作者:Klapper, Martin; Huebner, Alexander; Ibrahim, Anan; Wasmuth, Ina; Borry, Maxime; Haensch, Veit G.; Zhang, Shuaibing; Al-Jammal, Walid K.; Suma, Harikumar; Yates, James A. Fellows; Frangenberg, Jasmin; Velsko, Irina M.; Chowdhury, Somak; Herbst, Rosa; Bratovanov, Evgeni, V; Dahse, Hans-Martin; Horch, Therese; Hertweck, Christian; Morales, Manuel Ramon Gonzalez; Straus, Lawrence Guy; Vilotijevic, Ivan; Warinner, Christina; Stallforth, Pierre
作者单位:Leibniz Association; Hans Knoll Institute (HKI); Max Planck Society; Leibniz Association; Hans Knoll Institute (HKI); Leibniz Association; Hans Knoll Institute (HKI); Friedrich Schiller University of Jena; Leibniz Association; Hans Knoll Institute (HKI); Friedrich Schiller University of Jena; Universidad de Cantabria; Instituto Internacional de Investigaciones Prehistoricas de Cantabria (IIIPC); University of New Mexico; Universidad de Cantabria; Harvard University
摘要:Major advances over the past decade in the field of ancient DNA are providing access to past paleogenomic diversity, but the diverse functions and biosynthetic capabilities of this growing paleome remain largely elusive. We investigated the dental calculus of 12 Neanderthals and 52 anatomically modern humans ranging from 100,000 years ago to the present and reconstructed 459 bacterial metagenome-assembled genomes. We identified a biosynthetic gene cluster shared by seven Middle and Upper Paleo...