Nature

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• I peer into volcanoes to see when they'll blow AI翻译
  作者：Simons, Margaret
• Astrocyte cells in the brain have immune memory AI翻译
  作者：Sofroniew, Michael V.
  作者单位：University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA
  摘要：The central nervous system's astrocyte cells respond to injury and disease. The finding that they form molecular memories of certain responses, and that these modify inflammatory signalling, sheds light on autommunity.
• Ketamine is in the spotlight thanks to Elon Musk - but is it the right treatment for depression? AI翻译
  作者：Adam, David
  摘要：The entrepreneur endorses the drug, but researchers caution that it's not to be taken lightly.
• Controlling the helicity of light by electrical magnetization switching AI翻译
  作者：Dainone, Pambiang Abel; Prestes, Nicholas Figueiredo; Renucci, Pierre; Bouche, Alexandre; Morassi, Martina; Devaux, Xavier; Lindemann, Markus; George, Jean-Marie; Jaffres, Henri; Lemaitre, Aristide; Xu, Bo; Stoffel, Mathieu; Chen, Tongxin; Lombez, Laurent; Lagarde, Delphine; Cong, Guangwei; Ma, Tianyi; Pigeat, Philippe; Vergnat, Michel; Rinnert, Herve; Marie, Xavier; Han, Xiufeng; Mangin, Stephane; Rojas-Sanchez, Juan-Carlos; Wang, Jian-Ping; Beard, Matthew C.; Gerhardt, Nils C.; Zutic, Igor; Lu, Yuan
  作者单位：Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite de Lorraine; Universite Paris Saclay; Thales Group; Centre National de la Recherche Scientifique (CNRS); Universite Federale Toulouse Midi-Pyrenees (ComUE); Universite de Toulouse; Institut National des Sciences Appliquees de Toulouse; Centre National de la Recherche Scientifique (CNRS); Universite Toulouse III - Paul Sabatier; Institut Polytechnique de Paris; Ecole Polytechnique; Centre National de la Recherche Scientifique (CNRS); Universite Paris Saclay; Universite Paris Cite; Ruhr University Bochum; Chinese Academy of Sciences; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; National Institute of Advanced Industrial Science & Technology (AIST); Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Minnesota System; University of Minnesota Twin Cities; United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; State University of New York (SUNY) System; University at Buffalo, SUNY
  摘要：Controlling the intensity of emitted light and charge current is the basis of transferring and processing information1. By contrast, robust information storage and magnetic random-access memories are implemented using the spin of the carrier and the associated magnetization in ferromagnets2. The missing link between the respective disciplines of photonics, electronics and spintronics is to modulate the circular polarization of the emitted light, rather than its intensity, by electrically contr...
• Adding scientific signs to Indian Sign Language will create a more inclusive field for deaf students AI翻译
  作者：Padmanaban, Deepa; Madhusoodanan, Jyoti
  摘要：Digvijay Singh, a deaf sign-language educator, works with biology researchers and sign-language specialists to add to the scientific lexicon for deaf students in India.
• What Putin's next term means for science AI翻译
  作者：Dobrovidova, Olga
  摘要：Researchers in Russia expect growing isolation as Vladimir Putin embarks on six more years as president.
• The 50th anniversary of a key paper on how bird flight evolved AI翻译
  作者：Padian, Kevin
  作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley
  摘要：For a century, scientists pondered whether bird flight evolved by animals gliding down from trees or by creatures running and flapping from the ground up. A landmark 1974 paper reset the debate to focus on the evolution of the flight stroke instead.
• The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation AI翻译
  作者：Xu, Pengbiao; Liu, Ying; Liu, Chong; Guey, Baptiste; Li, Lingyun; Melenec, Pauline; Ricci, Jonathan; Ablasser, Andrea
  作者单位：Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Jiangnan University
  摘要：Cyclic GMP-AMP synthase (cGAS) senses aberrant DNA during infection, cancer and inflammatory disease, and initiates potent innate immune responses through the synthesis of 2 ' 3 '-cyclic GMP-AMP (cGAMP)1-7. The indiscriminate activity of cGAS towards DNA demands tight regulatory mechanisms that are necessary to maintain cell and tissue homeostasis under normal conditions. Inside the cell nucleus, anchoring to nucleosomes and competition with chromatin architectural proteins jointly prohibit cG...
• The hagfish genome and the evolution of vertebrates AI翻译
  作者：Marletaz, Ferdinand; Timoshevskaya, Nataliya; Timoshevskiy, Vladimir A.; Parey, Elise; Simakov, Oleg; Gavriouchkina, Daria; Suzuki, Masakazu; Kubokawa, Kaoru; Brenner, Sydney; Smith, Jeramiah J.; Rokhsar, Daniel S.
  作者单位：University of London; University College London; Okinawa Institute of Science & Technology Graduate University; University of Kentucky; University of Vienna; Shizuoka University; University of Tokyo; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Molecular & Cell Biology (IMCB); University of California System; University of California Berkeley; Chan Zuckerberg Initiative (CZI); University of London; University College London
  摘要：As the only surviving lineages of jawless fishes, hagfishes and lampreys provide a crucial window into early vertebrate evolution1-3. Here we investigate the complex history, timing and functional role of genome-wide duplications4-7 and programmed DNA elimination8,9 in vertebrates in the light of a chromosome-scale genome sequence for the brown hagfish Eptatretus atami. Combining evidence from syntenic and phylogenetic analyses, we establish a comprehensive picture of vertebrate genome evoluti...
• Five million years of Antarctic Circumpolar Current strength variability AI翻译
  作者：Lamy, Frank; Winckler, Gisela; Arz, Helge W.; Farmer, Jesse R.; Gottschalk, Julia; Lembke-Jene, Lester; Middleton, Jennifer L.; van der Does, Michelle; Tiedemann, Ralf; Alvarez Zarikian, Carlos; Basak, Chandranath; Brombacher, Anieke; Dumm, Levin; Esper, Oliver M.; Herbert, Lisa C.; Iwasaki, Shinya; Kreps, Gaston; Lawson, Vera J.; Lo, Li; Malinverno, Elisa; Martinez-Garcia, Alfredo; Michel, Elisabeth; Moretti, Simone; Moy, Christopher M.; Ravelo, Ana Christina; Riesselman, Christina R.; Saavedra-Pellitero, Mariem; Sadatzki, Henrik; Seo, Inah; Singh, Raj K.; Smith, Rebecca A.; Souza, Alexandre L.; Stoner, Joseph S.; Toyos, Maria; de Oliveira, Igor M. Venancio P.; Wan, Sui; Wu, Shuzhuang; Zhao, Xiangyu
  作者单位：Helmholtz Association; Alfred Wegener Institute, Helmholtz Centre for Polar & Marine Research; University of Bremen; Columbia University; Columbia University; Leibniz Institut fur Ostseeforschung Warnemunde; University of Massachusetts System; University of Massachusetts Boston; University of Kiel; Texas A&M University System; Texas A&M University College Station; University of Delaware; Yale University; State University of New York (SUNY) System; Stony Brook University; Japan Agency for Marine-Earth Science & Technology (JAMSTEC); Rutgers University System; Rutgers University New Brunswick; National Taiwan University; University of Milano-Bicocca; Max Planck Society; Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); CEA; University of Otago; University of California System; University of California Santa Cruz; University of Portsmouth; Korea Institute of Ocean Science & Technology (KIOST); Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Bhubaneswar; University of Massachusetts System; University of Massachusetts Amherst; Universidade Federal do Rio de Janeiro; Oregon State University; Universidade Federal Fluminense; Chinese Academy of Sciences; South China Sea Institute of Oceanology, CAS; University of Lausanne; Research Organization of Information & Systems (ROIS); National Institute of Polar Research (NIPR) - Japan
  摘要：The Antarctic Circumpolar Current (ACC) represents the world's largest ocean-current system and affects global ocean circulation, climate and Antarctic ice-sheet stability 1-3 . Today, ACC dynamics are controlled by atmospheric forcing, oceanic density gradients and eddy activity 4 . Whereas palaeoceanographic reconstructions exhibit regional heterogeneity in ACC position and strength over Pleistocene glacial-interglacial cycles 5-8 , the long-term evolution of the ACC is poorly known. Here we...