Cell polarity linked to gravity sensing is generated by LZY translocation from statoliths to the plasma membrane

• 成果类型: Article
• 署名作者: Nishimura, Takeshi; Mori, Shogo; Shikata, Hiromasa; Nakamura, Moritaka; Hashiguchi, Yasuko; Abe, Yoshinori; Hagihara, Takuma; Yoshikawa, Hiroshi Y.; Toyota, Masatsugu; Higaki, Takumi; Morita, Miyo Terao
• 署名单位: National Institutes of Natural Sciences (NINS) - Japan; National Institute for Basic Biology (NIBB); Graduate University for Advanced Studies - Japan; Nagoya University; Saitama University; University of Osaka; Suntory Holdings Ltd; University of Wisconsin System; University of Wisconsin Madison; Kumamoto University; Kumamoto University
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-10831
• DOI: 10.1126/science.adh9978
• 发表日期: 2023-09-01
• 页码: 1006-1010
• 关键词: root-system architecture; d6 protein-kinase; auxin transport; shoot gravitropism; altered response; arabidopsis; lazy1; DYNAMICS; signal; identification

摘要

Organisms have evolved under gravitational force, and many sense the direction of gravity by means of statoliths in specialized cells. In flowering plants, starch-accumulating plastids, known as amyloplasts, act as statoliths to facilitate downstream gravitropism. The gravity-sensing mechanism has long been considered a mechanosensing process by which amyloplasts transmit forces to intracellular structures, but the molecular mechanism underlying this has not been elucidated. We show here that LAZY1-LIKE (LZY) family proteins involved in statocyte gravity signaling associate with amyloplasts and the proximal plasma membrane. This results in polar localization according to the direction of gravity. We propose a gravity-sensing mechanism by which LZY translocation to the plasma membrane signals the direction of gravity by transmitting information on the position of amyloplasts.