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作者:Keeney, Ralph L.; See, Kelly E.; von Winterfeldt, Detlof
作者单位:Duke University; New York University; University of Southern California
摘要:This paper describes a decision analysis methodology to evaluate academic programs. It avoids the shortcomings of the well-known evaluations of universities and academic programs produced by the public media. In addition to evaluating traditional departments and schools, the methodology is designed to evaluate interdisciplinary programs or fields that typically span many areas of a university, such as operations research, risk analysis, and decision science. We first discuss general principles...
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作者:Agur, Zvia; Hassin, Refael; Levy, Sigal
作者单位:Tel Aviv University; Academic College of Tel Aviv Yaffo
摘要:We develop a method for computing efficient patient-specific drug protocols. Using this method, we identify two general categories of anticancer drug protocols, depending on the temporal cycle parameters of the host and cancer cells: a one-time intensive treatment, or a series of nonintensive treatments. Our method is based on a theoretical and experimental work showing that treatment efficacy can be improved by determining the dosing frequency on the drug-susceptible target and host cell-cycl...
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作者:Keha, Ahmet B.; de Farias, Ismael R., Jr.; Nemhauser, George L.
作者单位:Arizona State University; Arizona State University-Tempe; State University of New York (SUNY) System; University at Buffalo, SUNY; University System of Georgia; Georgia Institute of Technology
摘要:We give a branch-and-cut algorithm for solving linear programs (LPs) with continuous separable piecewise-linear cost functions (PLFs). Models for PLFs use continuous variables in special-ordered sets of type 2 (SOS2). Traditionally, SOS2 constraints are enforced by introducing auxiliary binary variables and other linear constraints on them. Alternatively, we can enforce SOS2 constraints by branching on them, thus dispensing with auxiliary binary variables. We explore this approach further by s...
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作者:Caldentey, Rene; Wein, Lawrence M.
作者单位:New York University; Stanford University
摘要:Motivated by recent electronic marketplaces, we consider a single-product make-to-stock manufacturing system that uses two alternative selling channels: long-term contracts and a spot market of electronic orders. At time 0, the risk-averse manufacturer selects the long-term contract price, at which point buyers choose one of the two channels. The resulting long-term contract demand is a deterministic fluid, while the spot-market demand is modeled as a stochastic renewal process. An exponential...
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作者:Ata, Baris
作者单位:Northwestern University
摘要:As a model of make-to-order production, we consider an admission control problem for a multiclass, single-server queue. The production system serves multiple demand streams, each having a rigid due-date lead time. To meet the due-date constraints, a system manager may reject orders when a backlog of work is judged to be excessive, thereby incurring lost revenues. The system manager strives to minimize long-run average lost revenues by dynamically making admission control and sequencing decisio...
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作者:Netessine, Serguei; Savin, Sergei; Xiao, Wenqiang
作者单位:University of Pennsylvania; Columbia University; New York University
摘要:We consider the problem of dynamically cross-selling products (e.g., books) or services (e.g., travel reservations) in the e-commerce setting. In particular, we look at a company that faces a stream of stochastic customer arrivals and may offer each customer a choice between the requested product and a package containing the requested product as well as another product, what we call a packaging complement. Given consumer preferences and product inventories, we analyze two issues: (1) how to se...
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作者:Maglaras, Constantinos
作者单位:Columbia University
摘要:Motivated by the recent adoption of tactical pricing strategies in manufacturing settings, this paper studies a problem of dynamic pricing for a multiproduct make-to-order system. Specifically, for a multiclass M-n/M/1 queue with controllable arrival rates, general demand curves, and linear holding costs, we study the problem of maximizing the expected revenues minus holding costs by selecting a pair of dynamic pricing and sequencing policies. Using a deterministic and continuous (fluid model)...
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作者:Armbruster, Dieter; Marthaler, Daniel E.; Ringhofer, Christian; Kempf, Karl; Jo, Tae-Chang
作者单位:Arizona State University; Arizona State University-Tempe; Arizona State University; Arizona State University-Tempe; Intel Corporation; Intel USA; Inha University
摘要:High-volume, multistage continuous production flow through a re-entrant factory is modeled through a conservation law for a continuous-density variable on a continuous-production line augmented by a state equation for the speed of the production along the production line. The resulting nonlinear, nonlocal hyperbolic conservation law allows fast and accurate simulations. Little's law is built into the model. It is argued that the state equation for a re-entrant factory should be nonlinear. Comp...
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作者:Brahimi, Nadjib; Dauzere-Peres, Stephane; Najid, Najib M.
作者单位:Centre National de la Recherche Scientifique (CNRS); IMT - Institut Mines-Telecom; IMT Atlantique; Nantes Universite; Ecole Centrale de Nantes; IMT - Institut Mines-Telecom; Mines Saint-Etienne; Centre National de la Recherche Scientifique (CNRS)
摘要:This research concerns a new family of capacitated multi-item lot-sizing problems, namely, lot-sizing problems with time windows. Two classes of the problem are analyzed and solved using different Lagrangian heuristics. Capacity constraints and a subset of time window constraints are relaxed resulting in particular single-item time window problems that are solved in polynomial time. Other relaxations leading to the classical Wagner-Whitin problem are also tested. Several smoothing heuristics a...
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作者:Cooper, William L.; Homem-de-Mello, Tito; Kleywegt, Anton J.
作者单位:University of Minnesota System; University of Minnesota Twin Cities; Northwestern University; University System of Georgia; Georgia Institute of Technology
摘要:The spiral-down effect occurs when incorrect assumptions about customer behavior cause high-fare ticket sales, protection levels, and revenues to systematically decrease over time. If an airline decides how many seats to protect for sale at a high fare based on past high-fare sales, while neglecting to account for the fact that availability of low-fare tickets will reduce high-fare sales, then high-fare sales will decrease, resulting in lower future estimates of high-fare demand. This subseque...