-
作者：Asadi, Peiman; Davison, Anthony C.; Engelke, Sebastian
作者单位：Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要：Max-stable processes are the natural extension of the classical extreme-value distributions to the functional setting, and they are increasingly widely used to estimate probabilities of complex extreme events. In this paper we broaden them from the usual situation in which dependence varies according to functions of Euclidean distance to situations in which extreme river discharges at two locations on a river network may be dependent because the locations are flow-connected or because of commo...
-
作者：Schofield, Lynne Steuerle
作者单位：Swarthmore College
摘要：This paper represents a methodological-substantive synergy. A new model, the Mixed Effects Structural Equations (MESE) model which combines structural equations modeling and item response theory, is introduced to attend to measurement error bias when using several latent variables as predictors in generalized linear models. The paper investigates racial and gender disparities in STEM retention in higher education. Using the MESE model with 1997 National Longitudinal Survey of Youth data, I fin...
-
作者：Winderbaum, Lyron J.; Koch, Inge; Gustafsson, Ove J. R.; Meding, Stephan; Hoffmann, Peter
作者单位：University of Adelaide
摘要：Imaging mass spectrometry (IMS) has transformed proteomics by providing an avenue for collecting spatially distributed molecular data. Mass spectrometry data acquired with matrix assisted laser desorption ionization (MALDI) IMS consist of tens of thousands of spectra, measured at regular grid points across the surface of a tissue section. Unlike the more standard liquid chromatography mass spectrometry, MALDI-IMS preserves the spatial information inherent in the tissue. Motivated by the need t...
-
作者：Fanshawe, T. R.; Chapman, C. M.; Crick, T.
作者单位：University of Oxford
摘要：Although the lymphatic system is clearly linked to the metastasis of most human carcinomas, the mechanisms by which lymphangiogenesis occurs in response to the presence of carcinoma remain unclear. Hierarchical models are presented to investigate the properties of lymphatic vessel production in 2997 fields taken from 20 individuals with invasive carcinoma, 21 individuals with cervical intraepithelial neoplasia and 21 controls. Such data demonstrate a high degree of correlation within tumour sa...
-
作者：Han, Shengtong; Zhang, Hongmei; Lockett, Gabrielle A.; Mukherjee, Nandini; Holloway, John W.; Karmaus, Wilfried
作者单位：University of Memphis; University of Southampton; University of Southampton
摘要：This paper explores the transgenerational DNA methylation pattern ( DNA methylation transmitted from one generation to the next) via a clustering approach. Beta regression is employed to model the transmission pattern from parents to their offsprings at the population level. To facilitate this goal, an expectation maximization algorithm for parameter estimation along with a BIC criterion to determine the number of clusters is proposed. Applying our method to the DNA methylation data composed o...
-
作者：Zanella, Giacomo
作者单位：University of Warwick
摘要：Common cluster models for multi-type point processes model the aggregation of points of the same type. In complete contrast, in the study of Anglo-Saxon settlements it is hypothesized that administrative clusters involving complementary names tend to appear. We investigate the evidence for such a hypothesis by developing a Bayesian Random Partition Model based on clusters formed by points of different types (complementary clustering). As a result, we obtain an intractable posterior distributio...
-
作者：Sun, Ying; Stein, Michael L.
作者单位：King Abdullah University of Science & Technology; University of Chicago
摘要：Modeling a precipitation field is challenging due to its intermittent and highly scale-dependent nature. Motivated by the features of high-frequency precipitation data from a network of rain gauges, we propose a threshold space-time t random field (tRF) model for 15-minute precipitation occurrences. This model is constructed through a space-time Gaussian random field (GRF) with random scaling varying along time or space and time. It can be viewed as a generalization of the purely spatial tRF, ...
-
作者：Guseo, Renato; Mortarino, Cinzia
作者单位：University of Padua
摘要：The study of competition among brands in a common category is an interesting strategic issue for involved firms. Sales monitoring and prediction of competitors' performance represent relevant tools for management. In the pharmaceutical market, the diffusion of product knowledge plays a special role, different from the role it plays in other competing fields. This latent feature naturally affects the evolution of drugs' performances in terms of the number of packages sold. In this paper, we pro...
