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作者：Liang, Feng; Paulo, Rui; Molina, German; Clyde, Merlise A.; Berger, Jim O.
作者单位：University of Illinois System; University of Illinois Urbana-Champaign; Universidade de Lisboa; Duke University
摘要：Zellner's g prior remains a popular conventional prior for use in Bayesian variable selection, despite several undesirable consistency issues. In this article we study mixtures of g priors as an alternative to default g priors that resolve many of the problems with the original formulation while maintaining the computational tractability that has made the g prior so popular. We present theoretical properties of the mixture g priors and provide real and simulated examples to compare the mixture...
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作者：Jin, Hui; Rubin, Donald B.
作者单位：Harvard University
摘要：Many double-blind placebo-controlled randomized experiments with active drugs suffer from complications beyond simple noncompliance. First, the compliance with assigned dose is often partial, with patients taking only part of the assigned dose, whether active or placebo. Second, the blinding may be imperfect in the sense that there may be detectable positive or negative side effects of the active drug, and consequently, simple compliance has to be extended to allow different compliances to act...
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作者：Zabell, S. L.
作者单位：Northwestern University; Northwestern University
摘要：This month marks the 100th anniversary of the appearance of William Sealey Gusset's celebrated article, The Probable Error of a Mean (Student 1908a). Gosset's elegant result represented the first in a series of exact, small-sample results that were developed by Gusset, Fisher, and others to form a central component of the modern theory of statistical inference. This review celebrates the centenary of Gosset's article by discussing both its background and its impact on statistical theory and pr...
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作者：Thomson, Madeleine C.
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作者：Zhu, Jun; Rasmussen, Jakob G.; Moller, Jesper; Aukema, Brian H.; Raffa, Kenneth F.
作者单位：University of Wisconsin System; University of Wisconsin Madison; Aalborg University; Natural Resources Canada; Canadian Forest Service; University of Northern British Columbia; University of Wisconsin System; University of Wisconsin Madison
摘要：Studies of forest declines are important, because they both reduce timber production and affect successional trajectories of landscapes and ecosystems. Of particular interest is the decline of red pines, which is characterized by expanding areas of dead and chlorotic trees in plantations throughout the Great Lakes region. Here we examine the impact of two bark beetle groups, red turpentine beetles and pine engraver bark beetles, on tree mortality and the subsequent gap formation over time in a...
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作者：Hunter, David R.; Goodreau, Steven M.; Handcock, Mark S.
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
摘要：We present a systematic examination of a real network data set using maximum likelihood estimation for exponential random graph models as well as new procedures to evaluate how well the models fit the observed networks. These procedures compare structural statistics of the observed network with the corresponding statistics on networks simulated from the fitted model. We apply this approach to the study of friendship relations among high school students from the National Longitudinal Study of A...
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作者：Edwards, A. W. F.
作者单位：University of Cambridge
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作者：Rice, Kenneth
作者单位：University of Washington; University of Washington Seattle
摘要：Two approaches dominate the analysis of highly stratified data sets: use of conditional likelihood and random-effects models. Conditioning is more traditional and has attractive robustness properties. Contemporary random-effects approaches rely more on accurate assumptions but can be applied to a larger class of problems. For pair-matched studies with arbitrary numbers of categorical covariates, we reconcile these two approaches, showing that the conditional approach has an exact interpretatio...
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作者：Lin, Haiqun; Feng, Ziding; Yu, Yan; Zheng, Yingye; Shivapurkar, Narayan; Gazdar, Adi F.
作者单位：Yale University; Fred Hutchinson Cancer Center; University System of Ohio; University of Cincinnati; University of Texas System; University of Texas Southwestern Medical Center
摘要：Alteration of gene methylation patterns has been reported to be involved in the early onsets of many human malignancies. Many exogenous risk factors, such as cigarette smoke, dietary additives, chemical exposures, radiation, and biologic agents including viral infection, are involved in the methylation pathways of cancers. We propose a multidimensional selective item response regression model to describe and test how a risk factor may alter molecular pathways involving aberrant methylation of ...
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作者：Dror, Hovav A.; Steinberg, David M.
作者单位：Tel Aviv University
摘要：We consider the problem of experimental design when the response is modeled by a generalized linear model (GLM) and the experimental plan can be determined sequentially. Most previous research on this problem has been limited either to one-factor, binary response experiments or to augmenting the design when there are already sufficient data to compute parameter estimates. We suggest a new procedure for the sequential choice of observations that offers five important advantages: (1) It can be a...
