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作者:Koslovsky, Matthew D.; Hoffman, Kristi L.; Daniel, Carrie R.; Vannucci, Marina
作者单位:Rice University; Baylor College of Medicine; University of Texas System; UTMD Anderson Cancer Center
摘要:One of the major research questions regarding human microbiome studies is the feasibility of designing interventions that modulate the composition of the microbiome to promote health and to cure disease. This requires extensive understanding of the modulating factors of the microbiome, such as dietary intake, as well as the relation between microbial composition and phenotypic outcomes, such as body mass index (BMI). Previous efforts have modeled these data separately, employing two-step appro...
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作者:Paul, Subhadeep; Chen, Yuguo
作者单位:University System of Ohio; Ohio State University; University of Illinois System; University of Illinois Urbana-Champaign
摘要:To analyze data from multisubject experiments in neuroimaging studies, we develop a modeling framework for joint community detection in a group of related networks that can be considered as a sample from a population of networks. The proposed random effects stochastic block model facilitates the study of group differences and subject-specific variations in the community structure. The model proposes a putative mean community structure, which is representative of the group or the population und...
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作者:MacDonald, Iain L.
作者单位:University of Cape Town
摘要:The problem of fitting a folded normal distribution by maximum likelihood has been described as 'not straightforward', and alternatives such as EM proposed. We suggest here that it is in fact straightforward to fit such a distribution by direct numerical maximization of the likelihood. We demonstrate this in an example. The relevant R code is included.
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作者:Schliep, Erin M.; Collins, Sarah M.; Rojas-Salazar, Shirley; Lottig, Noah R.; Stanley, Emily H.
作者单位:University of Missouri System; University of Missouri Columbia; University of Wyoming; University of Wisconsin System; University of Wisconsin Madison
摘要:Concentrations of nitrogen provide a critical metric for understanding ecosystem function and water quality in lakes. However, varying approaches for quantifying nitrogen concentrations may bias the comparison of water quality across lakes and regions. Different measurements of total nitrogen exist based on its composition (e.g., organic versus inorganic, dissolved versus particulate), which we refer to as nitrogen species. Fortunately, measurements of multiple nitrogen species are often colle...
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作者:Fuglstad, Geir-Arne; Castruccio, Stefano
作者单位:Norwegian University of Science & Technology (NTNU); University of Notre Dame
摘要:Modern climate models pose an ever-increasing storage burden to computational facilities, and the upcoming generation of global simulations from the next Intergovernmental Panel on Climate Change will require a substantial share of the budget of research centers worldwide to be allocated just for this task. A statistical model can be used as a means to mitigate the storage burden by providing a stochastic approximation of the climate simulations. Indeed, if a suitably validated statistical mod...