作者：Kite, Edwin S.; Tutolo, Benjamin M.; Turner, Madison L.; Franz, Heather B.; Burtt, David G.; Bristow, Thomas F.; Fischer, Woodward W.; Milliken, Ralph E.; Fraeman, Abigail A.; Zhou, Daniel Y.
作者单位：University of Chicago; University of Calgary; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; National Aeronautics & Space Administration (NASA); NASA Ames Research Center; California Institute of Technology; Brown University; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); California Institute of Technology
摘要：The cause of Mars's loss of surface habitability is unclear, with isotopic data suggesting a 'missing sink' of carbonate1. Past climates with surface and shallow-subsurface liquid water are recorded by Mars's sedimentary rocks, including strata in the approximately 4-km-thick record at Gale Crater2. Those waters were intermittent, spatially patchy and discontinuous, and continued remarkably late in Mars's history3-attributes that can be understood if, as on Earth, sedimentary-rock formation se...
作者：Chen, Xingyu; Shen, Yiling; Choi, Suhyeon; Abdel-Hafiz, Hany A.; Basu, Mukta; Hoelzen, Lena; Tufano, Martina; Kailasam Mani, Saravana Kumar; Ranjpour, Maryam; Zhu, Jiani; Ramanujan, V. Krishnan; Koltsova, Ekaterina K.; Calsavara, Vinicius F.; Knott, Simon R. V.; Theodorescu, Dan
作者单位：Cedars Sinai Medical Center; Cedars Sinai Medical Center; Tsinghua University; Cedars Sinai Medical Center; Cedars Sinai Medical Center; Cedars Sinai Medical Center; Cedars Sinai Medical Center; Johns Hopkins University; University of Arizona
摘要：Loss of the Y chromosome (LOY) in peripheral blood mononuclear cells (PBMCs) is the most common somatic alteration in men and is associated with higher mortality from epithelial cancers1, 2-3. In tumours, epithelial LOY is also associated with poor survival4, 5, 6-7. This raises several fundamental questions, such as why LOY in PBMCs drives cancer mortality and whether there is a relationship between LOY in PBMCs, PBMC-derived immune cells and cancer cells (and, if so, what its consequences ar...
作者：Milojevic, Stasa
作者单位：Indiana University System; Indiana University Bloomington
