6706期

最新文章

• Dutch academy rebukes duo AI翻译
  作者：Brainard, Jeffrey
• Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program AI翻译
  作者：Verma, Anurag; Huffman, Jennifer E.; Rodriguez, Alex; Conery, Mitchell; Liu, Molei; Ho, Yuk-Lam; Kim, Youngdae; Heise, David A.; Guare, Lindsay; Panickan, Vidul Ayakulangara; Garcon, Helene; Linares, Franciel; Costa, Lauren; Goethert, Ian; Tipton, Ryan; Honerlaw, Jacqueline; Davies, Laura; Whitbourne, Stacey; Cohen, Jeremy; Posner, Daniel C.; Sangar, Rahul; Murray, Michael; Wang, Xuan; Dochtermann, Daniel R.; Devineni, Poornima; Shi, Yunling; Nandi, Tarak Nath; Assimes, Themistocles L.; Brunette, Charles A.; Carroll, Robert J.; Clifford, Royce; Duvall, Scott; Gelernter, Joel; Hung, Adriana; Iyengar, Sudha K.; Joseph, Jacob; Kember, Rachel; Kranzler, Henry; Kripke, Colleen M.; Levey, Daniel; Luoh, Shiuh-Wen; Merritt, Victoria C.; Overstreet, Cassie; Deak, Joseph D.; Grant, Struan F. A.; Polimanti, Renato; Roussos, Panos; Shakt, Gabrielle; Sun, Yan V.; Tsao, Noah; Venkatesh, Sanan; Voloudakis, Georgios; Justice, Amy; Begoli, Edmon; Ramoni, Rachel; Tourassi, Georgia; Pyarajan, Saiju; Tsao, Philip; O'Donnell, Christopher J.; Muralidhar, Sumitra; Moser, Jennifer; Casas, Juan P.; Bick, Alexander G.; Zhou, Wei; Cai, Tianxi; Voight, Benjamin F.; Cho, Kelly; Gaziano, J. Michael; Madduri, Ravi K.; Damrauer, Scott; Liao, Katherine P.
  作者单位：University of Pennsylvania; University of Pennsylvania; Harvard University; Harvard University Medical Affiliates; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Boston Healthcare System; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Palo Alto Health Care System; Harvard University; Harvard Medical School; United States Department of Energy (DOE); Argonne National Laboratory; University of Pennsylvania; Columbia University; United States Department of Energy (DOE); Argonne National Laboratory; United States Department of Energy (DOE); Oak Ridge National Laboratory; Harvard University; Harvard Medical School; United States Department of Energy (DOE); Oak Ridge National Laboratory; Harvard University; Harvard University Medical Affiliates; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Boston Healthcare System; United States Department of Energy (DOE); Oak Ridge National Laboratory; United States Department of Energy (DOE); Oak Ridge National Laboratory; United States Department of Energy (DOE); Oak Ridge National Laboratory; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Utah System of Higher Education; University of Utah; Harvard University; Harvard University Medical Affiliates; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Boston Healthcare System; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Palo Alto Health Care System; Harvard University; Harvard University Medical Affiliates; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Boston Healthcare System; Vanderbilt University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA San Diego Healthcare System; University of California System; University of California San Diego; US Department of Veterans Affairs; Utah System of Higher Education; University of Utah; Yale University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Connecticut Healthcare System; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Tennessee Valley Healthcare System; Vanderbilt University; University System of Ohio; Case Western Reserve University; University System of Ohio; Case Western Reserve University; University System of Ohio; Case Western Reserve University; University System of Ohio; Case Western Reserve University; Brown University; University of Pennsylvania; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Connecticut Healthcare System; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Portland Health Care System; Oregon Health & Science University; Yale University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Connecticut Healthcare System; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; University of Pennsylvania; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; University of Pennsylvania; US Department of Veterans Affairs; Veterans Health Administration (VHA); James J. Peters VA Medical Center; Icahn School of Medicine at Mount Sinai; University of Pennsylvania; Emory University; Rollins School Public Health; Yale University; Yale University; United States Department of Energy (DOE); Oak Ridge National Laboratory; United States Department of Energy (DOE); Oak Ridge National Laboratory; Stanford University; Harvard University; Harvard University Medical Affiliates; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Boston Healthcare System; Vanderbilt University; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of Pennsylvania; University of Pennsylvania; Harvard University; Harvard University Medical Affiliates; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Boston Healthcare System; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital
  摘要：One of the justifiable criticisms of human genetic studies is the underrepresentation of participants from diverse populations. Lack of inclusion must be addressed at-scale to identify causal disease factors and understand the genetic causes of health disparities. We present genome-wide associations for 2068 traits from 635,969 participants in the Department of Veterans Affairs Million Veteran Program, a longitudinal study of diverse United States Veterans. Systematic analysis revealed 13,672 ...
• From forever chemicals to fluorine-free alternatives AI翻译
  作者：Ateia, Mohamed; Scheringer, Martin
  作者单位：United States Environmental Protection Agency; Rice University; Swiss Federal Institutes of Technology Domain; ETH Zurich; Masaryk University
  摘要：Per- and polyfluoroalkyl substances (PFAS) are a large group of more than 10,000 synthetic chemicals widely used for providing heat, water, oil, and stain resistance in applications such as nonstick coatings, firefighting foam, and food packaging. These forever chemicals are hazardous for human health and the environment, motivating efforts to find suitable replacements ( 1 ). The concerns surrounding PFAS are particularly serious because of their unusual persistence and widespread use, result...
• An even earlier last common ancestor AI翻译
  作者：Brainard, Jeffrey
• Birds optimize fruit size consumed near their geographic range limits AI翻译
  作者：Martins, Lucas P.; Stouffer, Daniel B.; Blendinger, Pedro G.; Boehning-Gaese, Katrin; Costa, Jose Miguel; Dehling, D. Matthias; Donatti, Camila I.; Emer, Carine; Galetti, Mauro; Heleno, Ruben; Menezes, Icaro; Morante-Filho, Jose Carlos; Munoz, Marcia C.; Neuschulz, Eike Lena; Pizo, Marco Aurelio; Quitian, Marta; Ruggera, Roman A.; Saavedra, Francisco; Santillan, Vinicio; Schleuning, Matthias; da Silva, Luis Pascoal; da Silva, Fernanda Ribeiro; Tobias, Joseph A.; Traveset, Anna; Vollstaedt, Maximilian G. R.; Tylianakis, Jason M.
  作者单位：University of Canterbury; Universidad Nacional de Tucuman; Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); Universidad Nacional de Tucuman; Universidad Nacional de Tucuman; Miguel Lillo Foundation; Goethe University Frankfurt; Universidade de Coimbra; Monash University; Conservation International; Northern Arizona University; Jardim Botanico do Rio de Janeiro; Universidade Estadual Paulista; State University System of Florida; Florida International University; Universidade Estadual de Santa Cruz; Universidad de La Salle; Consejo Superior de Investigaciones Cientificas (CSIC); ATTITUS Educacao; Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); Universidad Mayor de San Andres; Universidad Catolica de Cuenca; Universidade do Porto; Universidade do Porto; Imperial College London; University of Copenhagen; University of Canterbury
  摘要：Animals can adjust their diet to maximize energy or nutritional intake. For example, birds often target fruits that match their beak size because those fruits can be consumed more efficiently. We hypothesized that pressure to optimize diet-measured as matching between fruit and beak size-increases under stressful environments, such as those that determine species' range edges. Using fruit-consumption and trait information for 97 frugivorous bird and 831 plant species across six continents, we ...
• Probe to study close-by asteroid AI翻译
  作者：Brainard, Jeffrey
• Dynamics of high-speed electrical tree growth in electron-irradiated polymethyl methacrylate AI翻译
  作者：Sturge, Kathryn M.; Hoppis, Noah; Bussio, Ariana M.; Barney, Jonathan; Beaudoin, Brian; Brown, Cameron; Carlsten, Bruce; Chun, Carolyn; Clifford, Bryson C.; Cumings, John; Dallmann, Nicholas; Fitzgibbon, Jack; Frashure, Emily H.; Hammell, Ashley E.; Hannan, Jose; Henderson, Samuel L.; Hiebert, Miriam E.; Krutzler, James; Lichthardt, Joseph; Marr-Lyon, Mark; Montano, Thomas; Moody, Nathan; Mueller, Alexander; O'Shea, Patrick; Schneider, Ryan; Smith, Karl; Tappan, Bryce; Tiemann, Clayton; Walter, David; Koeth, Timothy W.
  作者单位：University System of Maryland; University of Maryland College Park; United States Department of Energy (DOE); Los Alamos National Laboratory
  摘要：Dielectric materials are foundational to our modern-day communications, defense, and commerce needs. Although dielectric breakdown is a primary cause of failure of these systems, we do not fully understand this process. We analyzed the dielectric breakdown channel propagation dynamics of two distinct types of electrical trees. One type of these electrical trees has not been formally classified. We observed the propagation speed of this electrical tree type to exceed 10 million meters per secon...
• Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells AI翻译
  作者：Lin, Zhi; Schaefer, Kaitlin; Lui, Irene; Yao, Zi; Fossati, Andrea; Swaney, Danielle L.; Palar, Ajikarunia; Sali, Andrej; Wells, James A.
  作者单位：University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; The J David Gladstone Institutes; University of California System; University of California San Francisco
  摘要：Proximity labeling proteomics (PLP) strategies are powerful approaches to yield snapshots of protein neighborhoods. Here, we describe a multiscale PLP method with adjustable resolution that uses a commercially available photocatalyst, Eosin Y, which upon visible light illumination activates different photo-probes with a range of labeling radii. We applied this platform to profile neighborhoods of the oncogenic epidermal growth factor receptor and orthogonally validated more than 20 neighbors u...
• Cruise set to restore critical Indian Ocean mooring array AI翻译
  作者：Chandrashekar, Vaishnavi
• High bar for famine declaration delays food aid AI翻译
  作者：Roberts, Leslie
  摘要：Lack of humanitarian action during early stages of acute food insecurity takes a heavy toll