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作者：Stokstad, Erik
摘要：Botanists say transferring specimens to distant site is unnecessary and will hamper research
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作者：Tian, Wei; Zhou, Jingtian; Bartlett, Anna; Zeng, Qiurui; Liu, Hanqing; Castanon, Rosa G.; Kenworthy, Mia; Altshul, Jordan; Valadon, Cynthia; Aldridge, Andrew; Nery, Joseph R.; Chen, Huaming; Xu, Jiaying; Johnson, Nicholas D.; Lucero, Jacinta; Osteen, Julia K.; Emerson, Nora; Rink, Jon; Lee, Jasper; Li, Yang E.; Siletti, Kimberly; Liem, Michelle; Claffey, Naomi; O'Connor, Carolyn; Yanny, Anna Marie; Nyhus, Julie; Dee, Nick; Casper, Tamara; Shapovalova, Nadiya; Hirschstein, Daniel; Ding, Song-Lin; Hodge, Rebecca; Levi, Boaz P.; Keene, C. Dirk; Linnarsson, Sten; Lein, Ed; Ren, Bing; Behrens, M. Margarita; Ecker, Joseph R.
作者单位：Salk Institute; University of California System; University of California San Diego; University of California System; University of California San Diego; Salk Institute; Ludwig Institute for Cancer Research; Karolinska Institutet; Salk Institute; Allen Institute for Brain Science; University of Washington; University of Washington Seattle; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; Salk Institute; Howard Hughes Medical Institute
摘要：IINTRODUCTION The intricate gene-regulatory mechanisms governing the diverse cell types within the brain are paramount to comprehending its functions in both health and disease. The recent surge in high-throughput epigenomic profiling has heralded groundbreaking revelations into these gene-regulatory frameworks. Particularly, DNA methylation, in conjunction with the three-dimensional (3D) chromatin formations, underpins the fundamentals of gene regulation. This study comprehensively analyzed D...
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作者：Brainard, Jeffrey
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作者：Braun, Emelie; Danan-Gotthold, Miri; Borm, Lars E.; Lee, Ka Wai; Vinsland, Elin; Lonnerberg, Peter; Hu, Lijuan; Li, Xiaofei; He, Xiaoling; Andrusivova, Zaneta; Lundeberg, Joakim; Barker, Roger A.; Arenas, Ernest; Sundstrom, Erik; Linnarsson, Sten
作者单位：Karolinska Institutet; Karolinska Institutet; University of Cambridge; Royal Institute of Technology; Weizmann Institute of Science
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作者：Johansen, Nelson; Somasundaram, Saroja; Travaglini, Kyle J.; Yanny, Anna Marie; Shumyatcher, Maya; Casper, Tamara; Cobbs, Charles; Dee, Nick; Ellenbogen, Richard; Ferreira, Manuel; Goldy, Jeff; Guzman, Junitta; Gwinn, Ryder; Hirschstein, Daniel; Jorstad, Nikolas L.; Keene, C. Dirk; Ko, Andrew; Levi, Boaz P.; Ojemann, Jeffrey G.; Pham, Thanh; Shapovalova, Nadiya; Silbergeld, Daniel; Sulc, Josef; Torkelson, Amy; Tung, Herman; Smith, Kimberly; Lein, Ed S.; Bakken, Trygve E.; Hodge, Rebecca D.; Miller, Jeremy A.
作者单位：Allen Institute for Brain Science; Swedish Medical Center; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
摘要：INTRODUCTION Interindividual variation is a known feature of the human brain. In neocortical regions, broad classes of neurons and non-neuronal cells vary in abundance and gene expression in healthy adult humans, yet variation remains unexplored within finer divisions of cell types. Characterizing the effects of biological factors such as age, sex, ancestry, disease, or genetic variants on high-resolution cell types requires molecular profiling of single nuclei from large donor cohorts.RATIONA...
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作者：Rivas, Carlos A.; Navarro-Cerrillo, Rafael M.
作者单位：Universidad Tecnica de Manabi; Universidad de Cordoba
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作者：Thorp, H. Holden
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作者：Krammer, Florian; Ellebedy, Ali H.
作者单位：Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Washington University (WUSTL); Washington University (WUSTL)
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作者：Perez-Quezada, Jorge F.; Scherson, Rosa
作者单位：Universidad de Chile; Universidad de Chile
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作者：Maoz, Uri
作者单位：Chapman University System; Chapman University
摘要：A scientist presents a case for a predetermined future.
