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作者:Zhou, Hua; Li, Lexin; Zhu, Hongtu
作者单位:North Carolina State University; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina; University of North Carolina Chapel Hill
摘要:Classical regression methods treat covariates as a vector and estimate a corresponding vector of regression coefficients. Modem applications in medical imaging generate covariates of more complex form such as multidimensional arrays (tensors). Traditional statistical and computational methods are proving insufficient for analysis of these high-throughput data due to their ultrahigh dimensionality as well as complex structure. In this article, we propose a new family of tensor regression models...
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作者:Storlie, Curtis B.; Michalak, Sarah E.; Quinn, Heather M.; DuBois, Andrew J.; Wender, Steven A.; DuBois, David H.
作者单位:United States Department of Energy (DOE); Los Alamos National Laboratory; United States Department of Energy (DOE); Los Alamos National Laboratory
摘要:A soft error is an undesired change in an electronic device's state, for example, a bit flip in computer memory, that does not permanently affect its functionality. In microprocessor systems, neutron-induced soft errors can cause crashes and silent data corruption (SDC). SDC occurs when a soft error produces a computational result that is incorrect, without the system issuing a warning or error message. Hence, neutron-induced soft errors are a major concern for high performance computing platf...
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作者:Ip, Edward; Zhang, Qiang; Rejeski, Jack; Harris, Tammy; Kritchevsky, Stephen
作者单位:Wake Forest University; Wake Forest University; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA); Wake Forest University
摘要:At both the individual and societal levels, the health and economic burden of disability in older adults is enormous in developed countries, including the U.S. Recent studies have revealed that the disablement process in older adults often comprises episodic periods of impaired functioning and periods that are relatively free of disability, amid a secular and natural trend of decline in functioning. Rather than an irreversible, progressive event that is analogous to a chronic disease, disabili...
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作者:Li, Bo; Genton, Marc G.
作者单位:Purdue University System; Purdue University; King Abdullah University of Science & Technology
摘要:We propose a unified framework for testing a variety of assumptions commonly made about the structure of copulas, including symmetry, radial symmetry, joint symmetry, associativity and Archimedeanity, and max-stability. Our test is nonparametric and based on the asymptotic distribution of the empirical copula process. We perform simulation experiments to evaluate our test and conclude that our method is reliable and powerful for assessing common assumptions on the structure of copulas, particu...
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作者:Wang, Yueqing; Jiang, Xin; Yu, Bin; Jiang, Ming
作者单位:University of California System; University of California Berkeley; Peking University; University of California System; University of California Berkeley
摘要:Atmospheric aerosols can cause serious damage to human health and reduce life expectancy. Using the radiances observed by NASA's Multi-angle Imaging SpectroRadiometer (MISR), the current MISR operational algorithm retrieves aerosol optical depth (AOD) at 17.6 km resolution. A systematic study of aerosols and their impact on public health, especially in highly populated urban areas, requires finer-resolution estimates of AOD's spatial distribution. We embed MISR's operational weighted least squ...
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作者:Ghosh, Arpita; Wright, Fred A.; Zou, Fei
作者单位:Public Health Foundation of India; University of North Carolina; University of North Carolina Chapel Hill
摘要:It has been repeatedly shown that in case control association studies, analysis of a secondary trait that ignores the original sampling scheme can produce highly biased risk estimates. Although a number of approaches have been proposed to properly analyze secondary traits, most approaches fail to reproduce the marginal logistic model assumed for the original case control trait and/or do not allow for interaction between secondary trait and genotype marker on primary disease risk. In addition, ...
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作者:Vanderweele, Tyler J.; Hong, Guanglei; Jones, Stephanie M.; Brown, Joshua L.
作者单位:Harvard University; Harvard T.H. Chan School of Public Health; Harvard University; Harvard T.H. Chan School of Public Health; University of Chicago; Harvard University; Fordham University
摘要:Peer influence and social interactions can give rise to spillover effects in which the exposure of one individual may affect outcomes of other individuals. Even if the intervention under study occurs at the group or cluster level as in group-randomized trials, spillover effects can occur when the mediator of interest is measured at a lower level than the treatment. Evaluators who choose groups rather than individuals as experimental units in a randomized trial often anticipate that the desirab...
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作者:Zhu, Yunzhang; Shen, Xiaotong; Pan, Wei
作者单位:University of Minnesota System; University of Minnesota Twin Cities; University of Minnesota System; University of Minnesota Twin Cities
摘要:In high-dimensional regression, grouping pursuit and feature selection have their own merits while complementing each other in battling the curse of dimensionality. To seek a parsimonious model, we perform simultaneous grouping pursuit and feature selection over an arbitrary undirected graph with each node corresponding to one predictor. When the corresponding nodes are reachable from each other over the graph, regression coefficients can be grouped, whose absolute values are the same or close...
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作者:Murray, Jared S.; Dunson, David B.; Carin, Lawrence; Lucas, Joseph E.
作者单位:Duke University; Duke University; Duke University
摘要:Gaussian factor models have proven widely useful for parsimoniously characterizing dependence in multivariate data. There is rich literature on their extension to mixed categorical and continuous variables, using latent Gaussian variables or through generalized latent trait models accommodating measurements in the exponential family. However, when generalizing to non-Gaussian measured variables, the latent variables typically influence both the dependence structure and the form of the marginal...
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作者:Chakraborty, Avishek; Mallick, Bani K.; McClarren, Ryan G.; Kuranz, Carolyn C.; Bingham, Derek; Grosskopf, Michael J.; Rutter, Erica M.; Stripling, Hayes F.; Drake, R. Paul
作者单位:Texas A&M University System; Texas A&M University College Station; Texas A&M University System; Texas A&M University College Station; University of Michigan System; University of Michigan; Simon Fraser University
摘要:Radiation hydrodynamics and radiative shocks are of fundamental interest in the high-energy-density physics research due to their importance in understanding astrophysical phenomena such as supernovae. In the laboratory, experiments can produce shocks with fundamentally similar physics on reduced scales. However, the cost and time constraints of the experiment necessitate use of a computer algorithm to generate a reasonable number of outputs for making valid inference. We focus on modeling emu...