAE; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Lund University; Lund University; Centre National de la Recherche Scientifique (CNRS); Universite Paris Saclay; Lund University; Swedish University of Agricultural Sciences
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作者:Amstrup, Steven C.; Bitz, Cecilia M.
作者单位:University of Wyoming; University of Washington; University of Washington Seattle
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作者:Shi, Limiao; Boulegue-Mondiere, Aurelie; Blanc, Delphine; Baceiredo, Antoine; Branchadell, Vicenc; Kato, Tsuyoshi
作者单位:Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Centre National de la Recherche Scientifique (CNRS); Autonomous University of Barcelona
摘要:A long-standing problem associated with silicone synthesis is contamination of the polymer products with 10 to 15% cyclic oligosiloxanes that results from backbiting reactions at the polymer chain ends. This process, in competition with chain propagation through ring-opening polymerization (ROP) of cyclic monomers, was thought to be unavoidable and routinely leads to a thermodynamically controlled reaction mixture (polymer/cyclic oligosiloxanes = 85/15). Here, we report that simple alcohol coo...
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作者:Pennisi, Elizabeth
摘要:y
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作者:Nishimura, Takeshi; Mori, Shogo; Shikata, Hiromasa; Nakamura, Moritaka; Hashiguchi, Yasuko; Abe, Yoshinori; Hagihara, Takuma; Yoshikawa, Hiroshi Y.; Toyota, Masatsugu; Higaki, Takumi; Morita, Miyo Terao
作者单位:National Institutes of Natural Sciences (NINS) - Japan; National Institute for Basic Biology (NIBB); Graduate University for Advanced Studies - Japan; Nagoya University; Saitama University; University of Osaka; Suntory Holdings Ltd; University of Wisconsin System; University of Wisconsin Madison; Kumamoto University; Kumamoto University
摘要:Organisms have evolved under gravitational force, and many sense the direction of gravity by means of statoliths in specialized cells. In flowering plants, starch-accumulating plastids, known as amyloplasts, act as statoliths to facilitate downstream gravitropism. The gravity-sensing mechanism has long been considered a mechanosensing process by which amyloplasts transmit forces to intracellular structures, but the molecular mechanism underlying this has not been elucidated. We show here that ...
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作者:Wickelgren, Ingrid
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作者:Leslie, Mitch