6642期

最新文章

• Brain activity of diving seals reveals short sleep cycles at depth AI翻译
  作者：Kendall-Bar, Jessica M.; Williams, Terrie M.; Mukherji, Ritika; Lozano, Daniel A.; Pitman, Julie K.; Holser, Rachel R.; Keates, Theresa; Beltran, Roxanne S.; Robinson, Patrick W.; Crocker, Daniel E.; Adachi, Taiki; Lyamin, Oleg I.; Vyssotski, Alexei L.; Costa, Daniel P.
  作者单位：University of California System; University of California San Diego; Scripps Institution of Oceanography; University of California System; University of California Santa Cruz; University of Oxford; University of California System; University of California Santa Cruz; University of California System; University of California Santa Cruz; California State University System; Sonoma State University; University of California System; University of California Los Angeles; Russian Academy of Sciences; Saratov Scientific Center of the Russian Academy of Sciences; Severtsov Institute of Ecology & Evolution; University of Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich
  摘要：Sleep is a crucial part of the daily activity patterns of mammals. However, in marine species that spend months or entire lifetimes at sea, the location, timing, and duration of sleep may be constrained. To understand how marine mammals satisfy their daily sleep requirements while at sea, we monitored electroencephalographic activity in wild northern elephant seals (Mirounga angustirostris) diving in Monterey Bay, California. Brain-wave patterns showed that seals took short (less than 20 minut...
• The era of the intoxicated experimentalist A historian revisits psychoactive self-experimentation?s 19th-century heyday AI翻译
  作者：Richert, Lucas
  作者单位：University of Wisconsin System; University of Wisconsin Madison
• Scaling information pathways in optical fibers by topological confinement AI翻译
  作者：Ma, Zelin; Kristensen, Poul; Ramachandran, Siddharth
  作者单位：Boston University; Furukawa Electric
  摘要：Spatial mode-count scalability in optical fibers is of paramount importance for addressing the upcoming information-capacity crunch, reducing energy consumption per bit, and for enabling advanced quantum computing networks, but this scalability is severely limited by perturbative mode mixing. We show an alternative means of light guidance, in which light's orbital angular momentum creates a centrifugal barrier for itself, thereby enabling low-loss transmission of light in a conventionally forb...
• Scientists plan a comeback for Ukraine's war-ravaged forests Destruction could open the door to management reforms AI翻译
  作者：Reese, April
• The evolution of two transmissible cancers in Tasmanian devils AI翻译
  作者：Stammnitz, Maximilian R.; Gori, Kevin; Kwon, Young Mi; Harry, Edward; Martin, Fergal J.; Billis, Konstantinos; Cheng, Yuanyuan; Baez-Ortega, Adrian; Chow, William; Comte, Sebastien; Eggertsson, Hannes; Fox, Samantha; Hamede, Rodrigo; Jones, Menna; Lazenby, Billie; Peck, Sarah; Pye, Ruth; Quail, Michael A.; Swift, Kate; Wang, Jinhong; Wood, Jonathan; Howe, Kerstin; Stratton, Michael R.; Ning, Zemin; Murchison, Elizabeth P.
  作者单位：University of Cambridge; Wellcome Trust Sanger Institute; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; University of Sydney; University of Tasmania; Department of Primary Industries & Regional Development NSW; Decode Genetics; Universite de Montpellier; University of Tasmania; Menzies Institute for Medical Research; Barcelona Institute of Science & Technology; Pompeu Fabra University; Centre de Regulacio Genomica (CRG)
  摘要：Tasmanian devils have spawned two transmissible cancer lineages, named devil facial tumor 1 (DFT1) and devil facial tumor 2 (DFT2). We investigated the genetic diversity and evolution of these clones by analyzing 78 DFT1 and 41 DFT2 genomes relative to a newly assembled, chromosome-level reference. Time-resolved phylogenetic trees reveal that DFT1 first emerged in 1986 (1982 to 1989) and DFT2 in 2011(2009 to 2012). Subclone analysis documents transmission of heterogeneous cell populations. DFT...
• Neurons that connect without synapses AI翻译
  作者：Dunn, Casey
  作者单位：Yale University
• Black doctors are Rx for longevity AI翻译
  作者：Brainard, Jeffrey
• Judicial interference with mifepristone AI翻译
  作者：Hamburg, Margaret; Sharfstein, Joshua
  作者单位：Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health
• Gun gatekeepers and their philosophies Individualism, conspiracism, and partisanship fuel American gun culture, argues a sociologist AI翻译
  作者：Lacombe, Matthew
  作者单位：University System of Ohio; Case Western Reserve University
• Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription AI翻译
  作者：Wilkinson, Max E.; Frangieh, Chris J.; Macrae, Rhiannon K.; Zhang, Feng
  作者单位：Howard Hughes Medical Institute; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
  摘要：Non-long terminal repeat (non-LTR) retrotransposons, or long interspersed nuclear elements (LINEs), are an abundant class of eukaryotic transposons that insert into genomes by target-primed reverse transcription (TPRT). During TPRT, a target DNA sequence is nicked and primes reverse transcription of the retrotransposon RNA. Here, we report the cryo-electron microscopy structure of the Bombyx mori R2 non-LTR retrotransposon initiating TPRT at its ribosomal DNA target. The target DNA sequence is...