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作者：Viard, Mathias; O'hUigin, Colm; Yuki, Yuko; Bashirova, Arman A.; Collins, David R.; Urbach, Jonathan M.; Wolinsky, Steven; Buchbinder, Susan; Kirk, Gregory D.; Goedert, James J.; Michael, Nelson L.; Haas, David W.; Deeks, Steven G.; Walker, Bruce D.; Yu, Xu; Carrington, Mary
作者单位：National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); Frederick National Laboratory for Cancer Research; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); Harvard University; Massachusetts Institute of Technology (MIT); Ragon Institute; Harvard University; Northwestern University; Feinberg School of Medicine; San Francisco Department of Public Health; University of California System; University of California San Francisco; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); NIH National Cancer Institute- Division of Cancer Epidemiology & Genetics; Walter Reed Army Institute of Research (WRAIR); United States Department of Defense; United States Army; Vanderbilt University; University of California System; University of California San Francisco; Howard Hughes Medical Institute
摘要：Heterozygosity of Human leukocyte antigen (HLA) class I genes is linked to beneficial outcomes after HIV infection, presumably through greater breadth of HIV epitope presentation and cytotoxic T cell response. Distinct allotype pairs, however, differ in the extent to which they bind shared sets of peptides. We developed a functional divergence metric that measures pairwise complementarity of allotype-associated peptide binding profiles. Greater functional divergence for pairs of HLA-A and/or H...
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作者：Cervia-Hasler, Carlo; Brueningk, Sarah C.; Hoch, Tobias; Fan, Bowen; Muzio, Giulia; Thompson, Ryan C.; Ceglarek, Laura; Meledin, Roman; Westermann, Patrick; Emmenegger, Marc; Taeschler, Patrick; Zurbuchen, Yves; Pons, Michele; Menges, Dominik; Ballouz, Tala; Cervia-Hasler, Sara; Adamo, Sarah; Merad, Miriam; Charney, Alexander W.; Puhan, Milo; Brodin, Petter; Nilsson, Jakob; Aguzzi, Adriano; Raeber, Miro E.; Messner, Christoph B.; Beckmann, Noam D.; Borgwardt, Karsten; Boyman, Onur
作者单位：University of Zurich; University Zurich Hospital; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Institute of Bioinformatics; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; University of Zurich; Swiss Institute of Allergy & Asthma Research; University of Zurich; University Zurich Hospital; University of Zurich; Swiss School of Public Health (SSPH+); Karolinska Institutet; Imperial College London; Icahn School of Medicine at Mount Sinai; University of Zurich; University of Geneva; University of Zurich
摘要：Long Covid is a debilitating condition of unknown etiology. We performed multimodal proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after confirmed severe acute respiratory syndrome coronavirus 2 infection. Analysis of >6500 proteins in 268 longitudinal samples revealed dysregulated activation of the complement system, an innate immune protection and homeostasis mechanism, in individuals experiencing Long Covid. Thus, active Long Covid was characterized by te...
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作者：Brainard, Jeffrey
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作者：Meijaard, Erik; Erman, Andi; Ancrenaz, Marc; Goossens, Benoit
作者单位：Cardiff University
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作者：Turner, Alexis
作者单位：Harvard University
摘要：A pair of anthropologists' personal papers shed light on US psychedelic science in the mid-20th century
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作者：Ruf, Wolfram
作者单位：Johannes Gutenberg University of Mainz; Scripps Research Institute
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作者：Service, Robert F.
摘要：Efficient method for creating proteins with unusual amino acids opens the door to new medicines and catalysts
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作者：Pironon, S.; Ondo, I.; Diazgranados, M.; Allkin, R.; Baquero, A. C.; Camara-Leret, R.; Canteiro, C.; Dennehy-Carr, Z.; Govaerts, R.; Hargreaves, S.; Hudson, A. J.; Lemmens, R.; Milliken, W.; Nesbitt, M.; Patmore, K.; Schmelzer, G.; Turner, R. M.; van Andel, T. R.; Ulian, T.; Antonelli, A.; Willis, K. J.
作者单位：Royal Botanic Gardens, Kew; New York Botanical Garden; University of Zurich; University of Reading; Royal Botanic Gardens, Kew; Royal Botanic Gardens, Kew; Wageningen University & Research; University of London; Royal Holloway University London; University of London; University College London; Naturalis Biodiversity Center; University of Turin; University of Gothenburg; University of Oxford; University of London; Queen Mary University London
摘要：Plants sustain human life. Understanding geographic patterns of the diversity of species used by people is thus essential for the sustainable management of plant resources. Here, we investigate the global distribution of 35,687 utilized plant species spanning 10 use categories (e.g., food, medicine, material). Our findings indicate general concordance between utilized and total plant diversity, supporting the potential for simultaneously conserving species diversity and its contributions to pe...
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作者：Konno, Shunya; Asavanant, Warit; Hanamura, Fumiya; Nagayoshi, Hironari; Fukui, Kosuke; Sakaguchi, Atsushi; Ide, Ryuhoh; China, Fumihiro; Yabuno, Masahiro; Miki, Shigehito; Terai, Hirotaka; Takase, Kan; Endo, Mamoru; Marek, Petr; Filip, Radim; van Loock, Peter; Furusawa, Akira
作者单位：University of Tokyo; RIKEN; National Institute of Information & Communications Technology (NICT) - Japan; Kobe University; Palacky University Olomouc; Johannes Gutenberg University of Mainz; NTT, Inc
摘要：To harness the potential of a quantum computer, quantum information must be protected against error by encoding it into a logical state that is suitable for quantum error correction. The Gottesman-Kitaev-Preskill (GKP) qubit is a promising candidate because the required multiqubit operations are readily available at optical frequency. To date, however, GKP qubits have been demonstrated only at mechanical and microwave frequencies. We realized a GKP state in propagating light at telecommunicati...
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作者：Voosen, Paul
