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作者:Brouillette, Monique
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作者:Ninh, V. K.; Calcagno, D. M.; Yu, J. D.; Zhang, B.; Taghdiri, N.; Sehgal, R.; Mesfin, J. M.; Chen, C. J.; Kalhor, K.; Toomu, A.; Duran, J. M.; Adler, E.; Hu, J.; Zhang, K.; Christman, K. L.; Fu, Z.; Bintu, B.; King, K. R.
作者单位:University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要:Sterile inflammation after myocardial infarction is classically credited to myeloid cells interacting with dead cell debris in the infarct zone1,2. Here we show that cardiomyocytes are the dominant initiators of a previously undescribed type I interferon response in the infarct borderzone. Using spatial transcriptomics analysis in mice and humans, we find that myocardial infarction induces colonies of interferon-induced cells (IFNICs) expressing interferon-stimulated genes decorating the borde...
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作者:Fernandez-Llamazares, Alvaro; Fa, Julia E.; Brockington, Dan; Brondizio, Eduardo S.; Carino, Joji; Corbera, Esteve; Ferrari, Maurizio Farhan; Kobei, Daniel; Malmer, Pernilla; Marquez, Guadalupe Yesenia H.; Molnar, Zsolt; Tugendhat, Helen; Garnett, Stephen T.
作者单位:Autonomous University of Barcelona; Autonomous University of Barcelona; Manchester Metropolitan University; CGIAR; Center for International Forestry Research (CIFOR); ICREA; Indiana University System; Indiana University Bloomington; Universidade Estadual de Campinas; Stockholm University; HUN-REN; HUN-REN Centre for Ecological Research; Charles Darwin University
摘要:A much-cited statistic about how much of the world's biodiversity is under Indigenous stewardship is unsupported - and could harm the cause it is meant to support. Credit: Joan de la MallaA man and small child sit together weaving palms in the Bolivian Amazon
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作者:Hedley, Esme
摘要:Climate scientist Carly McLachlan partners with the UK band to put the environmental impact of concerts centre stage.
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作者:Padmanaban, Veena; Keller, Isabel; Seltzer, Ethan S.; Ostendorf, Benjamin N.; Kerner, Zachary; Tavazoie, Sohail F.
作者单位:Rockefeller University; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Humboldt University of Berlin; Free University of Berlin; Charite Universitatsmedizin Berlin; Berlin Institute of Health; Helmholtz Association; Max Delbruck Center for Molecular Medicine; Rockefeller University
摘要:Tumour innervation is associated with worse patient outcomes in multiple cancers(1,2), which suggests that it may regulate metastasis. Here we observed that highly metastatic mouse mammary tumours acquired more innervation than did less-metastatic tumours. This enhanced innervation was driven by expression of the axon-guidance molecule SLIT2 in tumour vasculature. Breast cancer cells induced spontaneous calcium activity in sensory neurons and elicited release of the neuropeptide substance P (S...
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作者:[Anonymous]
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作者:Hedley, Esme; Seiser, Bernd
作者单位:Austrian Academy of Sciences
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作者:Sonne, Christian
作者单位:Aarhus University
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作者:Zhang, Chuankun; Ooi, Tian; Higgins, Jacob S.; Doyle, Jack F.; von der Wense, Lars; Beeks, Kjeld; Leitner, Adrian; Kazakov, Georgy A.; Li, Peng; Thirol, Peter G.; Schumm, Thorsten; Ye, Jun
作者单位:University of Colorado System; University of Colorado Boulder; National Institute of Standards & Technology (NIST) - USA; University of Colorado System; University of Colorado Boulder; Technische Universitat Wien; University of Munich; Johannes Gutenberg University of Mainz; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要:Optical atomic clocks(1,2) use electronic energy levels to precisely keep track of time. A clock based on nuclear energy levels promises a next-generation platform for precision metrology and fundamental physics studies. Thorium-229 nuclei exhibit a uniquely low-energy nuclear transition within reach of state-of-the-art vacuum ultraviolet (VUV) laser light sources and have, therefore, been proposed for construction of a nuclear clock(3,4). However, quantum-state-resolved spectroscopy of the Th...
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作者:Chebii, Vivien
作者单位:University of Witwatersrand