Object-directed action representations are componentially built in parietal cortex

• 成果类型: Article
• 署名作者: Caglar, Leyla Roksan; Walbrin, Jon; Akwayena, Emefa; Almeida, Jorge; Mahon, Bradford Z.
• 署名单位: Carnegie Mellon University; Universidade de Coimbra; Universidade de Coimbra; Carnegie Mellon University; University of Rochester
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-14498
• DOI: 10.1073/pnas.2421032122
• 发表日期: 2025-08-26
• 关键词: face-selective cortex; tool-use; supramarginal gyrus; motor cortex; RECOGNITION; form; manipulation; regions; apraxia; dissociation

摘要

The inferior parietal lobule supports action representations that are necessary to grasp and 71-78 (2004)]. The supramarginal gyrus (SMG) is a structure within the inferior parietal lobule that specifically processes object-directed patterns of manipulation during functional object use. Here, we demonstrate that neural representations of complex object-directed actions in the SMG can be predicted by a linear encoding model that componentially builds complex actions from an empirically defined set of kinematic synergies. Each kinematic synergy represents a unique combination of finger, hand, wrist, and arm postures and movements. Control analyses demonstrate that models based on image-computable in the SMG. We also show that SMG activity is specifically modulated by kinematic (as visually relevant, nature of the representations supported by the SMG aligns with findings from neuropsychological studies of upper limb apraxia. These findings support a model in which kinematic synergies are the basic unit of representation, out of which the SMG componentially builds object-directed actions. In combination with other findings [Q. are related to complex object-directed actions in a similar way to how articulatory and voicing features combine to form phonological segments in spoken language production.