作者：Balmford, Andrew; Brancalion, Pedro H. S.; Coomes, David; Filewod, Ben; Groom, Ben; Guizar-Coutino, Alejandro; Jones, Julia P. G.; Keshav, Srinivasan; Kontoleon, Andreas; Madhavapeddy, Anil; Malhi, Yadvinder; Sills, Erin O.; Strassburg, Bernardo B. N.; Venmans, Frank; West, Thales A. P.; Wheeler, Charlotte; Swinfield, Tom
作者单位：University of Cambridge; University of Cambridge; Universidade de Sao Paulo; University of Cambridge; University of Cambridge; University of London; London School Economics & Political Science; University of Exeter; Bangor University; University of Cambridge; University of Cambridge; University of Oxford; North Carolina State University; Pontificia Universidade Catolica do Rio de Janeiro; Vrije Universiteit Amsterdam
作者：Vinuesa, Carola G.; Grenov, Amalie; Kassiotis, George
作者单位：Francis Crick Institute; Imperial College London
摘要：Although all multicellular organisms have germ line-encoded innate receptors to sense pathogen -associated molecular patterns, vertebrates also evolved adaptive immunity based on somatically generated antigen receptors on B and T cells. Because randomly generated antigen receptors may also react with self-antigens, tolerance checkpoints operate to limit but not completely prevent autoimmunity. These two systems are intricately linked, with innate immunity playing an instrumental role in the in...
作者：Couzin, Iain D.; Couzin-Fuchs, Einat
作者单位：Max Planck Society; University of Konstanz; University of Konstanz
