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作者：Bonafina, Antonela; Nguyen, Laurent
作者单位：University of Liege
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作者：Price, Michael H. H.; Berchtold, Adrienne
作者单位：Simon Fraser University
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作者：Farke, Andrew A.
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作者：Schuttelkopf, Philipp; Tajik, Mohammadamin; Bazhan, Nataliia; Cataldini, Federica; Ji, Si-Cong; Schmiedmayer, Jorg; Moller, Frederik
作者单位：Technische Universitat Wien; California Institute of Technology; Max Planck Society
摘要：Transport properties define materials as insulators, metals, or superconductors. A fundamental parameter is the Drude weight, which quantifies the ballistic transport of charge carriers. In this study, we measured the Drude weights of an ultracold gas of interacting bosonic atoms confined to one dimension, characterizing atomic and energy currents induced by applying a constant force and by joining two subsystems prepared in different equilibrium states. We demonstrate dissipationless transpor...
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作者：Pinto, Maria
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作者：Wei, Eric Q.; Beyer, Martin; Brown, Kemar J.; Bansbach, Alexander J.; Gorham, Joshua M.; Mcdonough, Barbara; Chen, Huachen; Khoramjoo, Mobin; Zhang, Anran; Bishop, Brian; Ahmad, Ferhaan; Del Rio, Carlos; Chang, Ching-Pin; Ryba, David M.; Day, Sharlene M.; Fatkin, Diane; Oudit, Gavin Y.; Seidman, Christine E.; Seidman, Jonathan G.
作者单位：Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; German Centre for Cardiovascular Research; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; University of Alberta; University of Iowa; Bristol-Myers Squibb; University of Pennsylvania; Victor Chang Cardiac Research Institute; University of New South Wales Sydney; NSW Health; St Vincents Hospital Sydney
摘要：Hypertrophic cardiomyopathy (HCM), a genetic heart disease defined by unexplained cardiac wall thickening, is a leading cause of sudden death worldwide. However, the three-dimensional organization of cardiac tissue underlying left ventricular hypertrophy remains poorly understood. We developed CaMVIA-3D, a deep-learning volumetric imaging and analysis pipeline to characterize cardiac microarchitecture. Analysis of tissues from HCM hearts revealed genotype-specific differences in cardiomyocyte ...
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作者：Clery, Daniel
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作者：Deng, Jieru; Yan, Yuting; Zhang, Xiaoyue; Walsh, Calum J.; Montassier, Emmanuel; Sinha, Debajyoti; Wang, Huimeng; Mousavizadeh, Atieh; Ashayeripanah, Mitra; Mak, Jeffrey Y. W.; Koay, Hui-Fern; Poch, Tobias; Alexandre, Yannick O.; Mueller, Scott N.; Vasanthakumar, Ajithkumar; Stinear, Tim P.; Jameson, Vanta J.; Perez-Gonzalez, Alexis; Kingham, Jenny; Phan, Tri Giang; Potemkin, Nikita; Dryburgh, Lachlan; Schroeder, Jan; Fairlie, David P.; Mackay, Laura K.; Chen, Zhenjun; Cook, Laura; Hachani, Abderrahman; Corbett, Alexandra J.; Roquilly, Antoine; Villadangos, Jose A.; McWilliam, Hamish E. G.
作者单位：University of Melbourne; Peter Doherty Institute; Tsinghua University; Sichuan University; University of Melbourne; Peter Doherty Institute; Nantes Universite; Institut National de la Sante et de la Recherche Medicale (Inserm); CHU de Nantes; Institut National de la Sante et de la Recherche Medicale (Inserm); Nantes Universite; CHU de Nantes; University of Queensland; University of Queensland; ARC Centre of Excellence for Innovations in Peptide & Protein Science; La Trobe University; Olivia Newton-John Cancer Research Institute; La Trobe University; University of Melbourne; Garvan Institute of Medical Research; University of New South Wales Sydney; University of Melbourne; Peter Doherty Institute; University of Melbourne; University of British Columbia; University of Melbourne
摘要：Mucosal-associated invariant T cells (MAIT cells) mediate tissue homeostasis and antimicrobial immunity. However, the cells that express major histocompatibility complex (MHC) class I-related protein 1 (MR1) and present microbial vitamin B-derived antigens (VitBAg) to MAIT cells remain unknown. We found that MR1 expression varied across tissues and cell types. Macrophages from the lung and peritoneal cavity expressed the highest levels of MR1 and were the most efficient at capturing and presen...
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作者：Frank, Nils; Chaudhari, Moreshwar B.; Leutzsch, Markus; Helmich-Paris, Benjamin; Bruzzese, Paolo Cleto; Nater, Darryl; Nothling, Nils; Schnegg, Alexander; Waldvogel, Siegfried R.; List, Benjamin
作者单位：Max Planck Society
摘要：The defossilization of the chemical industry is accelerated by the shift from petroleum- to biomass-based feedstocks. At the center stage are bioderived furans, from which valuable platform chemicals can be obtained exclusively through oxidative or reductive processes. By contrast, the conceptually straightforward redox-neutral hydrolysis of furan to succinaldehyde and 2-substituted furans to 1,4-ketoaldehydes has been considered unfeasible owing to their endergonicity and polymerization side ...
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作者：Jia, Longzhong; Li, Xiaohan; Yan, Yiming; Xu, Linhe; Guo, Jianbin; Wang, Weichao; Zhang, Weirong; Li, Lianyan; Shang, Borui; Zhang, Yiwei; Dang, Yashan; Zeng, Yuyan; Liao, Zhiyan; Liang, Ruijuan; Gu, Li; He, Chenyi; Long, Zhen; Hou, Hanqing; Zhou, Yuhan; Yan, Mingchao; Huang, Wei; Zhu, Lan; Mi, Da
作者单位：Tsinghua University; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College; Peking Union Medical College Hospital; Shandong First Medical University & Shandong Academy of Medical Sciences; Chinese Academy of Sciences; Center for Excellence in Brain Science and Intelligence Technology, CAS
摘要：The number and diversity of inhibitory neurons (INs) increased substantially during mammalian brain evolution. However, the generative mechanisms of the vast repertoire of human INs remain elusive. We performed spatial and single-cell transcriptomics of human medial ganglionic eminence (hMGE), a pivotal source of cortical and subpallial INs, and built the trajectories of hMGE-derived cells during brain development. We identified spatiotemporally and molecularly segregated progenitor cell popul...
