44期

最新文章

• Hierarchical assembly of biomass fiber-lamella-macromolecule networks for biocomposites with high strength and water-resistant sealing AI翻译
  作者：Qiu, Yijin; Zhang, Dachuan; Zhou, Zhixuan; Yang, Di; Qian, Chen; Chen, Chaoji; Zhao, Ze; Deng, Hongbing
  作者单位：Wuhan University; National University of Singapore; Wuhan University
  摘要：Enhancing mechanical strength and water resistance in cellulose fiber-based materials is crucial for their adoption as sustainable alternatives to petroleum plastics. However, achieving these improvements through a simple, economical, and ecofriendly approach remains a major challenge. Here, we present a chitosan (CS)-driven multiscale assembly and rearrangement strategy that produces fiber-lamella biocomposites with outstanding mechanical strength and water resistance, achieved without any ch...
• Regional postdeforestation weathering feedback drove diachronous C-S cycle perturbations during the end-Permian crisis AI翻译
  作者：Chen, Jianbo; Lu, Binjian; Du, Longye; Lin, Mang; Shen, Shu-Zhong; Montanez, Isabel P.; Feng, Zhuo
  作者单位：Yunnan University; Chinese Academy of Sciences; Guangzhou Institute of Geochemistry, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Nanjing University; Nanjing University; University of California System; University of California Davis
  摘要：The Permian-Triassic (P-Tr) transition (similar to 252 Ma) witnessed Earth's most severe biocrisis, which has long been linked to Siberian Traps volcanism and associated environmental upheaval. Major perturbation of the global carbon (C) and sulfur (S) cycles is mainly inferred from marine delta C-13 and delta S-34 records, whereas few existing terrestrial records link delta S-34 fluctuations to widespread dispersal and fallout of volcanogenic sulfate aerosols. Mounting evidence, however, reve...
• Mineralized sclerites in the gorgonian coral Leptogorgia chilensis as a natural jamming system AI翻译
  作者：Hu, Chenhao; Tutika, Ravi; Deng, Zhifei; Jia, Zian; Chen, Liuni; Chen, Hongshun; Geng, Yang; Xiao, Xianghui; Shevchenko, Pavel D.; Pierre, Christoph; Weaver, James C.; Baum, Daniel; Bartlett, Michael D.; Li, Ling
  作者单位：University of Pennsylvania; Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University; United States Department of Energy (DOE); Brookhaven National Laboratory; United States Department of Energy (DOE); Argonne National Laboratory; University of California System; University of California Santa Barbara; Harvard University; Massachusetts Institute of Technology (MIT); Zuse Institute Berlin
  摘要：The soft corals (Cnidaria, Octocorallia), a diverse group of colonial marine invertebrates, can reversibly tune their body stiffness in response to external stimuli. This capability is attributed to their dynamic skeletal systems, which consist of thousands of mineralized skeletal elements, called sclerites, embedded within a gel-like matrix that swells/deswells and unjams/jams the sclerites, thus modulating skeletal stiffness. While sclerite morphology is widely used for species identificatio...
• Global impact of anthropogenic NH3 emissions on upper tropospheric aerosol formation AI翻译
  作者：Xenofontos, Christos; Kohl, Matthias; Ruhl, Samuel; Almeida, Joao; Caudillo-Plath, Lucia; Cruz-Simbron, Romulo; Dada, Lubna; Duplissy, Jonathan; Ehrhart, Sebastian; Finkenzeller, Henning; Hoehler, Kristina; Kong, Weimeng; Kunkler, Felix; Lietzke, Clara J.; Mentler, Bernhard; Morawiec, Aleksandra; Onnela, Antti; Rato, Pedro; Rorup, Birte; Russell, Douglas M.; Schervish, Meredith; Scholz, Wiebke; Sebastian, Milin Kaniyodical; Simon, Mario; Sommer, Eva; Tong, Yandong; Umo, Nsikanabasi Silas; Unfer, Gabriela R.; Vettikkat, Lejish; Yang, Boxing; Yu, Wenjuan; Zgheib, Imad; Zheng, Zhensen; Curtius, Joachim; Donahue, Neil M.; Flagan, Richard C.; Gordon, Hamish; El Haddad, Imad; Hansel, Armin; Harder, Hartwig; He, Xu-Cheng; Kirkby, Jasper; Kulmala, Markku; Lehtipalo, Katrianne; Moehler, Ottmar; Petaja, Tuukka; Poehlker, Mira L.; Schobesberger, Siegfried; Stolzenburg, Dominik; Wang, Mingyi; Winkler, Paul M.; Worsnop, Douglas R.; Hoepfner, Michael; Volkamer, Rainer; Pozzer, Andrea; Lelieveld, Jos; Christoudias, Theodoros
  作者单位：Max Planck Society; European Organization for Nuclear Research (CERN); Goethe University Frankfurt; University of Colorado System; University of Colorado Boulder; Swiss Federal Institutes of Technology Domain; Paul Scherrer Institute; University of Helsinki; Helmholtz Association; Karlsruhe Institute of Technology; California Institute of Technology; University of Innsbruck; University of Vienna; University of California System; University of California Irvine; Leibniz Association; Leibniz Institut fur Tropospharenforschung (TROPOS); University of Eastern Finland; TOFWERK AG; Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University; University of Cambridge; Nanjing University; Beijing University of Chemical Technology; Finnish Meteorological Institute; Technische Universitat Wien; University of Chicago; Aerodyne Research; Helmholtz Association; Karlsruhe Institute of Technology
  摘要：Anthropogenic ammonia (NH3) emissions have significantly increased in recent decades due to enhanced agricultural activities, contributing to global air pollution. While the effects of NH3 on surface air quality are well documented, its influence on particle dynamics in the upper troposphere-lower stratosphere (UTLS) and related aerosol impacts remain unquantified. NH3 reaches the UTLS through convective transport and can enhance new particle formation (NPF). This modeling study evaluates the ...
• p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer AI翻译
  作者：Aylon, Yael; Furth, Noa; Pirona, Anna C.; Lavie, Adi; Fedorova, Olga; Hassin, Ori; Padrao, Nuno; Steinmetz, Maxime; Sarusi-Potuguez, Avital; Fellus-Alyagor, Liat; Shimoni, Irit; Dassa, Bareket; Zwart, Wilbert; Shema, Efrat; Oren, Moshe
  作者单位：Weizmann Institute of Science; Weizmann Institute of Science; Weizmann Institute of Science; Netherlands Cancer Institute; Weizmann Institute of Science; Weizmann Institute of Science; Weizmann Institute of Science
  摘要：Breast cancer is the leading cause of death in women under 50. The majority of breast cancers are estrogen receptor alpha- positive (ER+) and are commonly treated with hormonal therapies such as tamoxifen that inhibit ER activity. The TP53 tumor suppressor gene, encoding the p53 protein, is the most frequently mutated gene in breast cancer, and TP53 mutations are associated with diminished tamoxifen response and worse prognosis for breast cancer patients. Here, we report that in breast cancer ...
• Divergent patterns of engagement with partisan and low- quality news across seven social media platforms AI翻译
  作者：Mosleh, Mohsen; Allen, Jennifer; Rand, David G.
  作者单位：University of Oxford; Massachusetts Institute of Technology (MIT); New York University; Cornell University; Cornell University; Cornell University
  摘要：In recent years, social media has become increasingly fragmented, as platforms evolve and new alternatives emerge. Yet most research studies a single platform-typically X/ Twitter, or occasionally Facebook-leaving little known about the broader social media landscape. Here, we shed light on patterns of cross- platform variation in the high- stakes context of news sharing. We examine the relationship between user engagement and news domains' political orientation and quality across seven platfo...
• Learning expectations shape cognitive control allocation AI翻译
  作者：Obando, Javier Alejandro Masis; Musslick, Sebastian; Cohen, Jonathan D.
  作者单位：Princeton University; University Osnabruck; Brown University; Princeton University
  摘要：Current models frame the allocation of cognitive control as a process of expected utility maximization. The benefits of a candidate control signal are weighed against its costs counterintuitive behavior of longer deliberation, which is less rewarding in the short term, it is nevertheless normative to account for the value of learning when determining control allocation. Here, we sought to test this proposal by examining whether people were willing to allocate greater control and thereby expend...
• FibrilPaint to determine the length of Tau amyloids in fluids AI翻译
  作者：Pedrola, Julia Aragones; Dekker, Francoise A.; Garfagnini, Tommaso; Mayer, Guy; Koopman, Margreet B.; Bergmeijer, Menno; Heesink, Gobert; Rots, Iris; Claessens, Mireille M. A. E.; Forster, Friedrich; Hoozemans, Jeroen J. M.; Jensen, Henrik; Friedler, Assaf; Rudiger, Stefan G. D.
  作者单位：University of York - UK; Utrecht University; Utrecht University; Utrecht University; Hebrew University of Jerusalem; Utrecht University; University of Twente; University of Amsterdam; Vrije Universiteit Amsterdam
  摘要：Tau aggregation into amyloid fibrils is linked to the development of neurodegenerative diseases, including Alzheimer's disease (AD). The molecular processes driving aggregation in disease are still being uncovered, highlighting the need for innovative tools to study aggregation reactions. Here, we introduce FibrilPaint1 as a tool to measure the size of Tau amyloid fibrils in fluids, from early aggregation stages to mature fibrils. FibrilPaint1 is a 22mer peptide with exciting properties: i) Fi...
• Confronting the inevitable: Harnessing technology to contain systemic scientific fraud AI翻译
  作者：Singer, Philipp
  作者单位：Roche Holding
• A cell- based scrambling assay reveals the phospholipid headgroup preference of TMEM16F on the plasma membrane AI翻译
  作者：Teo, Chin Fen; Tuomivaara, Sami T.; van Hilten, Niek; Crottes, David; Jan, Yuh Nung; Grabe, Michael; Jan, Lily Y.
  作者单位：University of Helsinki; Universite de Tours; Institut National de la Sante et de la Recherche Medicale (Inserm); University of California System; Howard Hughes Medical Institute; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco
  摘要：The asymmetric resting distribution of the three major phospholipid classes on the mammalian plasma membrane, with phosphatidylserine and phosphatidylethanolamine mostly on the inner leaflet and phosphatidylcholine mostly on the outer leaflet, is maintained by ATP-dependent flippases and floppases that exhibit headgroup selectivity. Upon signaling cues, this asymmetry can be dissipated by various phospholipid scramblases, allowing cells to respond to stimuli and adapt to different physiologica...