作者：LI, WK; HUI, YV
作者单位：Chinese University of Hong Kong
作者：WEI, LJ; SMYTHE, RT; MEHTA, CR
作者单位：George Washington University; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard Medical School
作者：BURNETT, R; KREWSKI, D; BLEUER, S
摘要：The standard statistical test for assessing adverse effects in rodent tumourigenicity experiments is based on a time-adjusted analysis of lethal and incidental tumours. This test is shown to arise as the sum of two score statistics for fatal and incidental lesions respectively, the former optimal against extreme value hazard alternatives and the latter optimal against logistic prevalence alternatives in terms of asymptotic relative efficiency in the Pitman sense. An efficiency robust test is d...
作者：HURVICH, CM; TSAI, CL
作者单位：University of California System; University of California Davis
