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作者:Cai, T. Tony; Liu, Weidong
作者单位:University of Pennsylvania; Shanghai Jiao Tong University; Shanghai Jiao Tong University
摘要:Multiple testing of correlations arises in many applications including gene coexpression network analysis and brain connectivity analysis. In this article, we consider large-scale simultaneous testing for correlations in both the one-sample and two-sample settings. New multiple testing procedures are proposed and a bootstrap method is introduced for estimating the proportion of the nulls falsely rejected among all the true nulls. We investigate the properties of the proposed procedures both th...
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作者:Fu, Wenjiang
作者单位:University of Houston System; University of Houston
摘要:This article considers a regression model on a Lexis diagram of an a x p table with a single response in each cell following a distribution in the exponential family. A regression model on the fixed effects of a rows, p columns, and a + p - 1 diagonals induces a singular design matrix and yields multiple estimators, leading to parameter identifiability problem in age-period-cohort analysis in social sciences, demography, and epidemiology, where assessment of secular trend in age, period, and b...
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作者:Schofield, Matthew R.; Barker, Richard J.; Gelman, Andrew; Cook, Edward R.; Briffa, Keith R.
作者单位:University of Kentucky; University of Otago; University of Otago; Columbia University; Columbia University; University of East Anglia
摘要:Quantifying long-term historical climate is fundamental to understanding recent climate change. Most instrumentally recorded climate data are only available for the past 200 years, so proxy observations from natural archives are often considered. We describe a model-based approach to reconstructing climate defined in terms of raw tree-ring measurement data that simultaneously accounts for nonclimatic and climatic variability. In this approach, we specify a joint model for the tree-ring data an...
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作者:Godolphin, J. D.
作者单位:University of Surrey
摘要:This article investigates the robustness of binary incomplete block designs against giving rise to a disconnected design in the event of observation loss. A link is established between the E-value of a planned design and the extent of observation loss that can be experienced while still guaranteeing an eventual design from which all treatment contrasts can be estimated. Patterns of missing observations covered include loss of entire blocks and loss of individual observations. Simple bounds are...
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作者:Cheng, Ming-Yen; Honda, Toshio; Zhang, Jin-Ting
作者单位:National Taiwan University; Hitotsubashi University; National University of Singapore
摘要:Varying coefficient models have numerous applications in a wide scope of scientific areas. While enjoying nice interpretability, they also allow for flexibility in modeling dynamic impacts of the covariates. But, in the new era of big data, it is challenging to select the relevant variables when the dimensionality is very large. Recently, several works are focused on this important problem based on sparsity assumptions; they are subject to some limitations, however. We introduce an appealing f...
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作者:Li, Gang; Yang, Qing
作者单位:University of California System; University of California Los Angeles; Duke University
摘要:This article develops joint inferential methods for,the cause-specific hazard function and the cumulative incidence function of a specific type of failure to assess the effects of a variable on the time to the type of failure of interest in the presence of competing risks. Joint inference for the two functions are needed in practice because (i) they describe different characteristics of a given type of failure, (ii) they do not uniquely determine each other, and (iii) the effects of a variable...
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作者:Brown, Lawrence D.; Johnson, Kory D.
作者单位:University of Pennsylvania
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作者:Cervone, Daniel; D'Amour, Alex; Bornn, Luke; Goldsberry, Kirk
作者单位:New York University
摘要:Basketball games evolve continuously in space and time as players constantly interact with their teammates, the opposing team, and the ball. However, current analyses of basketball outcomes rely on discretized summaries of the game that reduce such interactions to tallies of points, assists, and similar events. In this article, we propose a framework for using optical player tracking data to estimate, in real time, the expected number of points obtained by the end of,a possession. This quantit...
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作者:Greven, Sonja; Scheipl, Fabian
作者单位:University of Munich
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作者:Zhao, Yize; Chung, Matthias; Johnson, Brent A.; Moreno, Carlos S.; Long, Qi
作者单位:Cornell University; Virginia Polytechnic Institute & State University; University of Rochester; Emory University; Emory University
摘要:Our work is motivated by a prostate cancer study aimed at identifying mRNA and miRNA biomarkers that are predictive of cancer recurrence after prostatectomy. It has been shown in the literature that incorporating known biological information on pathway memberships and interactions among biomarkers improves feature selection of high-dimensional biomarkers in relation to disease risk. Biological information is often represented by graphs or networks, in which biomarkers are represented by nodes ...