Why the X chromosome is rich in L1 mobile elements

• 成果类型: Editorial Material
• 署名作者: Doucet, Aurelien J.; Cristofari, Gael
• 署名单位: Institut National de la Sante et de la Recherche Medicale (Inserm); CHU Nice; Universite Cote d'Azur; Centre National de la Recherche Scientifique (CNRS)
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-8075; 1095-9203
• DOI: 10.1126/science.aej3543
• 发表日期: 2026-07-30
• 页码: 459-460
• 关键词: line-1 retrotransposition; inactivation; dna

摘要

Preferential insertion into the late-replicating inactive X explains L1 accumulation in this chromosome