6786期

最新文章

• Imagining the rich lives of invertebrates AI翻译
  作者：King, Barbara J.
• Endangered Species Act changes threaten reefs AI翻译
  作者：Anthony, Colin J.; Lock, Colin; Johnson, Steven Manaoakamai; Maruyama, Shinichiro; Raymundo, Laurie J.
  作者单位：University of Guam; University of Tokyo; University of Technology Sydney; Cornell University
• Building a better working dog AI翻译
  作者：Grimm, David
• e-Waste trade drives environmental injustice AI翻译
  作者：Peng, Lizeng; Jin, Chuan
  作者单位：Shandong Academy of Agricultural Sciences; Hainan University
• Fishing ban halts seven decades of biodiversity decline in the Yangtze River AI翻译
  作者：Xiong, Fangyuan; Li, Zhongyang; Brosse, Sebastien; Olden, Julian D.; Cooke, Steven J.; Yang, Bo; Lu, Ying; Gao, Wenqi; Xin, Wei; Chen, Yushun
  作者单位：Chinese Academy of Sciences; Institute of Hydrobiology, CAS; Chinese Academy of Sciences; Institute of Hydrobiology, CAS; Hunan University of Science & Technology; Hunan University of Science & Technology; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Institut de Recherche pour le Developpement (IRD); Centre National de la Recherche Scientifique (CNRS); Communaute d'universites et etablissements de Toulouse (Comue); Universite de Toulouse (EPE); Institut National Polytechnique de Toulouse; University of Washington; University of Washington Seattle; Carleton University; Hainan University
  摘要：China's rapid economic development has triggered an unparalleled freshwater biodiversity crisis since the 1950s. To restore fisheries resources, the Yangtze River Fishing Ban was implemented in 2021 to cease all basin-wide commercial fishing. We evaluate the effectiveness of this large-scale conservation action by assessing fish communities across mainstem habitats before and after the ban (2018 to 2023). The seven-decadal biodiversity loss was halted with improvements in fish biomass, body co...
• Myelin sheaths in the central nervous system can withstand damage and dynamically remodel AI翻译
  作者：Arafa, Donia; van de Korput, Julia; Braaker, Philipp N.; Higgins, Kieran P.; Meijns, Niels R. C.; Marshall-Phelps, Katy L. H.; Meng, Julia; Soong, Daniel; Scalia, Eleonora; Lathem, Kyle; Keatinge, Marcus; Richmond, Claire; Klingseisen, Anna; Main, Marja; Neely, Sarah A.; Hampton, David W.; Duncan, Greg J.; Schenk, Geert J.; Groot, Marie Louise; Chandran, Siddharthan; Emery, Ben; Luchicchi, Antonio; Kole, Maarten H. P.; Williams, Anna C.; Lyons, David A.
  作者单位：University of Edinburgh; University of Edinburgh; University of Edinburgh; Royal Netherlands Academy of Arts & Sciences; Netherlands Institute for Neuroscience (NIN-KNAW); Utrecht University; University of Amsterdam; Vrije Universiteit Amsterdam; University of Amsterdam; University of Edinburgh; University of Edinburgh; Oregon Health & Science University; Vrije Universiteit Amsterdam; Trinity College Dublin; Royal Netherlands Academy of Arts & Sciences; Netherlands Institute for Neuroscience (NIN-KNAW); University of Minnesota System; University of Minnesota Twin Cities
  摘要：Myelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models is characterized by myelin swelling. We show, through live imaging, that myelin swelling does not always lead to myelin loss and that swellings can sometimes resolve, allowing sheaths to remodel. Increased neuronal activity during early demyelination exacerbates myelin damage, whereas reducing neu...
• Genomic approaches to accelerate American chestnut restoration AI翻译
  作者：Westbrook, Jared W.; Malukiewicz, Joanna; Zhang, Qian; Sreedasyam, Avinash; Jenkins, Jerry W.; Lakoba, Vasiliy; Fitzsimmons, Sara; Van Clief, Jamie; Collins, Kendra; Hoy, Stephen; Stark, Cassie; Graboski, Lake; Jenkins, Eric; Saielli, Thomas M.; Jarrett, Benjamin T.; Wigfield, Lucinda J.; Kerwien, Lauren M.; Wilbur, Ciera; Sandercock, Alexander M.; Craddock, J. Hill; Kerio, Susanna; Zhebentyayeva, Tetyana; Fan, Shenghua; Thomas, Austin M.; Abbott, Albert G.; Nelson, C. Dana; Xia, Xiaoxia; Mckenna, James R.; Kell, Caleb; Williams, Melissa; Boston, Loribeth; Plott, Christopher; Carle, Florian; Swatt, Jack; Ostroff, Jack; Jeffers, Steven N.; Mckeever, Kathleen; Smith, Erica; Ellis, Thomas J.; James, Joseph B.; Sisco, Paul; Newhouse, Andrew; Carlson, Erik; Powell, William A.; Hebard, Frederick V.; Scrivani, John; Heverly, Caragh; Cipollini, Martin; Clark, Brian; Evans, Eric; Levine, Bruce; Carlson, John E.; Goodstein, David; Orebaugh, Jack; Yang, Zamin K.; Martin, Madhavi Z.; Tannous, Joanna; Rush, Tomas A.; Engle, Nancy L.; Tschaplinski, Timothy J.; Grimwood, Jane; Schmutz, Jeremy; Holliday, Jason A.; Lovell, John T.
  作者单位：Virginia Polytechnic Institute & State University; University of Hamburg; HudsonAlpha Institute for Biotechnology; United States Department of Energy (DOE); University of Tennessee System; University of Tennessee at Chattanooga; Connecticut Agricultural Experiment Station; United States Department of Agriculture (USDA); United States Forest Service; United States Department of Agriculture (USDA); United States Forest Service; Clemson University; Purdue University System; Purdue University; Yale University; Austrian Academy of Sciences; Vienna Biocenter (VBC); Gregor Mendel Institute of Molecular Plant Biology (GMI); State University of New York (SUNY) System; State University of New York (SUNY) College of Environmental Science & Forestry; University System of Maryland; University of Maryland College Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; United States Department of Energy (DOE); Oak Ridge National Laboratory; State University System of Florida; University of Florida
  摘要：More than a century after two introduced pathogens killed billions of American chestnut trees, introgression of resistance alleles from Chinese chestnuts has contributed to the recovery of self-sustaining populations. However, progress has been slow because of the complex genetic architecture of resistance. To better understand blight resistance, we compared reference genomes, gene expression responses, and stem metabolite profiles of the resistant Chinese and susceptible American chestnut spe...
• Structural ontogeny of protein-protein interactions AI翻译
  作者：Yang, Aerin; Jiang, Hanlun; Jude, Kevin M.; Akpinaroglu, Deniz; Allenspach, Stephan; Li, Alex Jie; Bowden, James; Perez, Carla Patricia; Liu, Liu; Huang, Po-Ssu; Kortemme, Tanja; Listgarten, Jennifer; Garcia, K. Christopher
  作者单位：Stanford Medicine; Stanford University; University of California System; University of California Berkeley; Stanford Medicine; Stanford University; Howard Hughes Medical Institute; University of California System; University of California San Francisco; University of California System; University of California San Francisco; Stanford University; Stanford University; University of California System; University of California San Francisco; University of California System; University of California Berkeley
  摘要：Understanding how protein binding sites evolve interactions with other proteins could hold clues to targeting undruggable surfaces. We used synthetic coevolution to engineer new interactions between na & iuml;ve surfaces, simulating the de novo formation of protein complexes. We isolated seven distinct structural families of protein Z-domain complexes and found that synthetic complexes explore multiple shallow energy wells through ratchet-like docking modes, whereas complexes formed by natural...
• The elusive nature of consciousness AI翻译
  作者：Block, Ned
  作者单位：New York University
• Dihydroxyhexanoic acid biosynthesis controls turgor in pathogenic fungi AI翻译
  作者：Kumakura, Naoyoshi; Motoyama, Takayuki; Miyazawa, Keisuke; Nogawa, Toshihiko; Pernier, Julien; Yonehara, Katsuma; Sato, Mayuko; Goto, Yumi; Sakai, Kaori; Ishihama, Nobuaki; Matsumori, Kaisei; Gan, Pamela; Toyooka, Kiminori; Leveque-Fort, Sandrine; Koshino, Hiroyuki; Fukuma, Takeshi; O'Connell, Richard J.; Shirasu, Ken
  作者单位：RIKEN; Kanazawa University; Kanazawa University; Universite Paris Saclay; INRAE; University of Tokyo; Centre National de la Recherche Scientifique (CNRS); Universite Paris Saclay
  摘要：Many plant pathogenic fungi penetrate host surfaces mechanically, using turgor pressure generated by specialized infection cells called appressoria. These appressoria develop semipermeable cell walls and accumulate osmolytes internally to create turgor by osmosis. Although melanin is known to be important for turgor generation, the mechanism underlying wall semipermeability remains unclear. By using reverse genetics, we identified that the enzymes PKS2 and PBG13 are required for forming the se...