6710期

最新文章

• 23andMe ends drug discovery AI翻译
  作者：Brainard, Jeffrey
• Frustration boils over at storied physics lab AI翻译
  作者：Cho, Adrian
  摘要：Planned staff furlough at Fermilab highlights continuing management troubles
• Hoof Beats: How Horses Shaped Human History AI翻译
  作者：Larson, Greger
  作者单位：University of Oxford
• A hippocampal circuit mechanism to balance memory reactivation during sleep AI翻译
  作者：Karaba, Lindsay A.; Robinson, Heath L.; Harvey, Ryan E.; Chen, Weiwei; Fernandez-Ruiz, Antonio; Oliva, Azahara
  作者单位：Cornell University
  摘要：Memory consolidation involves the synchronous reactivation of hippocampal cells active during recent experience in sleep sharp-wave ripples (SWRs). How this increase in firing rates and synchrony after learning is counterbalanced to preserve network stability is not understood. We discovered a network event generated by an intrahippocampal circuit formed by a subset of CA2 pyramidal cells to cholecystokinin-expressing (CCK+) basket cells, which fire a barrage of action potentials (BARR) during...
• A solid noncovalent organic double-helix framework catalyzes asymmetric [6+4] cycloaddition AI翻译
  作者：Zheng, Tianyu; Noethling, Nils; Wang, Zikuan; Mitschke, Benjamin; Leutzsch, Markus; List, Benjamin
  作者单位：Max Planck Society
  摘要：Whereas [4 + 2] cycloadditions are among the most powerful tools in the chemist's synthetic arsenal, controlling reactivity and selectivity of [6 + 4] cycloadditions has proven to be extremely challenging. Such transformations, especially if compatible with simple hydrocarbon-based substrates, could ultimately provide a general approach to highly valuable and otherwise difficult to access 10-membered rings. We report here that highly acidic and confined imidodiphosphorimidate catalysts do not ...
• 撤稿声明: A room-temperature single-photon source based on strongly interacting Rydberg atoms AI翻译
  作者：Ripka, Fabian; Kuebler, Harald; Loew, Robert; Pfau, Tilman
  作者单位：University of Stuttgart
• Troubled waters AI翻译
  作者：Attride, Dawn
  摘要：In an iconic corner of the Grand Canyon, a uranium mine may threaten a tribe's sole water source
• US blocks herbicide over health AI翻译
  作者：Brainard, Jeffrey
• Visualizing synaptic pruning in the mammalian brain AI翻译
  作者：Somaiya, Rachana Deven; Feller, Marla B.
  作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley
  摘要：Patterns of spontaneous neuronal activity instruct the refinement of developing brain circuits
• What's next for psychedelics after MDMA rejection? AI翻译
  作者：Kupferschmidt, Kai
  摘要：Lykos's failure to win FDA approval for PTSD therapy may accelerate a strategic shift among its competitors