作者：Sng, Xavier Y. X.; Voigt, Valentina; Schuster, Iona S.; Fleming, Peter; Deuss, Felix A.; Abuwarwar, Mohammed H.; van Dommelen, Serani L. H.; Neate, Georgia E. G.; Arnold, Riley M.; Horsnell, Harry L.; Daly, Sheridan; Golzarroshan, Bagher; Varelias, Antiopi; Lyman, Stewart D.; Scalzo, Anthony A.; Hill, Geoffrey R.; Mueller, Scott N.; Wikstrom, Matthew E.; Berry, Richard; Rossjohn, Jamie; Fletcher, Anne L.; Andoniou, Christopher E.; Degli-Esposti, Mariapia A.
作者单位：Monash University; Monash University; Lions Eye Institute; University of Western Australia; Monash University; Monash University; University of Melbourne; Peter Doherty Institute; QIMR Berghofer Medical Research Institute; Fred Hutchinson Cancer Center; University of Washington; University of Washington Seattle; Cardiff University
摘要：The movement of dendritic cells and T cells within secondary lymphoid organs is critical for the development of adaptive immune responses1,2. Central to this process is the fibroblastic reticular cell (FRC) network, which forms a highly organized conduit system that facilitates the movement of and interactions between dendritic cells and T cells3, 4, 5-6. Previous studies have partly characterized how FRCs support these interactions7,8. However, the molecular mechanisms that operate under phys...
作者：Wolff, Eric W.
摘要：Antarctic ice cores hint that changes in the ocean might have played a larger part than have greenhouse gases in key climate shifts of the past three million years.
作者：Ganesh, Lakshmanan; Burstein, Ezra; Guha-Niyogi, Anuradha; Louder, Mark K.; Mascola, John R.; Klomp, Leo W. J.; Wijmenga, Cisca; Duckett, Colin S.; Nabel, Gary J.
作者：Gaudi, Andrea U.; Meier, Michelle; Baltaci, Oguzhan F.; Chowdhary, Sayali; Tulenko, Frank J.; Dudczig, Stefanie; Stamatis, Sebastian-Alexander; Paterson, Scott; Yu, Hujun; Galeano, Maria Cristina Rondon; Mason, Elizabeth; Miles, Lee B.; Bryson-Richardson, Robert J.; Pask, Andrew J.; Vukovic, Jana; Lagendijk, Anne K.; Smith, Kelly A.; Kaslin, Jan; Harrison, Michael Rm; Currie, Peter D.; Bower, Neil I.; Hogan, Benjamin M.
作者单位：Peter Maccallum Cancer Center; Peter Maccallum Cancer Center; University of Melbourne; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Australian Regenerative Medicine Institute; Monash University; European Molecular Biology Laboratory (EMBL); Monash University; EMBL Australia; Monash University; University of Melbourne; University of Queensland; University of Queensland; University of Queensland; University of Melbourne
摘要：The vertebrate central nervous system is protected by the blood-brain barrier and meningeal membranes, which ensure immune privilege1. In the mammalian brain, microglia and barrier-associated or border-associated macrophages (BAMs) provide immune surveillance and scavenge wastes2, yet how evolution shaped immune-cell diversity and function is not understood. In zebrafish, a vascular-derived mural lymphatic endothelial cell (muLEC) lineage fulfils scavenger cell functions at central nervous sys...
