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作者：Dong, Subo; Wu, Zexuan; Ryu, Yoon-Hyun; Udalski, Andrzej; Mroz, Przemek; Rybicki, Krzysztof A.; Hodgkin, Simon T.; Wyrzykowski, Lukasz; Eyer, Laurent; Bensby, Thomas; Chen, Ping; Wang, Sharon X.; Gould, Andrew; Yang, Hongjing; Albrow, Michael D.; Chung, Sun-Ju; Han, Cheongho; Hwang, Kyu-Ha; Jung, Youn Kil; Shin, In-Gu; Shvartzvald, Yossi; Yee, Jennifer C.; Zang, Weicheng; Kim, Dong-Jin; Lee, Chung-Uk; Park, Byeong-Gon; Poleski, Radoslaw; Skowron, Jan; Szymanski, Michal K.; Soszynski, Igor; Pietrukowicz, Pawel; Kozlowski, Szymon; Skowron, Dorota M.; Ulaczyk, Krzysztof; Gromadzki, Mariusz; Ratajczak, Milena; Iwanek, Patryk; Wrona, Marcin; Mroz, Mateusz J.; Rixon, Guy; Harrison, Diana L.; Breedt, Elme
作者单位：Peking University; Peking University; Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; National Astronomical Observatory, CAS; Korea Astronomy & Space Science Institute (KASI); University of Warsaw; Weizmann Institute of Science; University of Cambridge; University of Geneva; Lund University; Zhejiang University; Zhejiang University; Tsinghua University; Max Planck Society; University System of Ohio; Ohio State University; Westlake University; University of Canterbury; Chungbuk National University; Smithsonian Institution; University of Warwick; Villanova University; University of Cambridge
摘要：A population of free-floating planets is known from gravitational microlensing surveys. None have a directly measured mass, owing to a degeneracy with the distance, but the population statistics indicate that many are less massive than Jupiter. We report a microlensing event-KMT-2024-BLG-0792/OGLE-2024-BLG-0516, which was observed from both ground- and space-based telescopes-that breaks the mass-distance degeneracy. The event was caused by an object with 0.219-0.046+0.075 Jupiter masses that i...
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作者：Fei, Chengbin; Zhang, Yadong; Wang, Mengru; Yang, Yuqian; Shi, Xiaoqiang; Wang, Shaojie; Guo, Huanxin; Guo, Chuanhang; Liu, He; Li, Mingze; Gu, Hangyu; Barlow, Stephen; You, Wei; Wang, Mengen; Marder, Seth R.; Huang, Jinsong
作者单位：University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of Colorado System; University of Colorado Boulder; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder
摘要：Phosphonic acid (PA)-based interlayers used in metal-halide perovskite solar cells (PSCs) can suffer from instability at elevated temperatures. We report that the acidic protons of PAs weakly bound to indium tin oxide (ITO) can accelerate the oxidation of iodide, decomposition of formamidinium, and reduction of lead ions and that these reactions accelerate at high temperature and on exposure to ultraviolet light. Also, some common PA molecules weakly bonded to ITO can desorb and react with per...
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作者：Jin, Qihan; Wang, Yukai; Chen, Dachuan; Liao, Jinyang; Cui, Zhanyuan; Fan, Yuxuan; Zeng, Anping; Xie, Mingqi; Cao, Longxing
作者单位：Fudan University; Westlake University; Westlake University; Westlake Laboratory; Westlake University; Westlake University; Westlake University; Westlake University; Westlake University; Westlake University; Westlake Laboratory
摘要：Small molecule-regulated protein oligomerization provides a powerful mechanism for manipulating biological processes by controlling protein proximity with high temporal precision. However, such systems only rarely exist in nature and remain a substantial challenge for de novo design. In this work, we describe a computational method for designing protein homooligomers whose assembly is regulated by small-molecule ligands with matching symmetry. We designed protein homotrimers regulated by the F...
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作者：Price, Michael
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作者：Han, Lijie; Li, Min; Li, Chuang; Zhao, Bosi; Wang, Zhongyi; Liu, Ye; Liu, Zhihan; Huang, Yafei; Liu, Liu; Geng, Haoran; He, Yuting; Guo, Jingyu; Wang, Shaoyun; Wang, Liming; Gu, Chaoheng; Shen, Junjun; Li, Zheng; Zhao, Jianyu; Zhou, Zhaoyang; Zhang, Xiaolan
作者单位：China Agricultural University; Northwest A&F University - China
摘要：Sex determination underpins genesis of male and female flowers with particularly important implications in plant breeding. Auxin and ethylene regulate femaleness in cucurbits. In this work, we identified an auxin response factor 3 (CsARF3) that plays an essential role in carpel development in cucumber. Deletion of CsARF3 resulted in an androecious phenotype with only male flowers, whereas overexpression of CsARF3 led to an increased number of female flowers. CsARF3 promotes femaleness by direc...
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作者：Kaiser, Jocelyn
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作者：Swarr, Amanda Lock
作者单位：University of Washington; University of Washington Seattle
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作者：Thompson, Mackenzie J.; Tessier, Christian J. G.; Ananchenko, Anna; Henault, Camille; Emlaw, Johnathon R.; Dehez, Francois; Zarkadas, Eleftherios; dacosta, Corrie J. B.; Nury, Hugues; Baenziger, John E.
作者单位：University of Ottawa; University of Ottawa; Centre National de la Recherche Scientifique (CNRS); Universite de Lorraine; European Molecular Biology Laboratory (EMBL); CEA; Communaute Universite Grenoble Alpes; Centre National de la Recherche Scientifique (CNRS); Universite Grenoble Alpes (UGA); CEA; Centre National de la Recherche Scientifique (CNRS); Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); University of California System; University of California Berkeley; Carleton University; Rockefeller University
摘要：Communication at synapses is facilitated by postsynaptic receptors, which convert a chemical signal into an electrical response. For ligand-gated ion channels, agonist binding triggers rapid transitions through intermediate states leading to a transient open-pore conformation, with these transitions shaping the postsynaptic response. In this work, we determine structures of the muscle-type nicotinic acetylcholine receptor in unliganded, mono-liganded, and di-liganded states. Agonist binding to...
