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作者：Shi, Qibin; Montgomery, David R.; Swann, Abigail L. S.; Cristea, Nicoleta C.; Williams, Ethan F.; You, Nan; Jeffery, Simon; Collins, Joe; Barrio, Ana Prada; Misiewicz, Paula A.; Nissen-Meyer, Tarje; Denolle, Marine A.
作者单位：Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Geology & Geophysics, CAS; Rice University; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of California System; University of California Santa Cruz; Purdue University System; Purdue University; Harper Adams University; University of Exeter
摘要：The impacts of farming practices on soil hydrodynamics are central to understanding agricultural landscapes covering almost half of the world's habitable land. Combining observations from distributed acoustic sensing with physics-based hydromechanical modeling, we tracked minute-resolution and meter-scale seismic and hydrological changes across agricultural fields with controlled histories of tillage and compaction. We show that dynamic capillary effects in soil govern transient stiffness and ...
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作者：James, Richard G.; Zhang, Ting-ting
作者单位：Seattle Children's Hospital; Seattle Children's Hospital; University of Washington; University of Washington Seattle
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作者：Tu, Weiming
作者单位：Nanyang Technological University; Nanyang Technological University; Danish Hydraulic Institute (DHI)
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作者：Hirano, Hisato; Tsuji, Naoko; Chiba, Shinobu; Nureki, Osamu
作者单位：University of Tokyo; Kyoto Sangyo University
摘要：Natural transformation is one of the major pathways of horizontal gene transfer in bacteria, enabling the acquisition of extracellular DNA and its integration into the host genome. ComEC is a membrane protein responsible for DNA translocation in this process, yet its precise function and structure have remained elusive. Here, we report cryo-electron microscopy structures of ComEC in DNA-free, single-stranded DNA (ssDNA)-bound, and double-stranded DNA (dsDNA)-bound forms, together with biochemi...
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作者：Zhang, Yue; Ouadah, Youcef; Liu, Yin; Kumar, Maya E.; Morck, Makenna M.; Krasnow, Mark A.
作者单位：Stanford Medicine; Stanford University; Stanford University; Stanford Medicine; Howard Hughes Medical Institute; Stanford University; Stanford University; Stanford Medicine; Stanford Medicine; Stanford University; California Institute of Technology; Howard Hughes Medical Institute
摘要：Stem cells proliferate after injury to repair damaged tissue, and chronic injury can promote cancer. However, the injury-activated signals and regulatory mechanisms, and their relationship to cancer, are poorly understood. Here, we identified insulin-like growth factor 2 (Igf2) as an injury-activated mitogen for lung neuroendocrine stem cells, which are facultative airway progenitors and a cell of origin of small-cell lung cancer in mice. Igf2 was constitutively produced by the stem cells but ...
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作者：Packin, Nizan Geslevich; Rabinovitz, Sharon
作者单位：City University of New York (CUNY) System; Baruch College (CUNY); University of Haifa; University of Haifa; University of Haifa; University of Haifa
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作者：Huang, Zhi; Yang, Qianqian; Li, Shenglong; Zhu, Xiaojia; Wang, He; Lin, Jixuan; Zhan, Yafeng; Wu, Yan; Wang, Zefang; Majka, Piotr; Qu, Haichao; Atapour, Nafiseh; Yang, Tao; Lin, Youning; Cui, Luman; Yao, Yong-Gang; Liang, Zhifeng; Liu, Zhen; Li, Chao; Wei, Wu; Zhou, Yi; Ma, Shaojie; Shen, Zhiming; Wei, Xiaoyu; Xu, Xun; Liu, Shiping; Li, Chengyu; Poo, Muming; Liu, Longqi; Rosa, Marcello G. P.; Sun, Yidi; Hao, Shijie; Liu, Cirong
作者单位：Chinese Academy of Sciences; Center for Excellence in Brain Science and Intelligence Technology, CAS; South China University of Technology; Lin Gang Laboratory; ShanghaiTech University; Chinese Academy of Sciences; Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Polish Academy of Sciences; Nencki Institute of Experimental Biology of the Polish Academy of Sciences; Monash University; Monash University; Shanghai Center for Brain Science & Brain-Inspired Technology
摘要：The principles organizing cellular diversity and connectivity in primate brains remain elusive. By integrating spatial transcriptomics, magnetic resonance imaging, and retrograde labeling in marmosets, we identified two opposing molecular gradients that undergo postnatal refinement, emanating from allocortices and primary sensory cortices, respectively. These gradients reconcile conflicting hypotheses on cortical expansion and characterize distinct cortical areas. Cortical gradients align with...
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作者：Das, Koushik; Reidy, Kate; Husain, Sajid; Park, Jong Ho; Jayakumar, Harishankar; Thampy, Vivek; Klewe, Christoph; Ramesh, Ramamoorthy; Minor, Andrew M.; Raja, Archana; Salahuddin, Sayeef
作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; United States Department of Energy (DOE); Stanford University; SLAC National Accelerator Laboratory; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley; University of California System; University of California Berkeley
摘要：Ferroelectricity at atomic-scale thickness would have important applications in next-generation electronics. Here, we report that a ferroelectric phase can be stabilized in titanium dioxide (TiO2) films, a commonly known dielectric that is widely used in semiconductor technologies, by reducing thickness to <3 nanometers. Importantly, this ferroelectricity persists down to 1-nanometer thickness, approximately twice the unit-cell dimension. This thickness-dependent dielectric-to-ferroelectric ph...
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作者：Savitsky, Zack
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作者：Dall'Armellina, Filippo
作者单位：University of Liverpool
