CO2 upgrading into bioproducts using a two-step abiotic-biotic system

• 成果类型: Article
• 署名作者: Lee, Geonhui; Jo, Hye -Jin; Choi, Jihoon; Guzman, Maria Fonseca; Shan, Yu; Le, Han K. D.; Feijoo, Julian; Soland, Nathan; Clark, Douglas S.; Yang, Peidong
• 署名单位: University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-15226
• DOI: 10.1073/pnas.2512565122
• 发表日期: 2025-08-26
• 关键词: alcaligenes-eutrophus; multicarbon products; electrolysis; biomass; energy; 1-butanol; catalysts; PATHWAY; acetate; ethanol

摘要

The valorization of CO2 to chemicals beyond C1-2 products is receiving significant interest; however, the direct electrosynthesis of C-n molecules (n > 4) remains a challenge. Here, we present a two-step abiotic-biotic system for upgrading CO2 into the biopolymer, poly(3-hydroxybutyrate). In the electrolysis system, CO2 is converted into C-2 oxygenates using a Cu-Ag tandem electrocatalyst. The electrolysis process generates a liquid stream containing similar to 200 mM acetate in a bio-compatible electrolyte. This electrosynthesized acetate is then fed to a bioreactor, where the substrate is upgraded by Cupriavidus necator to biopolymer with a maximum rate of 32 +/- 3.5 mg L-1 h(-1). We further demonstrate the purification of the resulting biopolymer into a powder. The high productivity of the abiotic-biotic system demonstrates its feasibility for sustainable chemical manufacturing.