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作者：Offord, Catherine
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作者：Fox, Paul L.
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作者：Glassman, Caleb R.; Baek, Kheewoong; Hou, Gaopeng; Zeng, Qiru; Nardone, Christopher; Juergens, Kate B.; Fujimura, Eric; O'Leary, Colin N.; Li, Mamie Z.; Paulo, Joao A.; Fischer, Eric S.; Ding, Siyuan; Harper, J. Wade; Elledge, Stephen J.
作者单位：Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Howard Hughes Medical Institute; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard Medical School; Washington University (WUSTL); Saint Louis University; Harvard University; Harvard Medical School; Harvard University; Harvard Medical School; Harvard University; Harvard University; Harvard Medical School
摘要：Viruses are intracellular parasites that reprogram the host proteome to promote replication and evade immune recognition. We applied a virome-wide library of similar to 10,000 open reading frames to discover viral ubiquitin ligases, mapping their mechanisms of degradation and host substrates using targeted CRISPR screens and proteomics. These viral effectors could be classified as canonical ligases that mimic host E3s, hijackers that redirect host E3s, and noncanonical ligases that rewire cull...
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作者：Zhang, Mingjun; Han, Maoying; Hou, Yangfeng; Liu, Zixin; Wang, Yilian; Huang, Xiuzhen; Ho, Cheng Kiu; Qu, Hang; Wang, Qing-Dong; Ma, Xin; Lui, Kathy O.; Zhou, Bin
作者单位：Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS; Chinese University of Hong Kong; Prince of Wales Hospital Hong Kong; Jiangnan University; ShanghaiTech University
摘要：Coronary collateral arteries have been proposed to form de novo through artery reassembly, a process in which arterial endothelial cells (ECs) migrate away from preexisting arteries and reassemble into new arteries. Using genetic tools that trace arterial ECs, we found that their contribution to collaterals is modest. Dual genetic lineage tracing revealed that capillary ECs, rather than arterial ECs, serve as the major building blocks for de novo collaterals. The capillary-to-collateral conver...
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作者：Abid; Zhao, Luneng; Huang, Ju; Zheng, Yongjia; Sato, Yuta; Wang, Tianyu; Levshov, Dmitry; Wang, Lingfeng; Sun, Haiming; Lin, Qingyun; Han, Zhen; Yang, Chunxia; Nduwarugira, Bill Herve; Ma, Yicheng; Zheng, Yige; Wang, Hang; Ullah, Salman; Khan, Afzal; Zhang, Qi; Li, Wenbin; Gao, Junfeng; Ju, Bingfeng; Ding, Feng; Li, Yan; Herrebout, Wouter; Suenaga, Kazu; Maruyama, Shigeo; Yang, Huayong; Xiang, Rong
作者单位：Zhejiang University; Dalian University of Technology; Westlake University; Westlake University; National Institute of Advanced Industrial Science & Technology (AIST); University of Antwerp; University of Antwerp; University of Antwerp; Zhejiang University; Peking University; Hangzhou Dianzi University; Suzhou Laboratory; University of Tokyo; Nagoya University
摘要：Nanotubes represent an important class of crystalline materials, but controlling their structures, particularly chiralities, remains a fundamental challenge. In this work, we report a strategy for synthesizing transition metal dichalcogenide nanotubes with preferred armchair chirality. Tin disulfide, molybdenum disulfide, and tungsten disulfide nanotubes were formed with high yield and structural purity inside boron nitride nanotube channels. Atomic-resolution imaging, electron diffraction, an...
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作者：Hiraki, Takahiro; Masuda, Takahiko; Takatori, Sayuri; Schaden, Fabian; Bartokos, Michael; Beeks, Kjeld; Fukunaga, Yuta; Gruneis, Andreas; Guan, Ming; Kazakov, Georgy; LaGrange, Thomas; Leitner, Adrian; Morawetz, Ira; Ogake, Ryoichiro; Okai, Koichi; Pimon, Martin; Pressler, Martin; Riebner, Thomas; Sasao, Noboru; Schneider, Felix; Schumm, Thorsten; Shimizu, Kotaro; de Col, Luca Toscani; Sikorsky, Tomas; Yoshimi, Akihiro; Yoshimura, Koji
作者单位：Okayama University; Technische Universitat Wien; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Charles University Prague
摘要：M & ouml;ssbauer spectroscopy is widely used in chemistry, geology, and solid-state physics to probe the local physical and chemical environment of nuclei in materials. Here, we extended this technique into the optical range using a vacuum ultraviolet laser to probe the low-energy nuclear transitions of thorium-229 (229Th) doped in calcium fluoride (CaF2) crystals. We discovered four distinct doping sites for the thorium ions, determined the characteristic electric field gradients emerging fro...
