作者:Chekroud, Adam M.; Hawrilenko, Matt; Loho, Hieronimus; Bondar, Julia; Gueorguieva, Ralitza; Hasan, Alkomiet; Kambeitz, Joseph; Corlett, Philip R.; Koutsouleris, Nikolaos; Krumholz, Harlan M.; Krystal, John H.; Paulus, Martin
作者单位:Yale University; Yale University; University of Augsburg; University of Cologne; University of Cologne; University of Munich; Yale University; Laureate Institute for Brain Research, Inc.
摘要:It is widely hoped that statistical models can improve decision-making related to medical treatments. Because of the cost and scarcity of medical outcomes data, this hope is typically based on investigators observing a model's success in one or two datasets or clinical contexts. We scrutinized this optimism by examining how well a machine learning model performed across several independent clinical trials of antipsychotic medication for schizophrenia. Models predicted patient outcomes with hig...
作者:Wetzer, Thom; Stuart-Smith, Rupert; Dibley, Arjuna
作者单位:University of Oxford; University of Oxford; University of Melbourne; University of Melbourne
作者:Petzschner, Frederike H.
作者单位:Brown University
作者:Hemraj, Deevesh A.; Bishop, Melanie; Carstensen, Jacob; Krause-Jensen, Dorte; Staehr, Peter A. U.; Russell, Bayden D.
作者单位:Aarhus University; Macquarie University; Aarhus University; University of Hong Kong; University of Hong Kong; University of Hong Kong
作者:Slesarenko, Viacheslav; Pastewka, Lars
作者单位:University of Freiburg; University of Freiburg