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作者:Deak, Peter
作者单位:Drexel University
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作者:Jin, Wenxing; Yu, Cong; Zhang, Yan; Cao, Changchang; Xia, Tianfan; Song, Ge; Cai, Zhaokui; Xue, Yuanchao; Zhu, Bing; Xu, Rui-Ming
作者单位:Chinese Academy of Sciences; Institute of Biophysics, CAS; Nanjing Institute of Geology & Paleontology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Institute of Biophysics, CAS; Nanjing Institute of Geology & Paleontology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
摘要:Long interspersed nuclear element-1 (LINE-1 or L1), the only autonomously active retrotransposon in humans today, constitutes a large proportion of the genome and continues to evolve the genome and impact fundamental biological processes. L1 retrotransposition critically depends on its endonuclease and reverse transcriptase subunit open reading frame 2 protein (ORF2p), which targets genomic loci and nicks DNA using an evolutionarily distinct yet not fully understood mechanism. Our structural a...
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作者:Normile, Dennis
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作者:Offord, Catherine
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作者:Tang, Bijun; Lu, Jing; Leontovycova, Hana; Hoffmann, Gesa; Rowe, James H.; O'Donnell, Sacha Fouquay; Grange-Guermente, Mathieu; Larsen, Bo; Wimalasekera, Rinukshi; Carella, Philip; Incarbone, Marco; Kalachova, Tetiana; Jones, Alexander M.
作者单位:University of Cambridge; Czech Academy of Sciences; Institute of Experimental Botany of the Czech Academy of Sciences; Max Planck Society; University of Sheffield; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); John Innes Centre
摘要:Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled by plants but can be suppressed by pathogens to overcome immunity. Understanding SA dynamics at high spatiotemporal resolution remains challenging owing to limitations in existing detection methods that are indirect, destructive, or lacking in cellular precision and temporal resolution. We develo...
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作者:Aguilar, Liz A.; Miller-Crews, Isaac; Dobris, Jeremy M.; Tracy, Jo Anne; Macklin, Paul; Dixit, Shantanu; Jacobson, Ryan A.; Evans, Rachel L.; McGuire, Evan L.; Beverly, Daniel P.; Reichard, Dustin G.; Rosvall, Kimberly A.
作者单位:Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington; University System of Ohio; Ohio Wesleyan University
摘要:On 8 April 2024, a total solar eclipse disrupted light-dark cycles for North American birds during the lead-up to spring reproduction. Compiling more than 10,000 community observations and artificial intelligence analyses of nearly 100,000 vocalizations, we found that bird behavior was substantially affected by these few minutes of unexpected afternoon darkness. More than half of wild bird species changed their biological rhythms, with many producing a dawn chorus in the aftermath of the eclip...
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作者:Cabico, Gaea
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作者:Cho, Adrian
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作者:Glynn, Audrey R.
作者单位:University of California System; University of California Berkeley
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作者:He, Zhiren; Khalsa, Guru
作者单位:University of North Texas System; University of North Texas Denton