作者：Christ, Andrew J.; Rittenour, Tammy M.; Bierman, Paul R.; Keisling, Benjamin A.; Knutz, Paul C.; Thomsen, Tonny B.; Keulen, Nynke; Fosdick, Julie C.; Hemming, Sidney R.; Tison, Jean-Louis; Blard, Pierre-Henri; Steffensen, Jrgen P.; Caffee, Marc W.; Corbett, Lee B.; Dahl-Jensen, Dorthe; Dethier, David P.; Hidy, Alan J.; Perdrial, Nicolas; Peteet, Dorothy M.; Steig, Eric J.; Thomas, Elizabeth K.
作者单位：University of Vermont; University of Vermont; Utah System of Higher Education; Utah State University; University of Texas System; University of Texas Austin; Geological Survey Of Denmark & Greenland; University of Connecticut; Columbia University; Universite Libre de Bruxelles; Centre National de la Recherche Scientifique (CNRS); Universite de Lorraine; University of Copenhagen; Niels Bohr Institute; Purdue University System; Purdue University; Purdue University System; Purdue University; University of Manitoba; Williams College; United States Department of Energy (DOE); Lawrence Livermore National Laboratory; University of Vermont; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Goddard Institute for Space Studies; University of Washington; University of Washington Seattle; State University of New York (SUNY) System; University at Buffalo, SUNY
摘要：Past interglacial climates with smaller ice sheets offer analogs for ice sheet response to future warming and contributions to sea level rise; however, well-dated geologic records from formerly ice-free areas are rare. Here we report that subglacial sediment from the Camp Century ice core preserves direct evidence that northwestern Greenland was ice free during the Marine Isotope Stage (MIS) 11 interglacial. Luminescence dating shows that sediment just beneath the ice sheet was deposited by fl...
作者：Wu, Hao; Munoz, Elise N.; Hsieh, Laura J.; Chio, Un Seng; Gourdet, Muryam A.; Narlikar, Geeta J.; Cheng, Yifan
作者单位：University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; Howard Hughes Medical Institute
摘要：Unlike other chromatin remodelers, INO80 preferentially mobilizes hexasomes, which can form during transcription. Why INO80 prefers hexasomes over nucleosomes remains unclear. Here, we report structures of Saccharomyces cerevisiae INO80 bound to a hexasome or a nucleosome. INO80 binds the two substrates in substantially different orientations. On a hexasome, INO80 places its ATPase subunit, Ino80, at superhelical location -2 (SHL -2), in contrast to SHL -6 and SHL -7, as previously seen on nuc...
作者：Yu, Boyang; Duan, Jiangjiang
作者单位：Huazhong University of Science & Technology
作者：Cho, Adrian; Cassidy, David C.
作者单位：Hofstra University
