Nature

最新文章

• HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor AI翻译
  作者：Fu, Liran; Weiskopf, Erika N.; Akkermans, Onno; Swanson, Nicholas A.; Cheng, Shiya; Schwartz, Thomas U.; Goerlich, Dirk
  作者单位：Massachusetts Institute of Technology (MIT)
  摘要：HIV-1 infection requires nuclear entry of the viral genome. Previous evidence suggests that this entry proceeds through nuclear pore complexes (NPCs), with the 120 x 60 nm capsid squeezing through an approximately 60-nm-wide central channel1 and crossing the permeability barrier of the NPC. This barrier can be described as an FG phase2 that is assembled from cohesively interacting phenylalanine-glycine (FG) repeats3 and is selectively permeable to cargo captured by nuclear transport receptors ...
• The Living City: Why Cities Don't Need to Be Green to Be Great AI翻译
  作者：McPhearson, Timon
  作者单位：The New School
• A 3D nanoscale optical disk memory with petabit capacity AI翻译
  作者：Zhao, Miao; Wen, Jing; Hu, Qiao; Wei, Xunbin; Zhong, Yu-Wu; Ruan, Hao; Gu, Min
  作者单位：Chinese Academy of Sciences; Shanghai Institute of Optics & Fine Mechanics, CAS; University of Shanghai for Science & Technology; Peking University; Anhui Medical University; Chinese Academy of Sciences; Institute of Chemistry, CAS; University of Shanghai for Science & Technology; Zhangjiang Laboratory
  摘要：High-capacity storage technologies are needed to meet our ever-growing data demands1,2. However, data centres based on major storage technologies such as semiconductor flash devices and hard disk drives have high energy burdens, high operation costs and short lifespans2,3. Optical data storage (ODS) presents a promising solution for cost-effective long-term archival data storage. Nonetheless, ODS has been limited by its low capacity and the challenge of increasing its areal density4,5. Here, t...
• Stockholm declaration on AI ethics: why others should sign AI翻译
  作者：King, Ross D.; Scassa, Teresa; Kramer, Stefan; Kitano, Hiroaki
  作者单位：University of Cambridge; University of Ottawa; Johannes Gutenberg University of Mainz; Okinawa Institute of Science & Technology Graduate University
  摘要：Letter to the Editor
• Nanotraps boost light intensity for future optical devices AI翻译
  作者：Koshelev, Kirill
  作者单位：Australian National University
  摘要：A method for configuring light-trapping devices promises better optical nanodevices by amplifying light and enhancing the emission efficiency of luminescent nanomaterials - without the need for complex technology upgrades.
• Converting an allocentric goal into an egocentric steering signal AI翻译
  作者：Pires, Peter Mussells; Zhang, Lingwei; Parache, Victoria; Abbott, L. F.; Maimon, Gaby
  作者单位：Rockefeller University; Rockefeller University; Howard Hughes Medical Institute; Columbia University
  摘要：Neuronal signals that are relevant for spatial navigation have been described in many species1-10. However, a circuit-level understanding of how such signals interact to guide navigational behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex that compares internally generated estimates of the heading and goal angles of the fly-both of which are encoded in world-centred (allocentric) coordinates-to generate a body-centred (egocentric) steering signal. ...
• Chinese databases are a boost for rare-disease science AI翻译
  作者：Liu, Haimeng; Liu, Jianguo
  作者单位：Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS; Michigan State University
• Progressive unanchoring of Antarctic ice shelves since 1973 AI翻译
  作者：Miles, Bertie W. J.; Bingham, Robert G.
  作者单位：University of Edinburgh
  摘要：Mass loss of the Antarctic Ice Sheet has been driven primarily by the thinning of the floating ice shelves that fringe the ice sheet1, reducing their buttressing potential and causing land ice to accelerate into the ocean2. Observations of ice-shelf thickness change by satellite altimetry stretch back only to 1992 (refs. 1,3-5) and previous information about thinning remains unquantified. However, extending the record of ice-shelf thickness change is possible by proxy, by measuring the change ...
• An epigenetic barrier sets the timing of human neuronal maturation AI翻译
  作者：Ciceri, Gabriele; Baggiolini, Arianna; Cho, Hyein S.; Kshirsagar, Meghana; Benito-Kwiecinski, Silvia; Walsh, Ryan M.; Aromolaran, Kelly A.; Gonzalez-Hernandez, Alberto J.; Munguba, Hermany; Koo, So Yeon; Xu, Nan; Sevilla, Kaylin J.; Goldstein, Peter A.; Levitz, Joshua; Leslie, Christina S.; Koche, Richard P.; Studer, Lorenz
  作者单位：Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Universita della Svizzera Italiana; Institute of Oncology Research (IOR); Universita della Svizzera Italiana
  摘要：The pace of human brain development is highly protracted compared with most other species1-7. The maturation of cortical neurons is particularly slow, taking months to years to develop adult functions3-5. Remarkably, such protracted timing is retained in cortical neurons derived from human pluripotent stem cells (hPSCs) during in vitro differentiation or upon transplantation into the mouse brain4,8,9. Those findings suggest the presence of a cell-intrinsic clock setting the pace of neuronal ma...
• Mind-reading devices are revealing the brain's secrets AI翻译
  作者：Naddaf, Miryam
  摘要：Implants and other technologies that decode neural activity can restore people's abilities to move and speak - and help researchers to understand how the brain works.