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作者：Gong, Yan; Huser, Raphael
作者单位：King Abdullah University of Science & Technology
摘要：Since the inception of Bitcoin in 2008, cryptocurrencies have played an increasing role in the world of e-commerce, but the recent turbulence in the cryptocurrency market in 2018 has raised some concerns about their stability and associated risks. For investors it is crucial to uncover the dependence relationships between cryptocurrencies for a more resilient portfolio diversification. Moreover, the stochastic behavior in both tails is important, as long positions are sensitive to a decrease i...
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作者：Moreira, Guido A.; Gamerman, Dani
作者单位：Universidade do Minho; Universidade Federal do Rio de Janeiro
摘要：This paper provides an exact modeling approach for the analysis of presence-only ecological data. Our proposal is also based on frequently used inhomogeneous Poisson processes but does not rely on model approximations, unlike other approaches. Exactness is achieved via a data augmentation scheme. One of the augmented processes can be interpreted as the unobserved occurrences of the relevant species, and its posterior distribution can be used to make predictions of the species over the region o...
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作者：Yarger, Drew; Stoev, Stilian; Hsing, Tailen
作者单位：University of Michigan System; University of Michigan
摘要：The Argo data is a modern oceanography dataset that provides unprecedented global coverage of temperature and salinity measurements in the upper 2000 meters of depth of the ocean. We study the Argo data from the perspective of functional data analysis (FDA). We develop spatiotemporal functional kriging methodology for mean and covariance estimation to predict temperature and salinity at a fixed location as a smooth function of depth. By combining tools from FDA and spatial statistics, includin...
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作者：Benedetti, Marco H.; Berrocal, Veronica J.; Little, Roderick J.
作者单位：University System of Ohio; Ohio State University; Nationwide Childrens Hospital; Research Institute at Nationwide Children's Hospital; University of Michigan System; University of Michigan
摘要：Understanding the effects of social determinants of health on health out-comes requires data on characteristics of the neighborhoods in which sub-jects live. However, estimates of these characteristics are often aggregated over space and time in a fashion that diminishes their utility. Take, for exam-ple, estimates from the American Community Survey (ACS), a multiyear na-tionwide survey administered by the U.S. Census Bureau: estimates for small municipal areas are aggregated over 5-year perio...
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作者：Jiang, Lingjing; Elrod, Chris; Kim, Jane J.; Swafford, Austin D.; Knight, Rob; Thompson, Wesley K.
作者单位：University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要：Microbiome researchers often need to model the temporal dynamics of multiple complex, nonlinear outcome trajectories simultaneously. This motivates our development of multivariate Sparse Functional Principal Components Analysis (mSFPCA), extending existing SFPCA methods to simultaneously characterize multiple temporal trajectories and their interrelationships. As with existing SFPCA methods, the mSFPCA algorithm characterizes each trajectory as a smooth mean plus a weighted combination of the ...
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作者：Warren, Joshua L.; Chang, Howard H.; Warren, Lauren K.; Strickland, Matthew J.; Darrow, Lyndsey A.; Mulholland, James A.
作者单位：Yale University; Emory University; Research Triangle Institute; Nevada System of Higher Education (NSHE); University of Nevada Reno; University System of Georgia; Georgia Institute of Technology
摘要：Understanding the role of time-varying pollution mixtures on human health is critical as people are simultaneously exposed to multiple pollutants during their lives. For vulnerable subpopulations who have well-defined exposure periods (e.g., pregnant women), questions regarding critical windows of exposure to these mixtures are important for mitigating harm. We extend critical window variable selection (CWVS) to the multipollutant setting by introducing CWVS for mixtures (CWVSmix), a hierarchi...
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作者：Chkrebtii, Oksana A.; Garcia, Yury E.; Capistran, Marcos A.; Noyola, Daniel E.
作者单位：University System of Ohio; Ohio State University; CIMAT - Centro de Investigacion en Matematicas; Universidad Autonoma de San Luis Potosi
摘要：Before the current pandemic, influenza and respiratory syncytial virus (RSV) were the leading etiological agents of seasonal acute respiratory infections (ARI) around the world. In this setting, medical doctors typically based the diagnosis of ARI on patients' symptoms alone and did not routinely conduct virological tests necessary to identify individual viruses, limiting the ability to study the interaction between multiple pathogens and to make public health recommendations. We consider a st...
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作者：Santos-Fernandez, Edgar; Denti, Francesco; Mengersen, Kerrie; Mira, Antonietta
作者单位：Queensland University of Technology (QUT); University of California System; University of California Irvine; Universita della Svizzera Italiana
摘要：Following the introduction of high-resolution player tracking technology, a new range of statistical analysis has emerged in sports, specifically in basketball. However, such high-dimensional data are often challenging for statistical inference and decision making. In this article we employ a state-of-the-art Bayesian mixture model that allows the estimation of heterogeneous intrinsic dimension (ID) within a dataset, and we propose some theoretical enhancements. Informally, the ID can be seen ...
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作者：Schumacher, Austin E.; McCormicK, Tyler H.; Wakefield, Jon; Chu, Yue; Perin, Jamie; Villavicencio, Francisco; Simon, Noah; Liu, Li
作者单位：University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University System of Ohio; Ohio State University; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health
摘要：In order to implement disease-specific interventions in young age groups, policy makers in low- and middle-income countries require timely and accurate estimates of age- and cause-specific child mortality. High-quality data is not available in settings where these interventions are most needed, but there is a push to create sample registration systems that collect detailed mortality information. Current methods that estimate mortality from this data employ multistage frameworks without rigorou...
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作者：Saha, Abhisek; HA, Min Jin; Acharyya, Satwik; Baladandayuthapani, Veerabhadran
作者单位：National Institutes of Health (NIH) - USA; Yonsei University; Yonsei University Health System; University of Michigan System; University of Michigan
摘要：The development and clinical implementation of evidence-based preci-sion medicine strategies has become a realistic possibility, primarily due to the rapid accumulation of large-scale genomics and pharmacological data from diverse model systems: patients, cell lines and drug perturbation studies. We introduce a novel Bayesian modeling framework called the individualized theRapeutic index (iRx) model to integrate high-throughput pharmacoge-nomic data across model systems. Our iRx model achieves...
