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作者：Storlie, Curtis B.; Reich, Brian J.; Rust, William N.; Ticknor, Lawrence O.; Bonnie, Amanda M.; Montoya, Andrew J.; Michalak, Sarah E.
作者单位：United States Department of Energy (DOE); Los Alamos National Laboratory; North Carolina State University; United States Department of Energy (DOE); Los Alamos National Laboratory
摘要：Los Alamos National Laboratory is home to many large supercomputing clusters. These clusters require an enormous amount of power (approximate to 500-2000 kW each), and most of this energy is converted into heat. Thus, cooling the components of the supercomputer becomes a critical and expensive endeavor. Recently, a project was initiated to investigate the effect that changes to the cooling system in a machine room had on three large machines that were housed there. Coupled with this goal was t...
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作者：Luo, Ruiyan; Qi, Xin
作者单位：University System of Georgia; Georgia State University; University System of Georgia; Georgia State University
摘要：We consider functional linear regression models with a functional response and multiple functional predictors, with the goal of finding the best finite-dimensional approximation to the signal part of the response function. Defining the integrated squared correlation coefficient between a random variable and a random function, we propose to solve a penalized generalized functional eigenvalue problem, whose solutions satisfy that projections on the original predictors generate new scalar uncorre...
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作者：Marra, Giampiero; Radice, Rosalba; Barnighausen, Till; Wood, Simon N.; McGovern, Mark E.
作者单位：University of London; University College London; University of London; Birkbeck University London; Harvard University; Harvard T.H. Chan School of Public Health; University of Kwazulu Natal; University of Bristol; Queens University Belfast
摘要：Estimates,of HIV prevalence are important for policy to establish the health status of a country's population and to evaluate,he effectiveness of population-based, interventions and campaigns. However, participation rates in testing for surveillance conducted as part of household surveys, on which, many of these estimates are based, can be low. HIV positive individuals may be less likely to participate because they fear disclosure, in which case estimates, obtained using conventional approache...
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作者：Strait, Justin; Kurtek, Sebastian; Bartha, Emily; MacEachern, Steven N.
作者单位：University System of Ohio; Ohio State University
摘要：Various approaches to statistical shape analysis exist in current literature. They mainly differ in the representations, metrics, and/or methods for alignment of shapes. One such approach is based on landmarks, that is, mathematically or structurally meaningful points, which ignores the remaining outline information. Elastic shape analysis, a more recent approach, attempts to fix this by using a special functional representation of the parametrically defined outline to perform shape registrati...
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作者：Zhang, Xianyang; Cheng, Guang
作者单位：Texas A&M University System; Texas A&M University College Station; Purdue University System; Purdue University
摘要：This article proposes a bootstrap-assisted procedure to conduct simultaneous inference for high-dimensional sparse linear models based on the recent desparsifying Lasso estimator. Our procedure allows the dimension of the parameter vector of interest to be exponentially larger than sample size, and it automatically accounts for the dependence within the desparsifying Lasso estimator. Moreover, our simultaneous testing method can be naturally coupled with the margin screening to enhance its pow...
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作者：Wood, Simon N.; Li, Zheyuan; Shaddick, Gavin; Augustin, Nicole H.
作者单位：University of Bristol; University of Bath
摘要：We develop scalable methods for fitting penalized regression spline based generalized additive models with of the order of 104 coefficients to up to 108 data. Computational feasibility rests on: (i) a new iteration scheme for estimation of model coefficients and smoothing parameters, avoiding poorly scaling matrix operations; (ii) parallelization of the iteration's pivoted block Cholesky and basic matrix operations; (iii) the marginal discretization of model covariates to reduce memory footpri...
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作者：Zhou, Xin; Mayer-Hamblett, Nicole; Khan, Umer; Kosorok, Michael R.
作者单位：University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; Seattle Children's Hospital; Cystic Fibrosis Foundation; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine
摘要：Personalized medicine has received increasing attention among statisticians, computer scientists, and clinical practitioners. A major component of personalized medicine is the estimation of individualized treatment rules (ITRs). Recently, Zhao etal. proposed outcome weighted learning (OWL) to construct ITRs that directly optimize the clinical outcome. Although OWL opens the door to introducing machine learning techniques to optimal treatment regimes, it still has some problems in performance. ...
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作者：Bi, Xuan; Qu, Annie; Wang, Junhui; Shen, Xiaotong
作者单位：University of Illinois System; University of Illinois Urbana-Champaign; Yunnan University; City University of Hong Kong; University of Minnesota System; University of Minnesota Twin Cities
摘要：In recent years, there has been a growing demand to develop efficient recommender systems which track users' preferences and recommend potential items of interest to users. In this article, we propose a group-specific method to use dependency information from users and items which share similar characteristics under the singular value decomposition framework. The new approach is effective for the cold-start problem, where, in the testing set, majority responses are obtained from new users or f...
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作者：Little, Roderick J.; Rubin, Donald B.; Zangeneh, Sahar Z.
作者单位：University of Michigan System; University of Michigan; Harvard University; Fred Hutchinson Cancer Center
摘要：For likelihood-based inferences from data with missing values, models are generally needed for both the data and the missing-data mechanism. However, modeling the mechanism can be challenging, and parameters are often poorly identified. Rubin in 1976 showed that for likelihood and Bayesian inference, sufficient conditions for ignoring the missing data mechanism are (a) the missing data are missing at random (MAR), in the sense that missingness does not depend on the missing values after condit...
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作者：Ni, Yang; Stingo, Francesco C.; Baladandayuthapani, Veerabhadran
作者单位：University of Texas System; UTMD Anderson Cancer Center; University of Texas System; University of Texas Austin; University of Florence
摘要：Multi-dimensional data constituted by measurements along multiple axes have emerged across many scientific areas such as genomics and cancer surveillance. A common objective is to investigate the conditional dependencies among the variables along each axes taking into account multi-dimensional structure of the data. Traditional multivariate approaches are unsuitable for such highly structured data due to inefficiency, loss of power, and lack of interpretability. In this article, we propose a n...
