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作者:Heckelmann, Ina; Bertrand, Mathieu; Dikopoltsev, Alexander; Beck, Mattias; Scalari, Giacomo; Faist, Jerome
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich
摘要:Synthetic lattices in photonics enable the exploration of light states in new dimensions, transcending phenomena common only to physical space. We propose and demonstrate a quantum walk comb in synthetic frequency space formed by externally modulating a ring-shaped semiconductor laser with ultrafast recovery times. The initially ballistic quantum walk does not dissipate into low supermode states of the synthetic lattice; instead, the state stabilizes in a broad frequency comb, unlocking the fu...
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作者:Wadman, Meredith
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作者:Sunami, Shinichi; Singh, Vijay Pal; Garrick, David; Beregi, Abel; Barker, Adam J.; Luksch, Kathrin; Bentine, Elliot; Mathey, Ludwig; Foot, Christopher J.
作者单位:University of Oxford; Leibniz University Hannover; Technology Innovation Institute; University of Hamburg; University of Hamburg; University of Hamburg
摘要:The understanding of nonequilibrium dynamics in many-body quantum systems is a fundamental issue in statistical physics. Experiments that probe universal properties of these systems can address such foundational questions. In this study, we report the measurement of universal dynamics triggered by a quench from the superfluid to normal phase across the Berezinskii-Kosterlitz-Thouless transition in a two-dimensional (2D) Bose gas. We reduced the density by splitting the 2D gas in two, realizing...
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作者:Cohen, Jon
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作者:Stuber, Garret D.
作者单位:University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
摘要:The nervous system coordinates various motivated behaviors such as feeding, drinking, and escape to promote survival and evolutionary fitness. Although the precise behavioral repertoires required for distinct motivated behaviors are diverse, common features such as approach or avoidance suggest that common brain substrates are required for a wide range of motivated behaviors. In this Review, I describe a framework by which neural circuits specified for some innate drives regulate the activity ...
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作者:Turek, Michal
作者单位:Polish Academy of Sciences; Institute of Biochemistry & Biophysics - Polish Academy of Sciences
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作者:Chabin, Michele
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作者:Saini, Eugenia
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作者:Lin, Lin; DeMartino, Jeff; Wang, Daisong; van Son, Gijs J. F.; van der Linden, Reinier; Begthel, Harry; Korving, Jeroen; Andersson-Rolf, Amanda; van den Brink, Stieneke; Lopez-Iglesias, Carmen; van de Wetering, Willine J.; Balwierz, Aleksandra; Margaritis, Thanasis; van de Wetering, Marc; Peters, Peter J.; Drost, Jarno; van Es, Johan H.; Clevers, Hans
作者单位:Royal Netherlands Academy of Arts & Sciences; Hubrecht Institute (KNAW); Princess Maxima Center; Maastricht University
摘要:Enteroendocrine cells (EECs) are hormone-producing cells residing in the epithelium of stomach, small intestine (SI), and colon. EECs regulate aspects of metabolic activity, including insulin levels, satiety, gastrointestinal secretion, and motility. The generation of different EEC lineages is not completely understood. In this work, we report a CRISPR knockout screen of the entire repertoire of transcription factors (TFs) in adult human SI organoids to identify dominant TFs controlling EEC di...
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作者:Boon, Sarah