Hippocampal blood oxygenation predicts choices about everyday consumer experiences: A deep-learning approach

• 成果类型: Article
• 署名作者: Basavaraj, Chinmai; Reimann, Martin; Barnard, Kobus; Nadel, Lynn
• 署名单位: University of Arizona; University of Arizona; University of Arizona
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-13799
• DOI: 10.1073/pnas.2421905122
• 发表日期: 2025-07-07
• 关键词: individual-differences; molecular-biology; neural responses; decision-making; prospect-theory; memory storage; activation; aversion; biases; genes

摘要

This research investigates the neurophysiological mechanisms of experiential versus monetary choices under risk. While ventral striatum and insula activity are instrumental in predicting monetary choices, we find that hippocampal activity plays a key role in predicting experiential choices, which we theorize is due to its role in retrieving autobiographical memories. This neurophysiological differentiation clarifies observed variations in risk preferences between experiential and monetary prospects and highlights the importance of domain-specific neurophysiological processes in shaping human decision-making.